All Outputs (3)

The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria (2016)
Journal Article
Rauch, C., Cherkaoui-Rbati, M., Egan, S. A., & Leigh, J. A. (2017). The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria. BBA - Biomembranes, 1859(2), https://doi.org/10.1016/j.bbamem.2016.12.002

Background: The anionic-polyelectrolyte nature of the wall of Gram-positive bacteria has long been suspected to be involved in homeostasis of essential cations and bacterial growth. A better understanding of the coupling between the biophysics and th... Read More about The bio-physics of condensation of divalent cations into the bacterial wall has implications for growth of Gram-positive bacteria.

PIMMS (Pragmatic Insertional Mutation Mapping System) laboratory methodology a readily accessible tool for identification of essential genes in Streptococcus (2016)
Journal Article
Blanchard, A. M., Egan, S. A., Emes, R. D., Warry, A., & Leigh, J. A. (2016). PIMMS (Pragmatic Insertional Mutation Mapping System) laboratory methodology a readily accessible tool for identification of essential genes in Streptococcus. Frontiers in Microbiology, 7(1645), https://doi.org/10.3389/fmicb.2016.01645

The Pragmatic Insertional Mutation Mapping (PIMMS) laboratory protocol was developed alongside various bioinformatics packages (Blanchard et al., 2015) to enable detection of essential and conditionally essential genes in Streptococcus and related ba... Read More about PIMMS (Pragmatic Insertional Mutation Mapping System) laboratory methodology a readily accessible tool for identification of essential genes in Streptococcus.

Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages (2016)
Journal Article
Günther, J., Czabanska, A., Bauer, I., Leigh, J. A., Holst, O., & Seyfert, H. (2016). Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages. Veterinary Research, 47(13), https://doi.org/10.1186/s13567-015-0287-8

Streptococcus uberis is frequently isolated from the mammary gland of dairy cattle. Infection with some strains can induce mild subclinical inflammation whilst others induce severe inflammation and clinical mastitis. We compared here the inflammatory... Read More about Streptococcus uberis strains isolated from the bovine mammary gland evade immune recognition by mammary epithelial cells, but not of macrophages.