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All Outputs (3)

Damage limitation (2016)
Journal Article
Amelio, I., & Melino, G. (2016). Damage limitation. eLife, 5, https://doi.org/10.7554/elife.17394

A spring-loaded mechanism can explain the activation process for a protein that has a crucial role in maintaining the genomic integrity of immature eggs cells.

Vascular ageing and endothelial cell senescence: Molecular mechanisms of physiology and diseases (2016)
Journal Article
Regina, C., Panatta, E., Candi, E., Melino, G., Amelio, I., Balistreri, C. R., …Ruvolo, G. (2016). Vascular ageing and endothelial cell senescence: Molecular mechanisms of physiology and diseases. Mechanisms of Ageing and Development, 159, 14-21. https://doi.org/10.1016/j.mad.2016.05.003

Ageing leads to a progressive deterioration of structure and function of all organs over the time. During this process endothelial cells undergo senescence and manifest significant changes in their properties, resulting in impairment of the vascular... Read More about Vascular ageing and endothelial cell senescence: Molecular mechanisms of physiology and diseases.