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Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction (2016)
Journal Article
Tubby, C., Negm, O. H., Harrison, T. W., Tighe, P. J., Todd, I., & Fairclough, L. C. (2017). Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction. Journal of Asthma, 54(5), 456-466. https://doi.org/10.1080/02770903.2016.1236941

Objective: The three main types of killer cells – CD8+ T cells, NK cells and NKT cells – have been linked to asthma and chronic obstructive pulmonary disease (COPD). However, their role in a small subset of asthma patients displaying fixed airway obs... Read More about Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction.

The application of protein microarray assays in psychoneuroimmunology (2016)
Journal Article
Ayling, K., Bowden, T., Tighe, P., Todd, I., Dilnot, E. M., Negm, O., …Vedhara, K. (2017). The application of protein microarray assays in psychoneuroimmunology. Brain, Behavior, and Immunity, 59, 62-66. https://doi.org/10.1016/j.bbi.2016.09.013

Protein microarrays are miniaturized multiplex assays that exhibit many advantages over the commonly used enzyme-linked immunosorbent assay (ELISA). This article aims to introduce protein microarrays to readers of Brain, Behavior, and Immunity and de... Read More about The application of protein microarray assays in psychoneuroimmunology.

Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease (2016)
Journal Article
Selvarajah, S., Todd, I., Tighe, P. J., John, M., Bolton, C. E., Harrison, T. W., & Fairclough, L. C. (2016). Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease. Mediators of Inflammation, 2016, 1-9. https://doi.org/10.1155/2016/3604842

Inflammatory biomarkers, including cytokines, are associated with COPD, but the association of particular circulating cytokines with systemic pathology remains equivocal. To investigate this, we developed a protein microarray system to detect multipl... Read More about Multiple Circulating Cytokines Are Coelevated in Chronic Obstructive Pulmonary Disease.