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All Outputs (9)

In Vivo Assessment of Brainstem Depigmentation in Parkinson Disease: Potential as a Severity Marker for Multicenter Studies (2016)
Journal Article
Schwarz, S. T., Xing, Y., Tomar, P., Bajaj, N., & Auer, D. P. (2017). In Vivo Assessment of Brainstem Depigmentation in Parkinson Disease: Potential as a Severity Marker for Multicenter Studies. Radiology, 283(3), 789-798. https://doi.org/10.1148/radiol.2016160662

Purpose: To investigate the pattern of neuromelanin signal intensity loss within the substantia nigra pars compacta (SNpc), locus coeruleus, and ventral tegmental area in Parkinson disease (PD); the specific aims were (a) to study regional magnetic... Read More about In Vivo Assessment of Brainstem Depigmentation in Parkinson Disease: Potential as a Severity Marker for Multicenter Studies.

Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging (2016)
Journal Article
Faas, H., Taylor, A. J., Granwehr, J., Lesbats, C., Krupa, J. L., Six, J. S., …Meersmann, T. (2016). Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging. PLoS ONE, 11(10), e0163704. https://doi.org/10.1371/journal.pone.0163704

© 2016 Taylor et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cre... Read More about Probe-Specific Procedure to Estimate Sensitivity and Detection Limits for 19F Magnetic Resonance Imaging.

Cerebral Cortical Thickness in Chronic Pain Due to Knee Osteoarthritis: The Effect of Pain Duration and Pain Sensitization (2016)
Journal Article
Alshuft, H., Condon, L., Dineen, R. A., & Auer, D. P. (in press). Cerebral Cortical Thickness in Chronic Pain Due to Knee Osteoarthritis: The Effect of Pain Duration and Pain Sensitization. PLoS ONE, 11(9), Article e0161687. https://doi.org/10.1371/journal.pone.0161687

Objective This study investigates associations between cortical thickness and pain duration, and central sensitization as markers of pain progression in painful knee osteoarthritis. Methods Whole brain cortical thickness and pressure pain th... Read More about Cerebral Cortical Thickness in Chronic Pain Due to Knee Osteoarthritis: The Effect of Pain Duration and Pain Sensitization.

Lesion topography and microscopic white matter tract damage contribute to cognitive impairment in symptomatic carotid artery disease (2016)
Journal Article
Meng, D., Hosseini, A. A., Simpson, R. J., Shaikh, Q., Tench, C. R., Dineen, R. A., & Auer, D. P. (2017). Lesion topography and microscopic white matter tract damage contribute to cognitive impairment in symptomatic carotid artery disease. Radiology, 282(2), 502-515. https://doi.org/10.1148/radiol.2016152685

Purpose: To investigate associations between neuroimaging markers of cerebrovascular disease, including lesion topography and extent and severity of strategic and global cerebral tissue injury, and cognition in carotid artery disease (CAD). Material... Read More about Lesion topography and microscopic white matter tract damage contribute to cognitive impairment in symptomatic carotid artery disease.

Novel Methods for Microglia Segmentation, Feature Extraction, and Classification (2016)
Journal Article
Ding, Y., Pardon, M. C., Agostini, A., Faas, H., Duan, J., Ward, W. O., …Bai, L. (2016). Novel Methods for Microglia Segmentation, Feature Extraction, and Classification. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 14(6), 1366-1377. https://doi.org/10.1109/TCBB.2016.2591520

© 2017 IEEE. Segmentation and analysis of histological images provides a valuable tool to gain insight into the biology and function of microglial cells in health and disease. Common image segmentation methods are not suitable for inhomogeneous histo... Read More about Novel Methods for Microglia Segmentation, Feature Extraction, and Classification.

Functional reorganisation in chronic pain and neural correlates of pain sensitisation (2016)
Journal Article
Tanasescu, R., Cottam, W., Condon, L., Tench, C. R., & Auer, D. P. (2016). Functional reorganisation in chronic pain and neural correlates of pain sensitisation. Neuroscience and Biobehavioral Reviews, 68, 120-133. https://doi.org/10.1016/j.neubiorev.2016.04.001

© 2016 Published by Elsevier Ltd. Maladaptive mechanisms of pain processing in chronic pain conditions (CP) are poorly understood. We used coordinate based meta-analysis of 266 fMRI pain studies to study functional brain reorganisation in CP and expe... Read More about Functional reorganisation in chronic pain and neural correlates of pain sensitisation.

Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain (2016)
Journal Article
Abaei, M., Sagar, D. R., Stockley, E. G., Spicer, C. H., Prior, M., Chapman, V., & Auer, D. P. (in press). Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain. Molecular Pain, 12, https://doi.org/10.1177/1744806916642445

Background: The mechanisms driving osteoarthritic pain remain poorly understood, but there is increasing evidence for a role of the central nervous system in the chronification of pain.We used functional magnetic resonance imaging to investigate the... Read More about Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain.