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Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines (2016)
Journal Article
Ivanov, D., Walker, D., Coyle, B., & Grabowska, A. (2016). Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines. Data in Brief, 9, 696-698. https://doi.org/10.1016/j.dib.2016.10.004

This article collates information about the number of scientific articles mentioning each of the established medulloblastoma cell lines, derived through a systematic search of Web of Science, Scopus and Google Scholar in 2016. The data for each cell... Read More about Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines.

In vitro models of medulloblastoma: choosing the right tool for the job (2016)
Journal Article
Ivanov, D. P., Coyle, B., Walker, D. A., & Grabowska, A. M. (2016). In vitro models of medulloblastoma: choosing the right tool for the job. Journal of Biotechnology, 236, 10-25. https://doi.org/10.1016/j.jbiotec.2016.07.028

The recently-defined four molecular subgroups of medulloblastoma have required updating of our understanding of in vitro models to include molecular classification and risk stratification features from clinical practice. This review seeks to build a... Read More about In vitro models of medulloblastoma: choosing the right tool for the job.

A genetic assay for gene essentiality in Clostridium (2016)
Journal Article
Walker, D. J., Heap, J. T., Winzer, K., & Minton, N. P. (2016). A genetic assay for gene essentiality in Clostridium. Anaerobe, 42, 40-43. https://doi.org/10.1016/j.anaerobe.2016.07.007

Essential genes of pathogens are potential therapeutic targets, but are difficult to verify. Here, gene essentiality was determined by targeted knockout following engineered gene duplication. Null mutants of candidate essential genes of Clostridium d... Read More about A genetic assay for gene essentiality in Clostridium.

Highlights of children with Cancer UK’s workshop on drug delivery in paediatric brain tumours (2016)
Journal Article
Nailor, A., Walker, D. A., Jacques, T. S., Warren, K. E., Brem, H., Kearns, P. R., …Kilday, J. (2016). Highlights of children with Cancer UK’s workshop on drug delivery in paediatric brain tumours. ecancermedicalscience, 10(630), https://doi.org/10.3332/ecancer.2016.630

The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leadi... Read More about Highlights of children with Cancer UK’s workshop on drug delivery in paediatric brain tumours.

Penetration and intracellular uptake of poly(glycerol-adipate)nanoparticles into 3-dimensional brain tumour cell culture models (2016)
Journal Article
Meng, W., Garnett, M. C., Walker, D. A., & Parker, T. L. (2016). Penetration and intracellular uptake of poly(glycerol-adipate)nanoparticles into 3-dimensional brain tumour cell culture models. Experimental Biology and Medicine, 241(5), https://doi.org/10.1177/1535370215610441

Nanoparticle (NP) drug delivery systems may potentially enhance the efficacy of therapeutic agents. It is difficult to characterise many important properties of NPs in vivo and therefore attempts have been made to use realistic in vitro multicellular... Read More about Penetration and intracellular uptake of poly(glycerol-adipate)nanoparticles into 3-dimensional brain tumour cell culture models.