Skip to main content

Research Repository

Advanced Search

All Outputs (10)

The environmental deposition of influenza virus from patients infected with influenza A(H1N1)pdm09: Implications for infection prevention and control (2015)
Journal Article
Killingley, B., Killingley, B., Greatorex, J., Digard, P., Wise, H., Garcia, F., …Nguyen-Van-Tam, J. S. (2016). The environmental deposition of influenza virus from patients infected with influenza A(H1N1)pdm09: Implications for infection prevention and control. Journal of Infection and Public Health, 9(3), 278-288. https://doi.org/10.1016/j.jiph.2015.10.009

In a multi-center, prospective, observational study over two influenza seasons, we sought to quantify and correlate the amount of virus recovered from the nares of infected subjects with that recovered from their immediate environment in community an... Read More about The environmental deposition of influenza virus from patients infected with influenza A(H1N1)pdm09: Implications for infection prevention and control.

Influenza vaccines really work? Keeping apart the true from the false (2015)
Journal Article
Nguyen-Van-Tam, J., Gross, D., Sturkenboom, M., & Parrish-Sprowl, J. (2015). Influenza vaccines really work? Keeping apart the true from the false. Vaccine, 33(49), https://doi.org/10.1016/j.vaccine.2015.08.052

A yearly seasonal flu vaccine is the best preventive method we have against influenza at this time. Even then, vaccination adoption is hampered by on-going discussions about safety and effectiveness. In order to dot the I's and cross the T's at the f... Read More about Influenza vaccines really work? Keeping apart the true from the false.

Evaluation of the ‘Live Life Better Service’, a community-based weight management service, for morbidly obese patients (2015)
Journal Article
Wallace, D., Myles, P., Holt, R., & Van-Tam, J. N. (2016). Evaluation of the ‘Live Life Better Service’, a community-based weight management service, for morbidly obese patients. Journal of Public Health, 38(2), e138-e149. https://doi.org/10.1093/pubmed/fdv103

Background There is a limited evidence on the effectiveness of lifestyle interventions in achieving and maintaining a significant level of weight loss in morbidly obese patients. This study evaluated the impact on weight loss and psychological wel... Read More about Evaluation of the ‘Live Life Better Service’, a community-based weight management service, for morbidly obese patients.

Natural T Cell–mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study (2015)
Journal Article
Hayward, A. C., Wang, L., Goonetilleke, N., Fragaszy, E. B., Bermingham, A., Copas, A., …McMichael, A. J. (2015). Natural T Cell–mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study. American Journal of Respiratory and Critical Care Medicine, 191(12), 1422-1431. https://doi.org/10.1164/rccm.201411-1988oc

Rationale: A high proportion of influenza infections are asymptomatic. Animal and human challenge studies and observational studies suggest T cells protect against disease among those infected, but the impact of T-cell immunity at the population leve... Read More about Natural T Cell–mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study.

Association between benzodiazepine use and exacerbations and mortality in patients with asthma: a matched case-control and survival analysis using the United Kingdom Clinical Practice Research Datalink (2015)
Journal Article
Nakafero, G., Sanders, R. D., Nguyen-Van-Tam, J. S., & Myles, P. R. (2015). Association between benzodiazepine use and exacerbations and mortality in patients with asthma: a matched case-control and survival analysis using the United Kingdom Clinical Practice Research Datalink. Pharmacoepidemiology and Drug Safety, 24(8), 793-802. https://doi.org/10.1002/pds.3799

Purpose: To investigate the association between the GABAergic drugs, benzodiazepines or zopiclone, and the occurrence of asthma exacerbations and subsequent mortality in a cohort of asthma patients. Methods: 105,747 patients without asthma exacerba... Read More about Association between benzodiazepine use and exacerbations and mortality in patients with asthma: a matched case-control and survival analysis using the United Kingdom Clinical Practice Research Datalink.

Healthcare workers' willingness to work during an influenza pandemic: a systematic review and meta-analysis (2015)
Journal Article
Aoyagi, Y., Beck, C. R., Dingwall, R., & Nguyen-Van-Tam, J. (2015). Healthcare workers' willingness to work during an influenza pandemic: a systematic review and meta-analysis. Influenza and Other Respiratory Viruses, 9(3), 120-130. https://doi.org/10.1111/irv.12310

To estimate the proportion of healthcare workers (HCWs) willing to work during an influenza pandemic and identify associated risk factors, we undertook a systematic review and meta-analysis compliant with PRISMA guidance. Databases and grey literatur... Read More about Healthcare workers' willingness to work during an influenza pandemic: a systematic review and meta-analysis.

Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation (2015)
Journal Article
Lim, W. S., Brittain, C., Duley, L., Edwards, S., Gordon, S., Montgomery, A., …Wootton, D. (2015). Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation. Health Technology Assessment, 19(16), https://doi.org/10.3310/hta19160

Background: There are no completed randomised trials of the use of corticosteroids in patients with severe influenza infection. Corticosteroid use in influenza is widespread, non-systematic and marked by controversy. A recent meta-analysis of observa... Read More about Blinded randomised controlled trial of low-dose Adjuvant Steroids in Adults admitted to hospital with Pandemic influenza (ASAP): a trial 'in hibernation', ready for rapid activation.

Impact of infection control interventions on rates of Staphylococcus aureus bacteraemia in National Health Service acute hospitals, East Midlands, UK, using interrupted time-series analysis (2015)
Journal Article
Newitt, S., Myles, P. R., Birkin, J., Maskell, V., Slack, R., Nguyen-Van-Tam, J., & Szatkowski, L. (in press). Impact of infection control interventions on rates of Staphylococcus aureus bacteraemia in National Health Service acute hospitals, East Midlands, UK, using interrupted time-series analysis. Journal of Hospital Infection, 90(1), https://doi.org/10.1016/j.jhin.2014.12.016

Background: Reducing healthcare-associated infection (HCAI) is a UK national priority. Multiple national and regional interventions aimed at reduction have been implemented in National Health Service acute hospitals, but assessment of their effective... Read More about Impact of infection control interventions on rates of Staphylococcus aureus bacteraemia in National Health Service acute hospitals, East Midlands, UK, using interrupted time-series analysis.