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The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress (2015)
Journal Article
Takahashi, H., Oshima, T., Hobman, J. L., Doherty, N., Clayton, S. R., Iqbal, M., …Stekel, D. J. (2015). The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress. Interface, 12(106), Article 20150069. https://doi.org/10.1098/rsif.2015.0069

Zinc is essential for life, but toxic in excess. Thus all cells must control their internal zinc concentration. We used a systems approach, alternating rounds of experiments and models, to further elucidate the zinc control systems in Escherichia col... Read More about The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress.

A machine learning heuristic to identify biologically relevant and minimal biomarker panels from omics data (2015)
Journal Article
Swan, A. L., Stekel, D. J., Hodgman, C., Allaway, D., Alqahtani, M. H., Mobasheri, A., & Bacardit, J. (2015). A machine learning heuristic to identify biologically relevant and minimal biomarker panels from omics data. BMC Genomics, 16(Suppl 1), doi:10.1186/1471-2164-16-s1-s2

Background: Investigations into novel biomarkers using omics techniques generate large amounts of data. Due to their size and numbers of attributes, these data are suitable for analysis with machine learning methods. A key component of typical machin... Read More about A machine learning heuristic to identify biologically relevant and minimal biomarker panels from omics data.