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The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization (2015)
Journal Article
Salazar, F., Hall, L., Negm, O. H., Awuah, D., Tighe, P. J., Shakib, F., & Ghaemmaghami, A. M. (2016). The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization. Journal of Allergy and Clinical Immunology, 137(6), 1841-1851.e2. https://doi.org/10.1016/j.jaci.2015.10.033

Background: Dendritic cells (DCs) are key players in the induction and re-elicitation of TH2 responses to allergens. We have previously shown that different C-type lectin receptors on DCs play a major role in allergen recognition and uptake. In parti... Read More about The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization.