All Outputs (3)

Plasmodium P-type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes (2015)
Journal Article
Roques, M., Wall, R. J., Douglass, A. P., Ramaprasad, A., Ferguson, D. J. P., Kaindama, M. L., …Tewari, R. (2015). Plasmodium P-type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes. PLoS Pathogens, 11(11), Article e1005273. https://doi.org/10.1371/journal.ppat.1005273

Cell-cycle progression and cell division in eukaryotes are governed in part by the cyclin family and their regulation of cyclin-dependent kinases (CDKs). Cyclins are very well characterised in model systems such as yeast and human cells, but surprisi... Read More about Plasmodium P-type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes.

Identification of the ISWI chromatin remodeling complex of the early branching Eukaryote Trypanosoma brucei (2015)
Journal Article
Stanne, T., Shankar Narayanan, M., Ridewood, S., Ling, A., Witmer, K., Kushwaha, M., …Rudenko, G. (2015). Identification of the ISWI chromatin remodeling complex of the early branching Eukaryote Trypanosoma brucei. Journal of Biological Chemistry, 290, https://doi.org/10.1074/jbc.M115.679019

ISWI chromatin remodelers are highly conserved in eukaryotes and are important for the assembly and spacing of nucleosomes, thereby controlling transcription initiation and elongation. ISWI is typically associated with different subunits, forming sp... Read More about Identification of the ISWI chromatin remodeling complex of the early branching Eukaryote Trypanosoma brucei.

Architecture of a host–parasite interface: complex targeting mechanisms revealed through proteomics (2015)
Journal Article
Gadelha, C., Zhang, W., Chamberlain, J. W., Chait, B. T., Wickstead, B., & Field, M. C. (2015). Architecture of a host–parasite interface: complex targeting mechanisms revealed through proteomics. Molecular and Cellular Proteomics, 14(7), https://doi.org/10.1074/mcp.M114.047647

Surface membrane organization and composition is key to cellular function, and membrane proteins serve many essential roles in endocytosis, secretion, and cell recognition. The surface of parasitic organisms, however, is a double-edged sword; this is... Read More about Architecture of a host–parasite interface: complex targeting mechanisms revealed through proteomics.