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Chicken and duck myotubes are highly susceptible and permissive to influenza virus infection (2014)
Journal Article
Baquero-Perez, B., Kuchipudi, S. V., Ho, J., Sebastian, S., Puranik, A., Howard, W., …Chang, K. (2015). Chicken and duck myotubes are highly susceptible and permissive to influenza virus infection. Journal of Virology, 89(5), https://doi.org/10.1128/JVI.03421-14

Skeletal muscle, at 30 to 40% of body mass, is the most abundant soft tissue in the body. Besides its primary function in movement and posture, skeletal muscle is a significant innate immune organ with the capacity to produce cytokines and chemokines... Read More about Chicken and duck myotubes are highly susceptible and permissive to influenza virus infection.

The effects of age upon the expression of three miRNAs in muscle stem cells isolated from two different porcine skeletal muscles (2014)
Journal Article
Redshaw, Z., Sweetman, D., & Loughna, P. (in press). The effects of age upon the expression of three miRNAs in muscle stem cells isolated from two different porcine skeletal muscles. Differentiation, 88(4-5), https://doi.org/10.1016/j.diff.2014.12.001

Aging is associated with a gradual loss of skeletal muscle mass and an impaired ability of this tissue to compensate for trauma. Studies in rodents and humans have also shown that resident stem cells within muscle have a reduced ability to proliferat... Read More about The effects of age upon the expression of three miRNAs in muscle stem cells isolated from two different porcine skeletal muscles.

Patterns of genome evolution that have accompanied host adaptation in Salmonella (2014)
Journal Article
Langridge, G. C., Fookes, M., Connor, T. R., Feltwell, T., Feasey, N., Parsons, B. N., …Thomson, N. R. (2015). Patterns of genome evolution that have accompanied host adaptation in Salmonella. Proceedings of the National Academy of Sciences, 112(3), 863-868. https://doi.org/10.1073/pnas.1416707112

Many bacterial pathogens are specialized, infecting one or few hosts, and this is often associated with more acute disease presentation. Specific genomes show markers of this specialization, which often reflect a balance between gene acquisition and... Read More about Patterns of genome evolution that have accompanied host adaptation in Salmonella.

Variation in the inter-service intervals of UK dairy cows (2014)
Journal Article
Remnant, J., Green, M. J., Huxley, J., & Hudson, C. (2015). Variation in the inter-service intervals of UK dairy cows. Journal of Dairy Science, 98(2), https://doi.org/10.3168/jds.2014-8366

An understanding of the normal estrous cycle length of the cow is important when managing and monitoring dairy herd fertility. Whilst the normal inter-ovulatory interval is widely considered to be 21 days, some studies have found alternative interval... Read More about Variation in the inter-service intervals of UK dairy cows.

Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs (2014)
Journal Article
Naqid, I. A., Owen, J. P., Maddison, B. C., Gardner, D. S., Foster, N., Tchorzewska, M., …Gough, K. C. (2015). Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs. Animal Feed Science and Technology, 201, 57-65. https://doi.org/10.1016/j.anifeedsci.2014.12.005

Salmonellosis causes significant economic losses to the pig industry and contaminated pork products are an important source of Salmonella for humans. The EU ban on the use of antibiotic growth promoters in pig production, and the emergence of antibio... Read More about Prebiotic and probiotic agents enhance antibody-based immune responses to Salmonella Typhimurium infection in pigs.

An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom (2014)
Journal Article
Bradley, A., Breen, J., Payne, B., White, V., & Green, M. (2015). An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom. Journal of Dairy Science, 98(3), https://doi.org/10.3168/jds.2014-8332

Vaccination can play a useful role in mastitis control programs, although there is a relative dearth of large, well-controlled field efficacy studies. This paper presents the findings on the use of a commercially available vaccine (Startvac, Hipra UK... Read More about An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom.

Influence of 1?, 25-dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes (2014)
Journal Article
Hdud, I. M., & Loughna, P. (2014). Influence of 1?, 25-dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes. Journal of Animal Science and Technology, 56, Article 33. https://doi.org/10.1186/s40781-014-0033-1

Background Sox 9 is a major marker of chondrocyte differentiation. When chondrocytes are cultured in vitro they progressively de-differentiate and this is associated with a decline in Sox 9 expression. The active form of vitamin D, 1, 25 (OH)2D3... Read More about Influence of 1?, 25-dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes.

Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field (2014)
Journal Article
Rauch, C., & Leigh, J. A. (in press). Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field. BBA - General Subjects, 1850(4), https://doi.org/10.1016/j.bbagen.2014.12.004

Background: Electroporation is a method of choice to transform living cells. The ability of electroporation to transfer small or large chemicals across the lipid bilayer membrane of eukaryotic cells or Gram-negative bacteria relies on the formation o... Read More about Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field.

Prioritisation of wildlife pathogens to be targeted in European surveillance programmes: expert-based risk analysis focus on ruminants (2014)
Journal Article
Ciliberti, A., Gavier-Widén, D., Yon, L., Hutchings, M. R., & Artois, M. (2015). Prioritisation of wildlife pathogens to be targeted in European surveillance programmes: expert-based risk analysis focus on ruminants. Preventive Veterinary Medicine, 118(4), https://doi.org/10.1016/j.prevetmed.2014.11.021

This study attempted to develop a list of priority pathogens. It is part of a European Union (EU) project dedicated to the surveillance of emerging or re-emerging pathogens of wildlife. Partners of the consortium established an initial list of 138 pa... Read More about Prioritisation of wildlife pathogens to be targeted in European surveillance programmes: expert-based risk analysis focus on ruminants.

Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses (2014)
Journal Article
Kuchipudi, S. V., Tellabati, M., Sebastian, S., Londt, B. Z., Jansen, C., Vervelde, L., …Chang, K. (2014). Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses. Veterinary Research, 45(1), Article 118. https://doi.org/10.1186/s13567-014-0118-3

© 2014 Kuchipudi et al.; licensee BioMed Central Ltd. Highly pathogenic avian influenza (HPAI) H5N1 viruses cause severe infection in chickens at near complete mortality, but corresponding infection in ducks is typically mild or asymptomatic. To unde... Read More about Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses.

Diagnostic testing in first opinion small animal consultations (2014)
Journal Article
Robinson, N. J., Dean, R. S., Cobb, M., & Brennan, M. L. (2015). Diagnostic testing in first opinion small animal consultations. Veterinary Record, 176(7), 174-174. https://doi.org/10.1136/vr.102786

DIAGNOSTIC testing is a vital part of the decision-making process, which aims to increase diagnostic certainty, assist management and treatment decisions and provide a prognosis (Radostits and others 2000). A wide range of tests are available, with v... Read More about Diagnostic testing in first opinion small animal consultations.

Analysis of interaction between the apicomplexan protozoan Toxoplasma gondii and host cells using label-free Raman spectroscopy (2014)
Journal Article
Naemat, A., Elsheikha, H. M., Al-sandaqchib, A., Kong, K., Ghita, A., & Notingher, I. (2015). Analysis of interaction between the apicomplexan protozoan Toxoplasma gondii and host cells using label-free Raman spectroscopy. Analyst, 140(3), 756-764. https://doi.org/10.1039/c4an01810a

Label-free imaging using Raman micro-spectroscopy (RMS) was used to characterize the spatio-temporal molecular changes of T. gondii tachyzoites and their host cell microenvironment. Raman spectral maps were recorded from isolated T. gondii tachyzoite... Read More about Analysis of interaction between the apicomplexan protozoan Toxoplasma gondii and host cells using label-free Raman spectroscopy.

Adaptive Management and the Value of Information: Learning Via Intervention in Epidemiology (2014)
Journal Article
Shea, K., Tildesley, M. J., Runge, M. C., Fonnesbeck, C. J., & Ferrari, M. J. (2014). Adaptive Management and the Value of Information: Learning Via Intervention in Epidemiology. PLoS Biology, 12(10), https://doi.org/10.1371/journal.pbio.1001970

Optimal intervention for disease outbreaks is often impeded by severe scientific uncertainty. Adaptive management (AM), long-used in natural resource management, is a structured decision-making approach to solving dynamic problems that accounts for t... Read More about Adaptive Management and the Value of Information: Learning Via Intervention in Epidemiology.

Physics of nail conditions: why do ingrown nails always happen in the big toes? (2014)
Journal Article
Rauch, C., & Cherkaoui-Rbati, M. (2014). Physics of nail conditions: why do ingrown nails always happen in the big toes?. Physical Biology, 11(6), Article 066004. https://doi.org/10.1088/1478-3975/11/6/066004

Although surgical treatment of nail conditions can be traced back centuries to the writings of Paul Aegineta (625–690 AC), little is known about the physical laws governing nail growth. Such a poor understanding together with the increasing number of... Read More about Physics of nail conditions: why do ingrown nails always happen in the big toes?.

High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance (2014)
Journal Article
Seng, L., Daly, J. M., Chang, K., & Kuchipudi, S. V. (2014). High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance. PLoS ONE, 9, Article e109023. https://doi.org/10.1371/journal.pone.0109023

Respiratory epithelial cells play a key role in influenza A virus (IAV) pathogenesis and host innate response. Transformed human respiratory cell lines are widely used in the study of IAV?host interactions due to their relative convenience, and inher... Read More about High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance.

A case of feline gastrointestinal eosinophilic sclerosing fibroplasia associated with phycomycetes (2014)
Journal Article
Grau-Roma, L., Galindo-Cardiel, I., Isidoro-Ayza, M., Fernández, M., & Majó, N. (2014). A case of feline gastrointestinal eosinophilic sclerosing fibroplasia associated with phycomycetes. Journal of Comparative Pathology, 151(4), https://doi.org/10.1016/j.jcpa.2014.08.005

Feline gastrointestinal eosinophilic sclerosing fibroplasia (FGESF) is a recently described inflammatory condition of domestic cats with unknown aetiology. A proportion of cases of FGESF are associated with bacteria, but antibiotic treatment is ineff... Read More about A case of feline gastrointestinal eosinophilic sclerosing fibroplasia associated with phycomycetes.

Quantitative trait loci mapping for canine hip dysplasia and its related traits in UK Labrador Retriever (2014)
Journal Article
Sánchez-Molano, E., Woolliams, J. A., Pong-Wong, R., Clements, D. N., Blott, S., & Wiener, P. (2014). Quantitative trait loci mapping for canine hip dysplasia and its related traits in UK Labrador Retriever. BMC Genomics, 15(1), Article 833. https://doi.org/10.1186/1471-2164-15-833

Background Canine hip dysplasia (CHD) is characterised by a malformation of the hip joint, leading to osteoarthritis and lameness. Current breeding schemes against CHD have resulted in measurable but moderate responses. The application of marker-ass... Read More about Quantitative trait loci mapping for canine hip dysplasia and its related traits in UK Labrador Retriever.

The application of eDNA for monitoring of the great crested newt in the UK (2014)
Journal Article
Rees, H. C., Bishop, K., Middleditch, D. J., Patmore, J. R., Maddison, B. C., & Gough, K. C. (2014). The application of eDNA for monitoring of the great crested newt in the UK. Ecology and Evolution, 4(21), https://doi.org/10.1002/ece3.1272

Current ecological surveys for great crested newts are time-consuming and expensive and can only be carried out within a short survey window. Additional survey methods which would facilitate the detection of rare or protected species such as the grea... Read More about The application of eDNA for monitoring of the great crested newt in the UK.