Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer
(2014)
Journal Article
Aljaberi, A. M., Webster, J. R., & Wheatley, S. P. (in press). Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer. Cancer Cell International, 14, Article 78. https://doi.org/10.1186/s12935-014-0078-8
Background Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essentia... Read More about Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer.