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Germ-line and somatic DICER1 mutations in pineoblastoma (2014)
Journal Article
de Kock, L., Sabbaghian, N., Druker, H., Weber, E., Hamel, N., Miller, S., …Foulkes, W. D. (2014). Germ-line and somatic DICER1 mutations in pineoblastoma. Acta Neuropathologica, 128(4), 583–595. https://doi.org/10.1007/s00401-014-1318-7

Germ-line RB-1 mutations predispose to pineoblastoma (PinB), but other predisposing genetic factors are not well established. We recently identified a germ-line DICER1 mutation in a child with a PinB. This was accompanied by loss of heterozygosity (L... Read More about Germ-line and somatic DICER1 mutations in pineoblastoma.