Skip to main content

Research Repository

Advanced Search

All Outputs (4)

Alterations in effective connectivity anchored on the insula in major depressive disorder (2014)
Journal Article
Iwabuchi, S. J., Peng, D., Fang, Y., Jiang, K., Liddle, E. B., Liddle, P. F., & Palaniyappan, L. (2014). Alterations in effective connectivity anchored on the insula in major depressive disorder. European Neuropsychopharmacology, 24(11), 1784-1792. doi:10.1016/j.euroneuro.2014.08.005

Recent work has identified disruption of several brain networks involving limbic and cortical regions that contribute to the generation of diverse symptoms of major depressive disorder (MDD). Of particular interest are the networks anchored on the ri... Read More about Alterations in effective connectivity anchored on the insula in major depressive disorder.

Structural connectivity of the salience-executive loop in schizophrenia (2014)
Journal Article
Iwabuchi, S. J., Liddle, P., & Palaniyappan, L. (2015). Structural connectivity of the salience-executive loop in schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, 265(2), 163-166. doi:10.1007/s00406-014-0547-z

Previously, differences have been shown in effective connectivity of the salience network between healthy controls and patients with schizophrenia. Specifically, the right anterior insula (rAI) fails to modulate the dorsolateral prefrontal cortex (DL... Read More about Structural connectivity of the salience-executive loop in schizophrenia.

Biological vulnerability to depression: Linked structural and functional brain network findings (2014)
Journal Article
Worwood, G., Nixon, E., Palaniyappan, L., Nixon, N. L., Liddle, P. F., Nixon, N. L., …Palaniyappan, L. (2014). Biological vulnerability to depression: Linked structural and functional brain network findings. British Journal of Psychiatry, 204(4), 283-289. https://doi.org/10.1192/bjp.bp.113.129965

Background: Patients in recovery following episodes of major depressive disorder (MDD) remain highly vulnerable to future recurrence. Although psychological determinants of this risk are well established, little is known about associated biological m... Read More about Biological vulnerability to depression: Linked structural and functional brain network findings.

Abnormalities in structural covariance of cortical gyrification in schizophrenia (2014)
Journal Article
Palaniyappan, L., Park, B., Balain, V., Dang, R., & Liddle, P. (2015). Abnormalities in structural covariance of cortical gyrification in schizophrenia. Brain Structure and Function, 220, 2059-2071. https://doi.org/10.1007/s00429-014-0772-2

The highly convoluted shape of the adult human brain results from several well-coordinated maturational events that start from embryonic development and extend through the adult life span. Disturbances in these maturational events can result in vario... Read More about Abnormalities in structural covariance of cortical gyrification in schizophrenia.