All Outputs (3)

STAT3 paradoxically stimulates ??catenin expression but inhibits ??catenin function (2014)
Journal Article
Ibrahem, S., Al‐Ghamdi, S., Baloch, K., Muhammad, B., Fadhil, W., Jackson, D., …Ilyas, M. (2014). STAT3 paradoxically stimulates β‐catenin expression but inhibits β‐catenin function. International Journal of Experimental Pathology, 95(6), 392-400. https://doi.org/10.1111/iep.12102

Wnt signalling and the signal transducer and activator of transcription 3 (STAT3) are oncogenic signalling pathways which are deregulated in colorectal cancer (CRC). Here we investigated the interaction of these two pathways. Firstly, we investigated... Read More about STAT3 paradoxically stimulates ??catenin expression but inhibits ??catenin function.

DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy (2014)
Journal Article
Fadhil, W., Kindle, K., Jackson, D., Zaitoun, A. M., Lane, N., Robins, A., & Ilyas, M. (2014). DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy. International Journal of Experimental Pathology, 95(1), https://doi.org/10.1111/iep.12070

Colorectal cancers (CRC) are thought to have genetic instability in the form of either microsatellite instability (MSI) or chromosomal instability (CIN). Recently, tumours have been described without either MSI or CIN, that is, microsatellite and chr... Read More about DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy.

A novel polar space random field model for the detection of glandular structures (2014)
Journal Article
Fu, H., Qiu, G., Shu, J., & Ilyas, M. (2014). A novel polar space random field model for the detection of glandular structures. IEEE Transactions on Medical Imaging, 33(3), 764-776. https://doi.org/10.1109/TMI.2013.2296572

In this paper, we propose a novel method to detect glandular structures in microscopic images of human tissue. We first convert the image from Cartesian space to polar space and then introduce a novel random field model to locate the possible boundar... Read More about A novel polar space random field model for the detection of glandular structures.