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All Outputs (18)

Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5 (2014)
Journal Article
Orton, E., Kendrick, D., West, J., & Tata, L. J. (2014). Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5. PLoS ONE, 9(10), Article e111631. https://doi.org/10.1371/journal.pone.0111631

BACKGROUND: Injury is a significant cause of childhood death and can result in substantial long-term disability. Injuries are more common in children from socio-economically deprived families, contributing to health inequalities between the most and... Read More about Persistence of health inequalities in childhood injury in the UK: a population-based cohort study of children under 5.

Limited risks of major congenital anomalies in children of mothers with coeliac disease: a population-based cohort study (2014)
Journal Article
Ban, L., West, J., Abdul Sultan, A., Dhalwani, N. N., Ludvigsson, J. F., & Tata, L. J. (in press). Limited risks of major congenital anomalies in children of mothers with coeliac disease: a population-based cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 122(13), https://doi.org/10.1111/1471-0528.13102

Objective: To examine major congenital anomaly (CA) risks in children of mothers with coeliac disease (CD) compared with mothers without CD. Design: Population-based cohort study. Setting: Linked maternal–child medical records from a large pr... Read More about Limited risks of major congenital anomalies in children of mothers with coeliac disease: a population-based cohort study.

The incidence of other gastroenterological disease following diagnosis of irritable bowel syndrome in the UK: a cohort study (2014)
Journal Article
Canavan, C., Card, T. R., & West, J. (2014). The incidence of other gastroenterological disease following diagnosis of irritable bowel syndrome in the UK: a cohort study. PLoS ONE, 9(9), Article e106478. https://doi.org/10.1371/journal.pone.0106478

BACKGROUND: Guidelines recommend Irritable Bowel Syndrome (IBS) diagnosis and management in primary care with minimal investigations; however little evidence exists regarding risk of organic gastrointestinal conditions following diagnosis of IBS and... Read More about The incidence of other gastroenterological disease following diagnosis of irritable bowel syndrome in the UK: a cohort study.

Review article: the economic impact of the irritable bowel syndrome (2014)
Journal Article
Canavan, C., West, J., & Card, T. R. (in press). Review article: the economic impact of the irritable bowel syndrome. Alimentary Pharmacology and Therapeutics, 40(9), https://doi.org/10.1111/apt.12938

Background: Irritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal system affecting a large number of people worldwide. Whilst it has no attributable mortality, it has substantial impact on patients' quality of life (... Read More about Review article: the economic impact of the irritable bowel syndrome.

Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England (2014)
Journal Article
Abdul Sultan, A., Grainge, M. J., West, J., Fleming, K. M., Nelson-Piercy, C., & Tata, L. J. (in press). Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England. Blood, 124(18), https://doi.org/10.1182/blood-2014-05-572834

For women with preeclampsia, BMI >30 kg/m2, infection, or those having cesarean delivery, VTE risk remained elevated for 6 weeks postpartum.For women with postpartum hemorrhage or preterm birth, the relative rate of VTE was only increased for the... Read More about Impact of risk factors on the timing of first postpartum venous thromboembolism: a population-based cohort study from England.

Women with celiac disease present with fertility problems no more often than women in the general population (2014)
Journal Article
Dhalwani, N. N., West, J., Sultan, A. A., Ban, L., & Tata, L. J. (in press). Women with celiac disease present with fertility problems no more often than women in the general population. Gastroenterology, 147(6), Article 1267-1274.e1. https://doi.org/10.1053/j.gastro.2014.08.025

BACKGROUND & AIMS: Studies have associated infertility with celiac disease. However, these included small numbers of women attending infertility specialist services and subsequently screened for celiac disease, and therefore may not have been represe... Read More about Women with celiac disease present with fertility problems no more often than women in the general population.

Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England (2014)
Journal Article
Abdul Sultan, A., Tata, L. J., Fleming, K. M., Crooks, C. J., Ludvigsson, J. F., Dhalwani, N. N., …West, J. (in press). Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England. American Journal of Gastroenterology, 109(10), https://doi.org/10.1038/ajg.2014.196

OBJECTIVES: Evidence-based information about adverse birth outcomes and pregnancy complications is crucial when counseling women with celiac disease (CD); however, limited population-based data on such risks exist. We estimated these for pregnant wom... Read More about Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England.

First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study (2014)
Journal Article
Ban, L., West, J., Gibson, J. E., Fiaschi, L., Sokal, R., Doyle, P., …Tata, L. J. (2014). First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study. PLoS ONE, 9(6), Article e100996. https://doi.org/10.1371/journal.pone.0100996

BACKGROUND: Despite their widespread use the effects of taking benzodiazepines and non-benzodiazepine hypnotics during pregnancy on the risk of major congenital anomaly (MCA) are uncertain. The objectives were to estimate absolute and relative risks... Read More about First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study.

Injury among children and young adults with epilepsy (2014)
Journal Article
Prasad, V., Kendrick, D., Sayal, K., Thomas, S. L., & West, J. (in press). Injury among children and young adults with epilepsy. Pediatrics, 133(5), https://doi.org/10.1542/peds.2013-2554

OBJECTIVE: To investigate whether children and young adults with epilepsy are at a greater risk of fracture, thermal injury, or poisoning than those without. METHODS: A cohort study was conducted by using the Clinical Practice Research Datalink (198... Read More about Injury among children and young adults with epilepsy.

Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study (2014)
Journal Article
West, J., Fleming, K. M., Tata, L. J., Card, T. R., & Crooks, C. J. (2014). Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study. American Journal of Gastroenterology, 109(5), 757-768. https://doi.org/10.1038/ajg.2014.55

OBJECTIVES: Few studies have quantified the incidence and prevalence of celiac disease (CD) and dermatitis herpetiformis (DH) nationally and regionally by time and age groups. Understanding this epidemiology is crucial for hypothesizing about causes... Read More about Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study.

Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study (2014)
Journal Article
Ban, L., Gibson, J. E., West, J., Fiaschi, L., Sokal, R., Smeeth, L., …Tata, L. J. (in press). Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 121(12), https://doi.org/10.1111/1471-0528.12682

OBJECTIVE: To estimate risks of major congenital anomaly (MCA) among children of mothers prescribed antidepressants during early pregnancy or diagnosed with depression but without antidepressant prescriptions. DESIGN: Population-based cohort study.... Read More about Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study.

Venous thromboembolism in children with cancer – a population-based cohort study (2014)
Journal Article
Walker, A. J., Grainge, M. J., Card, T. R., West, J., Ranta, S., & Ludvigsson, J. F. (2014). Venous thromboembolism in children with cancer – a population-based cohort study. Thrombosis Research, 133(3), https://doi.org/10.1016/j.thromres.2013.12.021

Introduction: Cancer is a known risk factor for venous thromboembolism (VTE) in adults, but population-based data in children are scarce. Materials and methods: We conducted a cohort study utilising linkage of the Clinical Practice Research Datab... Read More about Venous thromboembolism in children with cancer – a population-based cohort study.

Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England (2014)
Journal Article
Walker, A., West, J., Card, T. R., Humes, D., & Grainge, M. J. (2014). Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England. Journal of Thrombosis and Haemostasis, 12(5), https://doi.org/10.1111/jth.12533

BACKGROUND: Patients with colorectal cancer are at high risk of developing venous thromboembolism (VTE), and recent international guidelines have advised extended prophylaxis for some of these patients following surgery or during chemotherapy. Howeve... Read More about Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England.

The epidemiology of irritable bowel syndrome (2014)
Journal Article
Canavan, C., West, J., & Card, T. R. (2014). The epidemiology of irritable bowel syndrome. Clinical Epidemiology, 6, https://doi.org/10.2147/CLEP.S40245

Irritable bowel syndrome (IBS) is a functional condition of the bowel that is diagnosed using clinical criteria. This paper discusses the nature of the diagnostic process for IBS and how this impacts epidemiological measurements. Depending on the dia... Read More about The epidemiology of irritable bowel syndrome.

1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study (2014)
Journal Article
Ratib, S., Fleming, K. M., Crooks, C. J., Aithal, G. P., & West, J. (2014). 1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study. Journal of Hepatology, 60(2), https://doi.org/10.1016/j.jhep.2013.09.027

BACKGROUND & AIMS: Large, population-based studies that have included the full spectrum of cirrhosis estimating survival, taking into account time-at-risk are lacking. We aimed to report 1- and 5-year average survival rates for people with cirrhosis... Read More about 1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study.

Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer (2014)
Journal Article
Ratib, S., West, J., Crooks, C. J., & Fleming, K. M. (2014). Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer. American Journal of Gastroenterology, 109(2), https://doi.org/10.1038/ajg.2013.405

OBJECTIVES: There is no routine registration of the occurrence of newly diagnosed cases of cirrhosis in the United Kingdom. This study seeks to determine precise estimates and trends of the incidence of cirrhosis in England, and directly compare the... Read More about Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer.

How to read a cohort study (2014)
Book Chapter
Tata, L. J. (2014). How to read a cohort study. In N. J. Talley, G. Richard Locke III, P. Moayyedi, J. West, & Y. A. Saito (Eds.), GI Epidemiology: Diseases and Clinical Methodology (15-29). (Second). John Wiley & Sons, Ltd. https://doi.org/10.1002/9781118727072.ch2

The cohort is the basis of all epidemiologic study designs as it is the closest way to study the natural progression of people's life course over which the temporal relationship between exposures and outcomes can be assessed. Although a cohort is def... Read More about How to read a cohort study.