All Outputs (3)

Functionally Relevant White Matter Degradation in Multiple Sclerosis: A Tract-based Spatial Meta-Analysis (2014)
Journal Article
Welton, T., Kent, D., Constantinescu, C. S., Auer, D. P., & Dineen, R. A. (2015). Functionally Relevant White Matter Degradation in Multiple Sclerosis: A Tract-based Spatial Meta-Analysis. Radiology, 275(1), 89-96. https://doi.org/10.1148/radiol.14140925

Purpose To identify statistical consensus between published studies for distribution and functional relevance of tract white matter (WM) degradation in multiple sclerosis (MS). Materials and Methods By systematically searching online databases... Read More about Functionally Relevant White Matter Degradation in Multiple Sclerosis: A Tract-based Spatial Meta-Analysis.

Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era (2014)
Journal Article
Perry, C., Agarwal, D., Abdel-Fatah, T. M., Lourdusamy, A., Grundy, R., Auer, D. T., …Madhusudan, S. (2014). Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era. Oncotarget, 5(14), 5764-5781. https://doi.org/10.18632/oncotarget.2180

Deregulation of multiple DNA repair pathways may contribute to aggressive biology and therapy resistance in gliomas. We evaluated transcript levels of 157 genes involved in DNA repair in an adult glioblastoma Test set (n=191) and validated in ‘The Ca... Read More about Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era.

The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T (2014)
Journal Article
Schwarz, S., Afzal, M., Morgan, P., Auer, D., Bajaj, N., & Gowland, P. A. (2014). The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T. PLoS ONE, 9(4), Article e93814. https://doi.org/10.1371/journal.pone.0093814

There is no well-established in vivo marker of nigral degeneration in Parkinson's disease (PD). An ideal imaging marker would directly mirror the loss of substantia nigra dopaminergic neurones, which is most prominent in sub-regions called nigrosomes... Read More about The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T.