All Outputs (11)

Biomimetic Human Lung Models (2014)
Book Chapter
Harrington, H. C., Cato, P. A., & Ghaemmaghami, A. M. (2014). Biomimetic Human Lung Models. In Handbook of Biomimetics and Bioinspiration (1017-1036). World Scientific. https://doi.org/10.1142/9789814354936_0037

New strategies for the treatment of lung disease are being sought to combat the increased prevalence of lung disease within the developedworld.As researchmoves away from reliance upon the use of animal models in pre-clinical studies innovative method... Read More about Biomimetic Human Lung Models.

A hybrid PDMS/paper passive pump for slow-release/delivery of drugs in chronic dermal wounds (2014)
Conference Proceeding
Rahimi, R., Ochoa, M., Zhou, J., Tamayol, A., Dokmeci, M. R., Khademhosseini, A., …Ziaie, B. (2014). A hybrid PDMS/paper passive pump for slow-release/delivery of drugs in chronic dermal wounds. In Proceedings of 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (2205-2207)

© 14CBMS. In this paper, we present a hybrid PDMS/paper-based passive pump for slow drug delivery in chronic wounds. The pump consists of a PDMS microfluidic network that is irreversibly bonded to the polyethylene-coated (hydrophobic) side of a comme... Read More about A hybrid PDMS/paper passive pump for slow-release/delivery of drugs in chronic dermal wounds.

Surgical materials: Current challenges and nano-enabled solutions (2014)
Journal Article
Annabi, N., Tamayol, A., Shin, S. R., Ghaemmaghami, A. M., Peppas, N. A., & Khademhosseini, A. (2014). Surgical materials: Current challenges and nano-enabled solutions. Nano Today, 9(5), 574-589. https://doi.org/10.1016/j.nantod.2014.09.006

© 2014 Elsevier Ltd. All rights reserved. Surgical adhesive biomaterials have emerged as substitutes to sutures and staples in many clinical applications. Nano-enabled materials containing nanoparticles or having a distinct nanotopography have been u... Read More about Surgical materials: Current challenges and nano-enabled solutions.

Utilizing nanosensor-incorporated scaffolds in the development of a 3D lung model (2014)
Book Chapter
Harrington, H. C., Rose, F. R., Ghaemmaghami, A. M., & Aylott, J. W. (2014). Utilizing nanosensor-incorporated scaffolds in the development of a 3D lung model. In J. Haycock, A. Ahluwalia, & J. M. Wilkinson (Eds.), Cellular In Vitro Testing (89-107). Jenny Stanford Publishing

Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds (2014)
Journal Article
Morris, G., Bridge, J., Eltboli, O., Lewis, M., Knox, A., Aylott, J. W., …Rose, F. R. (2014). Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds. AJP - Lung Cellular and Molecular Physiology, 307(1), Article L38-L47. https://doi.org/10.1152/ajplung.00318.2013

Human airway smooth muscle (HASM) contraction plays a central role in regulating airway resistance in both healthy and asthmatic bronchioles. In vitro studies that investigate the intricate mechanisms that regulate this contractile process are predom... Read More about Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds.

A novel electrospun biphasic scaffold provides optimal three-dimensional topography forin vitroco-culture of airway epithelial and fibroblast cells (2014)
Journal Article
Morris, G., Bridge, J., Brace, L., Knox, A., Aylott, J. W., Brightling, C., …Rose, F. R. (2014). A novel electrospun biphasic scaffold provides optimal three-dimensional topography forin vitroco-culture of airway epithelial and fibroblast cells. Biofabrication, 6(3), Article 035014. https://doi.org/10.1088/1758-5082/6/3/035014

Conventional airway in vitro models focus upon the function of individual structural cells cultured in a two-dimensional monolayer, with limited three-dimensional (3D) models of the bronchial mucosa. Electrospinning offers an attractive method to pro... Read More about A novel electrospun biphasic scaffold provides optimal three-dimensional topography forin vitroco-culture of airway epithelial and fibroblast cells.

A janus-paper PDMS platform for lab-on-a-chip applications (2014)
Conference Proceeding
Rahimi, R., Ochoa, M., Parupudi, T., Donaldson, A., Dokmeci, M. R., Khademhosseini, A., …Ziaie, B. (2014). A janus-paper PDMS platform for lab-on-a-chip applications. In Solid-State Sensors, Actuators, and Microsystems Workshop (119-122). https://doi.org/10.31438/trf.hh2014.34

© 2014TRF. A commercially available Janus paper with one hydrophobic (polyethylene-coated) face and a hygroscopic/hydrophilic one is irreversibly bonded to a PDMS substrate incorporating microfluidic channels via corona discharge surface treatment. T... Read More about A janus-paper PDMS platform for lab-on-a-chip applications.

Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems (2014)
Book
Jabbari, E., Kim, D. H., Lee, L. P., Ghaemmaghami, A., & Khademhosseini, A. (2014). Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems. World Scientific. https://doi.org/10.1142/8169

Global warming, pollution, food and water shortage, cyberspace insecurity, over-population, land erosion, and an overburdened health care system are major issues facing the human race and our planet. These challenges have presented a mandate to devel... Read More about Handbook Of Biomimetics And Bioinspiration: Biologically-driven Engineering Of Materials, Processes, Devices, And Systems.

Front matter (2014)
Book Chapter
Jabbari, E., Kim, D. H., Lee, L. P., Ghaemmaghami, A., & Khademhosseini, A. (2014). Front matter. In E. Jabbari, D. Ho Kim, L. P. Lee, A. Ghaemmaghami, & A. Khademhosseini (Eds.), Handbook of Biomimetics and Bioinspiration: Biologically-driven Engineering of Materials, Processes, Devices, and Systems (i-lix). World Scientific. https://doi.org/10.1142/9789814354936_fmatter01

Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels (2014)
Journal Article
Bertassoni, L. E., Cardoso, J. C., Manoharan, V., Cristino, A. L., Bhise, N. S., Araujo, W. A., …Khademhosseini, A. (2015). Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels. Biofabrication, 6(2), 1-11. https://doi.org/10.1088/1758-5082/6/2/024105

Fabrication of three dimensional (3D) organoids with controlled microarchitectures has been shown to enhance tissue functionality. Bioprinting can be used to precisely position cells and cell-laden materials to generate controlled tissue architecture... Read More about Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels.

Immunocompetent 3D model of human upper airway for disease modeling and in vitro drug evaluation (2014)
Journal Article
Harrington, H., Cato, P., Salazar, F., Wilkinson, M., Knox, A., Haycock, J. W., …Ghaemmaghami, A. M. (2014). Immunocompetent 3D model of human upper airway for disease modeling and in vitro drug evaluation. Molecular Pharmaceutics, 11(7), 2082-2091. https://doi.org/10.1021/mp5000295

The development of more complex in vitro models for the assessment of novel drugs and chemicals is needed because of the limited biological relevance of animal models to humans as well as ethical considerations. Although some human-cell-based assays... Read More about Immunocompetent 3D model of human upper airway for disease modeling and in vitro drug evaluation.