Skip to main content

Research Repository

Advanced Search

All Outputs (1281)

The effect of feeding a low iron diet prior to and during gestation on fetal and maternal iron homeostasis in two strains of rat (2013)
Journal Article
Cornock, R., Gambling, L., Langley-Evans, S. C., McArdle, H. J., & McMullen, S. (2013). The effect of feeding a low iron diet prior to and during gestation on fetal and maternal iron homeostasis in two strains of rat. Reproductive Biology and Endocrinology, 11(32), Article 32. https://doi.org/10.1186/1477-7827-11-32

Background Iron deficiency anaemia during pregnancy is a global problem, with short and long term consequences for maternal and child health. Animal models have demonstrated that the developing fetus is vulnerable to maternal iron restriction, impac... Read More about The effect of feeding a low iron diet prior to and during gestation on fetal and maternal iron homeostasis in two strains of rat.

Insights into the structure and assembly of the Bacillus subtilis clamp-loader complex and its interaction with the replicative helicase. (2013)
Journal Article
Afonso, J. P., Chintakayala, K., Suwannachart, C., Sedelnikova, S., Giles, K., Hoyes, J. B., …Oldham, N. J. (2013). Insights into the structure and assembly of the Bacillus subtilis clamp-loader complex and its interaction with the replicative helicase. Nucleic Acids Research, 41(9), https://doi.org/10.1093/nar/gkt173

The clamp-loader complex plays a crucial role in DNA replication by loading the β-clamp onto primed DNA to be used by the replicative polymerase. Relatively little is known about the stoichiometry, structure and assembly pathway of this complex, an... Read More about Insights into the structure and assembly of the Bacillus subtilis clamp-loader complex and its interaction with the replicative helicase..

White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms (2013)
Journal Article
Paillère Martinot, M., Lemaitre, H., Artiges, E., Miranda, R., Goodman, R., Penttilä, J., …Martinot, J. (2014). White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms. Molecular Psychiatry, 19, 462-470. https://doi.org/10.1038/mp.2013.44

Abnormalities in white-matter (WM) microstructure, as lower fractional anisotropy (FA), have been reported in adolescent-onset bipolar disorder and in youth at familial risk for bipolarity. We sought to determine whether healthy adolescents with subt... Read More about White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms.

Participant experiences of mobile device-based diary studies (2013)
Journal Article
Sun, X., Golightly, D., Cranwell, J., Bedwell, B. D., & Sharples, S. (2013). Participant experiences of mobile device-based diary studies. International Journal of Mobile Human Computer Interaction, 5(2), https://doi.org/10.4018/jmhci.2013040104

Mobile device-based diary studies have potential as contextual data capture methods that address the limitations of the traditional paper-based diary method. While there have been a number of studies that demonstrate the power of the mobile device-ba... Read More about Participant experiences of mobile device-based diary studies.

Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study (2013)
Journal Article
Crooks, C. J., Card, T. R., & West, J. (2013). Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study. PLoS Medicine, 10(4), Article e1001437. https://doi.org/10.1371/journal.pmed.1001437

Background It is unclear whether an upper gastrointestinal bleed is an isolated gastrointestinal event or an indicator of a deterioration in a patient's overall health status. Therefore, we investigated the excess causes of death in individuals afte... Read More about Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study.

Resonant tunnelling and negative differential conductance in graphene transistors (2013)
Journal Article
Britnell, L., Gorbachev, R., Geim, A., Ponomarenko, L., Mishchenko, A., Greenaway, M., …Eaves, L. (2013). Resonant tunnelling and negative differential conductance in graphene transistors. Nature Communications, 4, Article 1794. https://doi.org/10.1038/ncomms2817

The chemical stability of graphene and other free-standing two-dimensional crystals means that they can be stacked in different combinations to produce a new class of functional materials, designed for specific device applications. Here we report res... Read More about Resonant tunnelling and negative differential conductance in graphene transistors.

SPROUTY2 is a ?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer (2013)
Journal Article
Ordóñez-Morán, P., Irmisch, A., Barbáchano, A., Chicote, I., Tenbaum, S., Landolfi, S., …Pálmer, H. G. (2014). SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer. Oncogene, 33(15), 1975-1985. https://doi.org/10.1038/onc.2013.140

SPROUTY2 (SPRY2) is an intracellular regulator of receptor tyrosine kinase signaling involved in cell growth, differentiation and tumorigenesis. Here, we show that SPRY2 is a target gene of the Wnt/?-catenin pathway that is abnormally activated in mo... Read More about SPROUTY2 is a ?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer.

Accelerating fibre orientation estimation from diffusion weighted magnetic resonance imaging using GPUs (2013)
Journal Article
Hernández, M., Guerrero, G. D., Cecilia, J. M., García, J. M., Inuggi, A., Jbabdi, S., …Sotiropoulos, S. N. (2013). Accelerating fibre orientation estimation from diffusion weighted magnetic resonance imaging using GPUs. PLoS ONE, 8(4), Article e61892. https://doi.org/10.1371/journal.pone.0061892

With the performance of central processing units (CPUs) having effectively reached a limit, parallel processing offers an alternative for applications with high computational demands. Modern graphics processing units (GPUs) are massively parallel pro... Read More about Accelerating fibre orientation estimation from diffusion weighted magnetic resonance imaging using GPUs.

Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model (2013)
Journal Article
Ivell, R., Dai, Y., Mann, N., & Anand-Ivell, R. (2014). Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model. Molecular and Cellular Endocrinology, 382(1), https://doi.org/10.1016/j.mce.2013.04.016

Steroidogenic tissues such as the ovary, testes or adrenal glands are paradoxical in that they often indicate actions of steroid hormones within a dynamic range of ligand concentration in a high nanomolar or even micromolar level, i.e. at the natural... Read More about Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model.

“We wouldn’t of made friends if we didn’t come to Football United”: the impacts of a football program on young people’s peer, prosocial and cross-cultural relationships (2013)
Journal Article
Nathan, S., Kemp, L., Bunde-Birouste, A., MacKenzie, J., Evers, C., & Shwe, T. A. (2013). “We wouldn’t of made friends if we didn’t come to Football United”: the impacts of a football program on young people’s peer, prosocial and cross-cultural relationships. BMC Public Health, 13, Article 399. https://doi.org/10.1186/1471-2458-13-399

Background Sport as a mechanism to build relationships across cultural boundaries and to build positive interactions among young people has often been promoted in the literature. However, robust evaluation of sport-for-development program impact... Read More about “We wouldn’t of made friends if we didn’t come to Football United”: the impacts of a football program on young people’s peer, prosocial and cross-cultural relationships.

Tailored scenarios: a low-cost online method to elicit perceptions on designs using real relationships (2013)
Conference Proceeding
Coughlan, T., Brown, M., Lawson, G., Mortier, R., Houghton, R., & Goulden, M. (2013). Tailored scenarios: a low-cost online method to elicit perceptions on designs using real relationships.

This paper describes the on-going development of a method to elicit perceptions of design ideas for social technologies, through automatically tailoring scenarios presented in online surveys using information gathered from respondents. The work has b... Read More about Tailored scenarios: a low-cost online method to elicit perceptions on designs using real relationships.

Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs (2013)
Journal Article
Hirt, B. V., Wattis, J. A., & Preston, S. P. (2014). Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs. Journal of Mathematical Biology, 68(6), 1521-1552. https://doi.org/10.1007/s00285-013-0678-2

Telomeres are guanine-rich sequences at the end of chromosomes which shorten during each replication event and trigger cell cycle arrest and/or controlled death (apoptosis) when reaching a threshold length. The enzyme telomerase replenishes the ends... Read More about Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs.

Using hormones to manage dairy cow fertility: the clinical and ethical beliefs of veterinary practitioners (2013)
Journal Article
Higgins, H. M., Ferguson, E., Smith, R. F., & Green, M. J. (2013). Using hormones to manage dairy cow fertility: the clinical and ethical beliefs of veterinary practitioners. PLoS ONE, 8(4), Article 9. https://doi.org/10.1371/journal.pone.0062993

In the face of a steady decline in dairy cow fertility over several decades, using hormones to assist reproduction has become common. In the European Union, hormones are prescription-only medicines, giving veterinary practitioners a central role in t... Read More about Using hormones to manage dairy cow fertility: the clinical and ethical beliefs of veterinary practitioners.

A novel grass hybrid to reduce flood generation in temperate regions (2013)
Journal Article
Macleod, C. J. A., Humphreys, M. W., Whalley, W. R., Turner, L., Binley, A., Watts, C. W., …Haygarth, P. M. (2013). A novel grass hybrid to reduce flood generation in temperate regions. Scientific Reports, 3(1), 1-7. https://doi.org/10.1038/srep01683

We report on the evaluation of a novel grass hybrid that provides efficient forage production and could help mitigate flooding. Perennial ryegrass (Lolium perenne) is the grass species of choice for most farmers, but lacks resilience against extremes... Read More about A novel grass hybrid to reduce flood generation in temperate regions.

Hyperglycaemia promotes cerebral barrier dysfunction through activation of protein kinase C-? (2013)
Journal Article
Shao, B., & Bayraktutan, U. (2013). Hyperglycaemia promotes cerebral barrier dysfunction through activation of protein kinase C-?. Diabetes, Obesity and Metabolism, 15(11), 993-999. https://doi.org/10.1111/dom.12120

Aim: To examine whether protein kinase C (PKC) and associated downstream mechanisms are involved in hyperglycaemia (HG)-evoked blood-brain barrier (BBB) damage. Methods: The activities of total PKC (Peptag assay), NADPH oxidase (lucigenin assay) and... Read More about Hyperglycaemia promotes cerebral barrier dysfunction through activation of protein kinase C-?.

Synthesis and in vitro and in vivo characterization of highly ?1-Selective ?-Adrenoceptor partial agonists (2013)
Journal Article
Mistry, S. N., Baker, J. G., Fischer, P. M., Hill, S. J., Gardiner, S. M., & Kellam, B. (2013). Synthesis and in vitro and in vivo characterization of highly ?1-Selective ?-Adrenoceptor partial agonists. Journal of Medicinal Chemistry, 56(10), https://doi.org/10.1021/jm400348g

β-Adrenoceptor antagonists boast a 50-year use for symptomatic control in numerous cardiovascular diseases. One might expect highly selective antagonists are available for the human β-adrenoceptor subtype involved in these diseases, yet few truly β1-... Read More about Synthesis and in vitro and in vivo characterization of highly ?1-Selective ?-Adrenoceptor partial agonists.

Analysis of Vertical Strip Wound Fault-Tolerant Permanent Magnet Synchronous Machines (2013)
Journal Article
Arumugam, P., Hamiti, T., Brunson, C., & Gerada, C. (2014). Analysis of Vertical Strip Wound Fault-Tolerant Permanent Magnet Synchronous Machines. IEEE Transactions on Industrial Electronics, 61(3), 1158-1168. https://doi.org/10.1109/TIE.2013.2259777

This paper investigates the behavior of a vector-controlled fault-tolerant permanent magnet motor drive system adopting a vertically placed strip winding (VSW) which can limit interturn short-circuit (SC) fault current to its rated value regardless o... Read More about Analysis of Vertical Strip Wound Fault-Tolerant Permanent Magnet Synchronous Machines.