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Genome-wide methylation and gene expression changes in newborn rats following maternal protein restriction and reversal by folic acid (2013)
Journal Article
Altobelli, G., Bogdarina, I., Stupka, E., Clark, A. J., & Langley-Evans, S. C. (2013). Genome-wide methylation and gene expression changes in newborn rats following maternal protein restriction and reversal by folic acid. PLoS ONE, 8, Article e82989. https://doi.org/10.1371/journal.pone.0082989

A large body of evidence from human and animal studies demonstrates that the maternal diet during pregnancy can programme physiological and metabolic functions in the developing fetus, effectively determining susceptibility to later disease. The mech... Read More about Genome-wide methylation and gene expression changes in newborn rats following maternal protein restriction and reversal by folic acid.

Exposure of neonatal rats to maternal cafeteria feeding during suckling alters hepatic gene expression and DNA methylation in the insulin signalling pathway (2013)
Journal Article
Daniel, Z., Akyol, A., McMullen, S., & Langley-Evans, S. C. (2013). Exposure of neonatal rats to maternal cafeteria feeding during suckling alters hepatic gene expression and DNA methylation in the insulin signalling pathway. Genes and Nutrition, 9(1), Article 365. https://doi.org/10.1007/s12263-013-0365-3

Nutrition in early life is a determinant of lifelong physiological and metabolic function. Diseases that are associated with ageing may, therefore, have their antecedents in maternal nutrition during pregnancy and lactation. Rat mothers were fed eith... Read More about Exposure of neonatal rats to maternal cafeteria feeding during suckling alters hepatic gene expression and DNA methylation in the insulin signalling pathway.

Neuromuscular electrical stimulation of the quadriceps in patients with non-small cell lung cancer receiving palliative chemotherapy: a randomized Phase II study (2013)
Journal Article
Lucia, A., Maddocks, M., Halliday, V., Chauhan, A., Taylor, V., Nelson, A., …Wilcock, A. (2013). Neuromuscular electrical stimulation of the quadriceps in patients with non-small cell lung cancer receiving palliative chemotherapy: a randomized Phase II study. PLoS ONE, 8(12), Article e86059. https://doi.org/10.1371/journal.pone.0086059

Background A reduced exercise capacity is associated with increased morbidity and mortality in patients with advanced non-small cell lung cancer (NSCLC). Therapeutic exercise can be beneficial and neuromuscular electrical stimulation (NMES) of the... Read More about Neuromuscular electrical stimulation of the quadriceps in patients with non-small cell lung cancer receiving palliative chemotherapy: a randomized Phase II study.

Mathematical analysis of a model for the growth of the bovine corpus luteum (2013)
Journal Article
Prokopiou, S. A., Byrne, H. M., Jeffrey, M. R., Robinson, R. S., Mann, G. E., & Owen, M. R. (2014). Mathematical analysis of a model for the growth of the bovine corpus luteum. Journal of Mathematical Biology, 69, 1515-1546. https://doi.org/10.1007/s00285-013-0722-2

© 2013, Springer-Verlag Berlin Heidelberg. The corpus luteum (CL) is an ovarian tissue that grows in the wound space created by follicular rupture. It produces the progesterone needed in the uterus to maintain pregnancy. Rapid growth of the CL and pr... Read More about Mathematical analysis of a model for the growth of the bovine corpus luteum.

Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides (2013)
Journal Article
Smith, I. H., Lawson, C. J., Harding, S. E., Gahler, R. J., Lyon, M. R., & Wood, S. (2014). Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides. Food Hydrocolloids, 38, https://doi.org/10.1016/j.foodhyd.2013.12.004

Viscosity development with time was studied during the aqueous dissolution of the novel polysaccharide complex PGX®, a finer particle size version used in meal replacement PGXf, and a blend of the three polysaccharides 3PB used in their manufacture.... Read More about Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides.

Quantification of changes in zero valent iron morphology using X-ray computed tomography (2013)
Journal Article
Luo, P., Bailey, E. H., & Mooney, S. J. (2013). Quantification of changes in zero valent iron morphology using X-ray computed tomography. Journal of Environmental Sciences, 25(11), 2344-2351. https://doi.org/10.1016/S1001-0742%2812%2960237-X

Morphological changes within the porous architecture of laboratory scale zero valent iron (ZVI) permeable reactive barriers (PRBs), after exposure to different groundwater conditions, have been quantified experimentally for different ZVI/sand ratios... Read More about Quantification of changes in zero valent iron morphology using X-ray computed tomography.

Complete genome sequence of universal bacteriophage host strain Campylobacter jejuni subsp. jejuni PT14 (2013)
Journal Article
Brathwaite, K. J., Siringan, P., Moreton, J., Wilson, R., & Connerton, I. F. (2013). Complete genome sequence of universal bacteriophage host strain Campylobacter jejuni subsp. jejuni PT14. Genome Announcements, 1(6), 1-2. https://doi.org/10.1128/genomea.00969-13

Campylobacter jejuni strain PT14 is a clinical isolate previously used to propagate bacteriophages in the United Kingdom phage typing scheme. The strain has proven useful in the isolation of Campylobacter bacteriophages from several sources, and it f... Read More about Complete genome sequence of universal bacteriophage host strain Campylobacter jejuni subsp. jejuni PT14.

The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages (2013)
Journal Article
Warneke, W., Klaus, S., Fink, H., Langley-Evans, S. C., & Voigt, J. (2014). The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages. Pharmacology Biochemistry and Behavior, 116, https://doi.org/10.1016/j.pbb.2013.11.016

There is emerging experimental evidence that hyper-energetic diets not only cause obesity but also impact on behaviour in rodents. A hyper-energetic comfort diet/cafeteria diet (CD) fed during early development programmes anxiety-related behaviour in... Read More about The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages.

A female-emitted pheromone component is associated with reduced male courtship in the parasitoid wasp Spalangia endius (2013)
Journal Article
Mowles, S. L., King, B. H., Linforth, R. S., & Hardy, I. C. (2013). A female-emitted pheromone component is associated with reduced male courtship in the parasitoid wasp Spalangia endius. PLoS ONE, 8(11), Article e82010. https://doi.org/10.1371/journal.pone.0082010

During courtship interactions, the courted individual may not always be prepared to mate. For example, mating or courtship may be detrimental to its fitness and resistance is expected under these circumstances. As such, various resistance strategies... Read More about A female-emitted pheromone component is associated with reduced male courtship in the parasitoid wasp Spalangia endius.

Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain (2013)
Journal Article
Kelly, S., Chapman, R., Woodhams, S., Sagar, D. R., Turner, J., Burston, J., …Chapman, V. (2014). Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain. Annals of the Rheumatic Diseases, 74, https://doi.org/10.1136/annrheumdis-2013-203413

Objectives Blockade of transient receptor potential vanilloid 1 (TRPV1) with systemic antagonists attenuates osteoarthritis (OA) pain behaviour in rat models, but on-target-mediated hyperthermia has halted clinical trials. The present study investiga... Read More about Increased function of pronociceptive TRPV1 at the level of the joint in a rat model of osteoarthritis pain.

Sequential induction of auxin efflux and influx carriers regulates lateral root emergence (2013)
Journal Article
Peret, B., Middleton, A. M., French, A. P., Larrieu, A., Bishopp, A., Njo, M., …Bennett, M. J. (2013). Sequential induction of auxin efflux and influx carriers regulates lateral root emergence. Molecular Systems Biology, 9(1), Article 699. https://doi.org/10.1038/msb.2013.43

In Arabidopsis, lateral roots originate from pericycle cells deep within the primary root. New lateral root primordia (LRP) have to emerge through several overlaying tissues. Here, we report that auxin produced in new LRP is transported towards the o... Read More about Sequential induction of auxin efflux and influx carriers regulates lateral root emergence.

Mutations in genes involved in oestrous cycle associated expression of oestrus (2013)
Journal Article
Homer, E., Derecka, K., Webb, R., & Garnsworthy, P. (2013). Mutations in genes involved in oestrous cycle associated expression of oestrus. Animal Reproduction Science, 142(3-4), 106-112. https://doi.org/10.1016/j.anireprosci.2013.09.018

Detection of oestrus is a key determinant of profitability of dairy herds, but oestrus is increasingly difficult to observe in the modern dairy cow, with shorter duration and less intense oestrus. Concurrent with the unfavourable correlation between... Read More about Mutations in genes involved in oestrous cycle associated expression of oestrus.

MultiSig: a new high-precision approach to the analysis of complex biomolecular systems (2013)
Journal Article
Gillis, R. B., Adams, G. G., Heinze, T., Nikolajski, M., Harding, S. E., & Rowe, A. J. (2013). MultiSig: a new high-precision approach to the analysis of complex biomolecular systems. European Biophysics Journal, 42(10), https://doi.org/10.1007/s00249-013-0924-y

MultiSig is a newly developed mode of analysis of sedimentation equilibrium (SE) experiments in the analytical ultracentrifuge, having the capability of taking advantage of the remarkable precision (~0.1 % of signal) of the principal optical (fringe)... Read More about MultiSig: a new high-precision approach to the analysis of complex biomolecular systems.

Consequences of resource competition for sex allocation and discriminative behaviors in a hyperparasitoid wasp (2013)
Journal Article
Visser, B., Le Lann, C., Snaas, H., Hardy, I. C., & Harvey, J. A. (2014). Consequences of resource competition for sex allocation and discriminative behaviors in a hyperparasitoid wasp. Behavioral Ecology and Sociobiology, 68(1), 105-113. https://doi.org/10.1007/s00265-013-1627-1

Population-wide mating patterns can select for equal parental investment in both sexes, but limiting resources, such as mates or developmental substrates, can increase competition leading to biased sex ratios in favor of either sex. Such competition... Read More about Consequences of resource competition for sex allocation and discriminative behaviors in a hyperparasitoid wasp.

Meristematic cell proliferation and ribosome biogenesis are decoupled in diamagnetically levitated Arabidopsis seedlings (2013)
Journal Article
Manzano, A. I., Larkin, O. J., Dijkstra, C. E., Anthony, P., Davey, M. R., Eaves, L., …Medina, F. J. (2013). Meristematic cell proliferation and ribosome biogenesis are decoupled in diamagnetically levitated Arabidopsis seedlings. BMC Plant Biology, 13, Article 124. https://doi.org/10.1186/1471-2229-13-124

Background: Cell growth and cell proliferation are intimately linked in the presence of Earth’s gravity, but are decoupled under the microgravity conditions present in orbiting spacecraft. New technologies to simulate microgravity conditions for long... Read More about Meristematic cell proliferation and ribosome biogenesis are decoupled in diamagnetically levitated Arabidopsis seedlings.

Transmission Frequencies of Introgressed Festuca pratensis Chromosomes and Chromosome Segments in Lolium perenne (2013)
Journal Article
King, J., Armstead, I., Harper, J., & King, I. (2013). Transmission Frequencies of Introgressed Festuca pratensis Chromosomes and Chromosome Segments in Lolium perenne. Crop Science, 53(5), 1968-1973. doi:10.2135/cropsci2013.03.0209

The introgression of genetic variation from related species into crops provides an important route by which superior plant varieties can be produced. The primary aim of introgression involves the transfer of a small chromosome segment from a related... Read More about Transmission Frequencies of Introgressed Festuca pratensis Chromosomes and Chromosome Segments in Lolium perenne.

Subjective and objective components of resource value additively increase aggression in parasitoid contests (2013)
Journal Article
Stockermans, B. . C., & Hardy, I. C. W. (2013). Subjective and objective components of resource value additively increase aggression in parasitoid contests. Biology Letters, 9(4), 20130391-20130391. https://doi.org/10.1098/rsbl.2013.0391

Two major categories of factors are predicted to influence behaviour in dyadic contests; differences in the abilities of the contestants to acquire and retain resources (resource holding potential), and the value of the contested resource (resource v... Read More about Subjective and objective components of resource value additively increase aggression in parasitoid contests.

Inclusion of detergent in a cleaning regime and effect on microbial load in livestock housing (2013)
Journal Article
Hancox, L., Le Bon, M., Dodd, C. E., & Mellits, K. (2013). Inclusion of detergent in a cleaning regime and effect on microbial load in livestock housing. Veterinary Record, 173(7), https://doi.org/10.1136/vr.101392

Determining effective cleaning and disinfection regimes of livestock housing is vital to improving the health of resident animals and reducing zoonotic disease. A cleaning regime consisting of scraping, soaking with or without detergent (treatment an... Read More about Inclusion of detergent in a cleaning regime and effect on microbial load in livestock housing.

Predicting Gene Function from Uncontrolled Expression Variation among Individual Wild-Type Arabidopsis Plants (2013)
Journal Article
Bhosale, R., Jewell, J. B., Hollunder, J., Koo, A. J., Vuylsteke, M., Michoel, T., …Maere, S. (2013). Predicting Gene Function from Uncontrolled Expression Variation among Individual Wild-Type Arabidopsis Plants. Plant Cell, 25(8), 2865-2877. https://doi.org/10.1105/tpc.113.112268

Gene expression profiling studies are usually performed on pooled samples grown under tightly controlled experimental conditions to suppress variability among individuals and increase experimental reproducibility. In addition, to mask unwanted residu... Read More about Predicting Gene Function from Uncontrolled Expression Variation among Individual Wild-Type Arabidopsis Plants.