Kinetics and mechanism of G protein-coupled receptor activation
(2013)
Journal Article
Lohse, M. J., Maiellaro, I., & Calebiro, D. (2014). Kinetics and mechanism of G protein-coupled receptor activation. Current Opinion in Cell Biology, 27, 87-93. https://doi.org/10.1016/j.ceb.2013.11.009
The activation of a G protein-coupled receptor is generally triggered by binding of an agonist to the receptor's binding pocket, or, in the case of rhodopsin, by light-induced changes of the pre-bound retinal. This is followed by a series of a confor... Read More about Kinetics and mechanism of G protein-coupled receptor activation.