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Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy. (2013)
Journal Article
Ghita, A., Pascut, F. C., Sottile, V., & Notingher, I. (2013). Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy. Analyst, 139(1), https://doi.org/10.1039/C3AN01716H

Raman microscopy was used as a label-free method to study the mineralisation of bone nodules formed by mesenchymal stem cells cultured in osteogenic medium in vitro. Monitoring individual bone nodules over 28 days revealed temporal and spatial change... Read More about Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy..

Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy (2013)
Journal Article
Kong, K., Rowlands, C. J., Varma, S., Perkins, W., Leach, I. H., Koloydenko, A. A., …Notingher, I. (2013). Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy. Proceedings of the National Academy of Sciences, 110(38), https://doi.org/10.1073/pnas.1311289110

Tissue-conserving surgery is used increasingly in cancer treatment. However, one of the main challenges in this type of surgery is the detection of tumor margins. Histopathology based on tissue sectioning and staining has been the gold standard for c... Read More about Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy.