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All Outputs (11)

Returning to work after stroke: perspectives of employer stakeholders, a qualitative study. (2012)
Journal Article
Coole, C., Radford, K., Grant, M., & Terry, J. Returning to work after stroke: perspectives of employer stakeholders, a qualitative study. Journal of Occupational Rehabilitation, 23(3), https://doi.org/10.1007/s10926-012-9401-1

Purpose: More than 40 % of working age adults with stroke fail to return to work. The work context is a key factor in return to work, but little is known about the experiences of employers in supporting employees with stroke. The aim of this study wa... Read More about Returning to work after stroke: perspectives of employer stakeholders, a qualitative study..

Transient serum exposure regimes to support dual differentiation of human mesenchymal stem cells (2012)
Journal Article
France, L., Scotchford, C., Grant, D., Rashidi, H., Popov, A., & Sottile, V. (2014). Transient serum exposure regimes to support dual differentiation of human mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine, 8(8), https://doi.org/10.1002/term.1567

Human mesenchymal stem cells (MSCs), which can generate both osteoblasts and chondrocytes, represent an ideal resource for orthopaedic repair using tissue-engineering approaches. One major difficulty for the development of osteochondral constructs us... Read More about Transient serum exposure regimes to support dual differentiation of human mesenchymal stem cells.

5-Carboxylcytosine is localized to euchromatic regions in the nuclei of follicular cells in axolotl ovary (2012)
Journal Article
Alioui, A., Wheldon, L. M., Abakir, A., Ferjentsik, Z., Johnson, A. D., & Ruzov, A. (2012). 5-Carboxylcytosine is localized to euchromatic regions in the nuclei of follicular cells in axolotl ovary. Nucleus, 3(6), https://doi.org/10.4161/nucl.22799

5-Methylcytosine (5-mC) is an epigenetic modification associated with gene repression. Recent studies demonstrated that 5-mC can be enzymatically oxidised into 5-hydroxymethylcytosine and further into 5-formylcytosine (5-fC) and 5-carboxylcytsine (5-... Read More about 5-Carboxylcytosine is localized to euchromatic regions in the nuclei of follicular cells in axolotl ovary.

What determines patient preferences for treating low risk basal cell carcinoma when comparing surgery vs imiquimod?: a discrete choice experiment survey from the SINS trial (2012)
Journal Article
Tinelli, M., Ozolins, M., Bath-Hextall, F., & Williams, H. C. (2012). What determines patient preferences for treating low risk basal cell carcinoma when comparing surgery vs imiquimod?: a discrete choice experiment survey from the SINS trial. BMC Dermatology, 12(Octobe), Article 11. https://doi.org/10.1186/1471-5945-12-19

Background: The SINS trial (Controlled Clinical Trials ISRCTN48755084; Eudract No. 2004-004506-24) is a randomised controlled trial evaluating long term success of excisional surgery vs. imiquimod 5% cream for low risk nodular and superficial basal... Read More about What determines patient preferences for treating low risk basal cell carcinoma when comparing surgery vs imiquimod?: a discrete choice experiment survey from the SINS trial.

A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion (2012)
Journal Article
Guttery, D. S., Poulin, B., Ferguson, D. J. P., Szöőr, B., Wickstead, B., Carroll, P. L., …Tewari, R. (2012). A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion. PLoS Pathogens, 8(9), Article e1002948. https://doi.org/10.1371/journal.ppat.1002948

Protein phosphorylation and dephosphorylation (catalysed by kinases and phosphatases, respectively) are post-translational modifications that play key roles in many eukaryotic signalling pathways, and are often deregulated in a number of pathological... Read More about A unique protein phosphatase with kelch-like domains (PPKL) in plasmodium modulates ookinete differentiation, motility and invasion.

Thin slice sampling of video footage for mother/child interaction: application to single cases (2012)
Journal Article
James, D. M., Wadnerkar, M. B., Lam-Cassettari, C., Kang, S., & Telling, A. L. (2012). Thin slice sampling of video footage for mother/child interaction: application to single cases. Journal of Psychopathology and Behavioral Assessment, 34(3), https://doi.org/10.1007/s10862-012-9282-9

The purpose was to test the reliability of short samples of parent/child interaction for use in single-subject research. Four variable pairs of mother/child behaviour were coded for seven mother/child play sessions. Each session lasted 20 min and 18... Read More about Thin slice sampling of video footage for mother/child interaction: application to single cases.

5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development (2012)
Journal Article
Almeida, R. D., Loose, M., Sottile, V., Matsa, E., Denning, C., Young, L., …Ruzov, A. (2012). 5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development. Epigenetics, 7(4), https://doi.org/10.4161/epi.19375

5-hydroxymethyl-cytosine (5-hmc) is a cytosine modification that is relatively abundant in mammalian pre-implantation embryos and embryonic stem cells (Esc) derived from mammalian blastocysts. Recent observations imply that both 5-hmc and Tet1/2/... Read More about 5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.

Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health (2012)
Journal Article
Mobasheri, A., Henrotin, Y., Biesalski, H., & Shakibaei, M. (2012). Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health. International Journal of Molecular Sciences, 13(4), https://doi.org/10.3390/ijms13044202

Interleukin 1? (IL-1?) and tumor necrosis factor ? (TNF-?) are key cytokines that drive the production of inflammatory mediators and matrix-degrading enzymes in osteoarthritis (OA). These proinflammatory cytokines bind to their respective cell surfac... Read More about Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health.

A systematic review of studies measuring and reporting hearing aid usage in older adults since 1999: a descriptive summary of measurement tools (2012)
Journal Article
Perez, E., & Edmonds, B. A. (2012). A systematic review of studies measuring and reporting hearing aid usage in older adults since 1999: a descriptive summary of measurement tools. PLoS ONE, 7(3), Article e31831. https://doi.org/10.1371/journal.pone.0031831

Objective: A systematic review was conducted to identify and quality assess how studies published since 1999 have measured and reported the usage of hearing aids in older adults. The relationship between usage and other dimensions of hearing aid out... Read More about A systematic review of studies measuring and reporting hearing aid usage in older adults since 1999: a descriptive summary of measurement tools.

Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual worms (2012)
Journal Article
Tan, T. C., Rahman, R., Jaber-Hijazi, F., Felix, D. A., Chen, C., Louis, E. J., & Aboobaker, A. (2012). Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual worms. Proceedings of the National Academy of Sciences, 109(11), https://doi.org/10.1073/pnas.1118885109

In most sexually reproducing animals, replication and maintenance of telomeres occurs in the germ line and during early development in embryogenesis through the use of telomerase. Somatic cells generally do not maintain telomere sequences, and these... Read More about Telomere maintenance and telomerase activity are differentially regulated in asexual and sexual worms.

Additional interventions to enhance the effectiveness of individual placement and support: a rapid evidence assessment (2012)
Journal Article
Boycott, N., Schneider, J. M., & McMurran, M. (2012). Additional interventions to enhance the effectiveness of individual placement and support: a rapid evidence assessment. Rehabilitation Research and Practice, 2012(382420), https://doi.org/10.1155/2012/382420

Topic: Additional interventions used to enhance the e?ectiveness of individual placement and support (IPS). Aim: To establish whether additional interventions improve the vocational outcomes of IPS alone for people with severe mental illness. Method:... Read More about Additional interventions to enhance the effectiveness of individual placement and support: a rapid evidence assessment.