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Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition (2012)
Journal Article
Smith, S. J., Wilson, M., Ward, J. H., Rahman, C. V., Peet, A. C., Macarthur, D. C., …Rahman, R. (2012). Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition. PLoS ONE, 7(12), Article e52335. https://doi.org/10.1371/journal.pone.0052335

INTRODUCTION Physiologically relevant pre-clinical ex vivo models recapitulating CNS tumor micro-environmental complexity will aid development of biologically-targeted agents. We present comprehensive characterization of tumor aggregates generated... Read More about Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition.

Macroscopic and microscopic study of 1-Ethyl-3-methyl-imidazolium acetate-water mixtures (2012)
Journal Article
Hall, C. A., Le, K. A., Rudaz, C., Radhi, A., Lovell, C. S., Damion, R. A., …Ries, M. E. (2012). Macroscopic and microscopic study of 1-Ethyl-3-methyl-imidazolium acetate-water mixtures. Journal of Physical Chemistry B, 116(42), 12810-12818. https://doi.org/10.1021/jp306829c

Mixtures of 1-ethyl-3-methyl-imidazolium acetate ([C2mim][OAc]) and water across the entire composition range, from pure [C2mim][OAc] to pure water, have been investigated using density, viscosity, and NMR spectroscopy, relaxometry, and diffusion mea... Read More about Macroscopic and microscopic study of 1-Ethyl-3-methyl-imidazolium acetate-water mixtures.

Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties (2012)
Journal Article
Henshaw, H., Clark, D. P., Kang, S., & Ferguson, M. A. (2012). Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties. JMIR, 14(4), Article e113. https://doi.org/10.2196/jmir.2036

BACKGROUND The use of personal computers (PCs) and the Internet to provide health care information and interventions has increased substantially over the past decade. Yet the effectiveness of such an approach is highly dependent upon whether the t... Read More about Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties.

Effects of frequency discrimination training on tinnitus: results from two randomised controlled trials (2012)
Journal Article
Hoare, D. J., Kowalkowski, V. L., & Hall, D. A. (2012). Effects of frequency discrimination training on tinnitus: results from two randomised controlled trials. Journal of the Association for Research in Otolaryngology, 13(4), https://doi.org/10.1007/s10162-012-0323-6

That auditory perceptual training may alleviate tinnitus draws on two observations: (1) tinnitus probably arises from altered activity within the central auditory system following hearing loss and (2) sound-based training can change central auditory... Read More about Effects of frequency discrimination training on tinnitus: results from two randomised controlled trials.

Human cortical connectome reconstruction from diffusion weighted MRI: The effect of tractography algorithm (2012)
Journal Article
Bastiani, M., Shah, N. J., Goebel, R., & Roebroeck, A. (2012). Human cortical connectome reconstruction from diffusion weighted MRI: The effect of tractography algorithm. NeuroImage, 62(3), 1732-1749. https://doi.org/10.1016/j.neuroimage.2012.06.002

Reconstructing the macroscopic human cortical connectome by Diffusion Weighted Imaging (DWI) is a challenging research topic that has recently gained a lot of attention. In the present work, we investigate the effects of intra-voxel fiber direction m... Read More about Human cortical connectome reconstruction from diffusion weighted MRI: The effect of tractography algorithm.

Paramagnetic 19F Chemical Shift Probes that Respond Selectively to Calcium or Citrate Levels and Signal Ester Hydrolysis (2012)
Journal Article
Harvey, P., Chalmers, K. H., De?Luca, E., Mishra, A., & Parker, D. (2012). Paramagnetic 19F Chemical Shift Probes that Respond Selectively to Calcium or Citrate Levels and Signal Ester Hydrolysis. Chemistry - A European Journal, 18(28), 8748-8757. https://doi.org/10.1002/chem.201200737

Paramagnetic magnetic resonance chemical shift probes containing a proximal CF3 group have been characterised. Different systems have been created that report reversible changes in calcium ion concentrations in the millimolar regime, signal the prese... Read More about Paramagnetic 19F Chemical Shift Probes that Respond Selectively to Calcium or Citrate Levels and Signal Ester Hydrolysis.

Re-examining the evidence for a pitch-sensitive region: a human fMRI study using iterated ripple noise (2012)
Journal Article
Barker, D., Plack, C. J., & Hall, D. A. (2012). Re-examining the evidence for a pitch-sensitive region: a human fMRI study using iterated ripple noise. Cerebral Cortex, 22(4), https://doi.org/10.1093/cercor/bhr065

Human neuroimaging studies have identified a region of auditory cortex, lateral Heschl’s gyrus (HG), that shows a greater response to iterated ripple noise (IRN) than to a Gaussian noise control. Based in part on results using IRN as a pitch-evoking... Read More about Re-examining the evidence for a pitch-sensitive region: a human fMRI study using iterated ripple noise.

Spin-lattice relaxation rates and water content of freeze-dried articular cartilage (2012)
Journal Article
Damion, R. A., Pawaskar, S. S., Ries, M. E., Ingham, E., Williams, S., Jin, Z., & Radjenovic, A. (2012). Spin-lattice relaxation rates and water content of freeze-dried articular cartilage. Osteoarthritis and Cartilage, 20(2), 184-190. https://doi.org/10.1016/j.joca.2011.12.005

Objective: Nuclear magnetic resonance (NMR) spin-lattice relaxation rates were measured in bovine and porcine articular cartilage as a function of water content. Methods: Water content was varied by freeze-drying samples for short periods of time (up... Read More about Spin-lattice relaxation rates and water content of freeze-dried articular cartilage.