Effects of ?-synuclein overexpression in transgenic Caenorhabditis elegans strains
(2012)
Journal Article
Bodhicharla, R., Nagarajan, A., Winter, J., Adenle, A., Nazir, A., Brady, D., …de Pomerai, D. I. (2012). Effects of α-synuclein overexpression in transgenic Caenorhabditis elegans strains. CNS and Neurological Disorders - Drug Targets, 11(8), https://doi.org/10.2174/1871527311211080005
The neural protein α-synuclein aggregates both in vivo and in vitro to form insoluble fibrils that are involved in Parkinson’s disease pathogenesis. We have generated α-synuclein/fluorescent-protein fusion constructs overexpressed in muscle cells of... Read More about Effects of ?-synuclein overexpression in transgenic Caenorhabditis elegans strains.