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SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFN? (2011)
Journal Article
Begitt, A., Droescher, M., Knobeloch, K., & Vinkemeier, U. (2011). SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFN?. Blood, 118(4), https://doi.org/10.1182/blood-2011-04-347930

The biologic effects of IFNγ are mediated by the transcription factor STAT1. The activity of STAT1 is inhibited by small ubiquitin-like modifier (SUMO) conjugation. This occurs both directly through decreasing STAT1 tyrosine phosphorylation and indir... Read More about SUMO conjugation of STAT1 protects cells from hyperresponsiveness to IFN?.

STAT1 signaling is not regulated by a phosphorylation-acetylation switch (2011)
Journal Article
Antunes, F., Marg, A., & Vinkemeier, U. (2011). STAT1 signaling is not regulated by a phosphorylation-acetylation switch. Molecular and Cellular Biology, 31(14), https://doi.org/10.1128/MCB.05300-11

The treatment of cells with histone deacetylase inhibitors (HDACi) was reported to reveal the acetylation of STAT1 at lysine 410 and lysine 413 (O. H. Kra¨mer et al., Genes Dev. 20:473–485, 2006). STAT1 acetylation was proposed to regulate apoptosi... Read More about STAT1 signaling is not regulated by a phosphorylation-acetylation switch.