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All Outputs (346)

An ERP analysis of recognition and categorization decisions in a prototype-distortion task (2010)
Journal Article
Tunney, R. J., Fernie, G., & Astle, D. E. (2010). An ERP analysis of recognition and categorization decisions in a prototype-distortion task. PLoS ONE, 5(4), Article e10116. https://doi.org/10.1371/journal.pone.0010116

Background Theories of categorization make different predictions about the underlying processes used to represent categories. Episodic theories suggest that categories are represented in memory by storing previously encountered exemplars in memory... Read More about An ERP analysis of recognition and categorization decisions in a prototype-distortion task.

From poster to PhD: The evolution of a literature review (2010)
Book Chapter
Dixon, K., & Janks, H. (2010). From poster to PhD: The evolution of a literature review. In M. Walker, & P. Thomson (Eds.), The Routledge Doctoral Supervisor's Companion: Supporting Effective Research in Education and the Social Sciences. Routledge

A literature review evolves. At first the literature constitutes the research, then it is constituted by it. The story of the evolution of the literature review for Kerryn’s research is intertwined with the story of her evolving relationship with Hila... Read More about From poster to PhD: The evolution of a literature review.

Patterns of commissioning, contracting and care management in social care services for older people in England (2010)
Journal Article
Chester, H., Hughes, J., & Challis, D. (2010). Patterns of commissioning, contracting and care management in social care services for older people in England. British Journal of Social Work, 40(8), 2523-2537. https://doi.org/10.1093/bjsw/bcq044

A current objective of social care policy in England is to provide more personalised care services. This has implications for the provision of community based care for frail older people. Using data from a national postal survey of local authorities... Read More about Patterns of commissioning, contracting and care management in social care services for older people in England.

PRH/Hex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling (2010)
Journal Article
Noy, P., Williams, H., Sawasdichai, A., Gaston, K., & Jayaraman, P. (2010). PRH/Hex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling. Molecular and Cellular Biology, 30(9), 2120-2134. doi:10.1128/MCB.01511-09

The proline-rich homeodomain protein (PRH) plays multiple roles in the control of gene expression during embryonic development and in the adult. Vascular endothelial growth factor (VEGF) is a mitogen that stimulates cell proliferation and survival vi... Read More about PRH/Hex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling.

RepD-mediated recruitment of PcrA helicase at the Staphylococcus aureus pC221 plasmid replication origin, oriD (2010)
Journal Article
Mach?n, C., Thomson, N., Lynch, G., Scott, D. J., Thomas, C., & Soultanas, P. (2010). RepD-mediated recruitment of PcrA helicase at the Staphylococcus aureus pC221 plasmid replication origin, oriD. Nucleic Acids Research, 38(6), https://doi.org/10.1093/nar/gkp1153

Plasmid encoded replication initiation (Rep) proteins recruit host helicases to plasmid replication origins. Previously, we showed that RepD recruits directionally the PcrA helicase to the pC221 oriD, remains associated with it, and increases its pro... Read More about RepD-mediated recruitment of PcrA helicase at the Staphylococcus aureus pC221 plasmid replication origin, oriD.

Short-days induce weight loss in siberian hamsters despite overexpression of the agouti-related peptide gene (2010)
Journal Article
Jethwa, P. H., Warner, A., Fowler, M. J., Murphy, M., de Backer, M. W., Adan, R. A., …Ebling, F. J. (2010). Short-days induce weight loss in siberian hamsters despite overexpression of the agouti-related peptide gene. Journal of Neuroendocrinology, 22(6), 564-575. https://doi.org/10.1111/j.1365-2826.2010.02001.x

Many vertebrates express profound annual cycles of body fattening, although it is not clear whether these represent differential activity of the central pathways known to mediate homeostatic control of food intake and energy expenditure, or whether t... Read More about Short-days induce weight loss in siberian hamsters despite overexpression of the agouti-related peptide gene.

Haptic negotiation and role exchange for collaboration in virtual environments (2010)
Conference Proceeding
Oguz, S. O., Kucukyilmaz, A., Sezgin, T. M., & Basdogan, C. (2010). Haptic negotiation and role exchange for collaboration in virtual environments. https://doi.org/10.1109/haptic.2010.5444628

We investigate how collaborative guidance can be realized in multi-modal virtual environments for dynamic tasks involving motor control. Haptic guidance in our context can be defined as any form of force/tactile feedback that the computer generates t... Read More about Haptic negotiation and role exchange for collaboration in virtual environments.

Living with HIV/AIDS and use of online support groups (2010)
Journal Article
Mo, P. K., & Coulson, N. S. (2010). Living with HIV/AIDS and use of online support groups. Journal of Health Psychology, 15(3), 339-350. https://doi.org/10.1177/1359105309348808

The present study explores the association between online support group use and health status, coping and social support among 640 individuals with HIV/AIDS. Results suggested that frequent users tended to be female, younger, single, and in a more ad... Read More about Living with HIV/AIDS and use of online support groups.

Stochastic and deterministic multiscale models for systems biology: An auxin-transport case study (2010)
Journal Article
Twycross, J., Band, L. R., Bennett, M. J., King, J. R., & Krasnogor, N. (2010). Stochastic and deterministic multiscale models for systems biology: An auxin-transport case study. BMC Systems Biology, 4, https://doi.org/10.1186/1752-0509-4-34

Background: Stochastic and asymptotic methods are powerful tools in developing multiscale systems biology models; however, little has been done in this context to compare the efficacy of these methods. The majority of current systems biology modellin... Read More about Stochastic and deterministic multiscale models for systems biology: An auxin-transport case study.

Hybrid ortho/allosteric ligands for the adenosine A(1) receptor (2010)
Journal Article
Narlawar, R., Lane, J. R., Doddareddy, M., Lin, J., Brussee, J., & Ijzerman, A. P. (2010). Hybrid ortho/allosteric ligands for the adenosine A(1) receptor. Journal of Medicinal Chemistry, 53(8), 3028-3037. https://doi.org/10.1021/jm901252a

Many G protein-coupled receptors (GPCRs), including the adenosine A(1) receptor (A(1)AR), have been shown to be allosterically modulated by small molecule ligands. So far, in the absence of structural information, the exact location of the allosteric... Read More about Hybrid ortho/allosteric ligands for the adenosine A(1) receptor.

Targeting, care management and preventative services for older people: The cost-effectiveness of a pilot self-assessment approach in one local authority (2010)
Journal Article
Clarkson, P., Hughes, J., Challis, D., Thorley, L., & Kilshaw, C. (2010). Targeting, care management and preventative services for older people: The cost-effectiveness of a pilot self-assessment approach in one local authority. British Journal of Social Work, 40(7), 2255-2273. https://doi.org/10.1093/bjsw/bcq042

As social services councils face a more constrained economic environment and as eligibility criteria tighten, the issue of targeting becomes increasingly relevant. This paper presents findings from a pilot project in one local authority that aimed to... Read More about Targeting, care management and preventative services for older people: The cost-effectiveness of a pilot self-assessment approach in one local authority.

TopoGSA: network topological gene set analysis (2010)
Journal Article
Glaab, E., Baudot, A., Krasnogor, N., & Valencia, A. (2010). TopoGSA: network topological gene set analysis. Bioinformatics, 26(9), https://doi.org/10.1093/bioinformatics/btq131

TopoGSA (Topology-based Gene Set Analysis) is a web-application dedicated to the computation and visualization of network topological properties for gene and protein sets in molecular interaction networks. Different topological characteristics, such... Read More about TopoGSA: network topological gene set analysis.

Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration (2010)
Journal Article
Rogers, N., Paine, S., Bedford, L., & Layfield, R. (2010). Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration. Neuropathology and Applied Neurobiology, 36(2), 113-124. https://doi.org/10.1111/j.1365-2990.2010.01063.x

The significance of the accumulation of ubiquitin-positive intraneuronal inclusions in the brains of those affected with different neurodegenerative diseases is currently unclear. While one interpretation is that the disease mechanism(s) involves dys... Read More about Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration.

Garlic as an inhibitor of pseudomonas aeruginosa quorum sensing in cystic fibrosis - A pilot randomized controlled trial (2010)
Journal Article
Smyth, A. R., Cifelli, P. M., Ortori, C. A., Righetti, K., Lewis, S., Erskine, P., …Knox, A. (2010). Garlic as an inhibitor of pseudomonas aeruginosa quorum sensing in cystic fibrosis - A pilot randomized controlled trial. Pediatric Pulmonology, 45(4), 356-362. https://doi.org/10.1002/ppul.21193

Pseudomonas aeruginosa forms biofilms in the cystic fibrosis lung. Quorum sensing (QS) controls biofilm maturation, immune evasion, antibiotic tolerance and virulence factor production. Garlic shows QS inhibitory activity in vitro and in animal model... Read More about Garlic as an inhibitor of pseudomonas aeruginosa quorum sensing in cystic fibrosis - A pilot randomized controlled trial.

Differential expression and distribution of placental glutathione peroxidases 1, 3 and 4 in normal and preeclamptic pregnancy (2010)
Journal Article
Mistry, H., Kurlak, L., Williams, P., Ramsay, M., Symonds, M., & Broughton Pipkin, F. (2010). Differential expression and distribution of placental glutathione peroxidases 1, 3 and 4 in normal and preeclamptic pregnancy. Placenta, 31(5), https://doi.org/10.1016/j.placenta.2010.02.011

Preeclampsia is a pregnancy-specific condition affecting 2-7% of women and a leading cause of perinatal and maternal morbidity and mortality; it may also predispose the mother and fetus to increased risks of adult cardiovascular disease. The selenopr... Read More about Differential expression and distribution of placental glutathione peroxidases 1, 3 and 4 in normal and preeclamptic pregnancy.

'They all supported me but I felt like I suddenly didn't belong anymore': An exploration of perceived disadvantages to online support seeking (2010)
Journal Article
Malik, S., & Coulson, N. S. (2010). 'They all supported me but I felt like I suddenly didn't belong anymore': An exploration of perceived disadvantages to online support seeking. Journal of Psychosomatic Obstetrics and Gynecology, 31(3), 140-149. https://doi.org/10.3109/0167482X.2010.504870

In recent years, there has been a significant rise in the number of online support communities dedicated to issues surrounding infertility. The aim of this study was to focus on investigating the perceived disadvantages of online infertility support... Read More about 'They all supported me but I felt like I suddenly didn't belong anymore': An exploration of perceived disadvantages to online support seeking.

Case management for long-term conditions: Developing targeting processes (2010)
Journal Article
Abell, J., Hughes, J., Reilly, S., Berzins, K., & Challis, D. (2010). Case management for long-term conditions: Developing targeting processes. Care Management Journals, 11(1), 11-18. https://doi.org/10.1891/1521-0987.11.1.11

Intensive case management (ICM) is traditionally targeted atpatients with complex needs and exists within a wider service context. Targeting is integral to the efficiency of the service. A process and outcome evaluation of case management wasconducte... Read More about Case management for long-term conditions: Developing targeting processes.