LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing

James, Victoria; Zhang, Yining; Foxler, Daniel E.; de Moor, Cornelia H.; Kong, Yi Wen; Webb, Thomas M.; Self, Tim J.; Feng, Yungfeng; Lagos, Dimitrios; Chu, Chia-Ying; Rana, Tariq M.; Morley, Simon J.; Longmore, Gregory D.; Bushell, Martin; Sharp, Tyson V.

doi:10.1073/pnas.0914987107

All Outputs (3)

Maximising graduate status in pre-registration nursing programmes: Utilising problem based learning (2010)
Journal Article
McGarry, J., Aubeeluck, A., James, V., & Hinsliff-Smith, K. (2011). Maximising graduate status in pre-registration nursing programmes: Utilising problem based learning. Nurse Education in Practice, 11(6), 342-344. doi:10.1016/j.nepr.2010.11.018

This paper debates the use of problem based learning in accelerated pre-registration nursing programmes that are specifically designed for candidates with ‘graduate status’. We discuss the benefits of using problem based learning (PBL) within a gradu... Read More about Maximising graduate status in pre-registration nursing programmes: Utilising problem based learning.

Knockdown of microRNA-21 Inhibits Proliferation and Increases Cell Death by Targeting Programmed Cell Death 4 (PDCD4) in Pancreatic Ductal Adenocarcinoma (2010)
Journal Article
Bhatti, I., Lee, A., James, V., Hall, R. I., Lund, J. N., Tufarelli, C., …Larvin, M. (2011). Knockdown of microRNA-21 Inhibits Proliferation and Increases Cell Death by Targeting Programmed Cell Death 4 (PDCD4) in Pancreatic Ductal Adenocarcinoma. Journal of Gastrointestinal Surgery, 15(1), 199-208. https://doi.org/10.1007/s11605-010-1381-x

LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing (2010)
Journal Article
James, V., Zhang, Y., Foxler, D. E., de Moor, C. H., Kong, Y. W., Webb, T. M., …Sharp, T. V. (2010). LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing. Proceedings of the National Academy of Sciences, 107(28), 12499-12504. https://doi.org/10.1073/pnas.0914987107

In recent years there have been major advances with respect to the identification of the protein components and mechanisms of microRNA (miRNA) mediated silencing. However, the complete and precise repertoire of components and mechanism(s) of action r... Read More about LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.