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All Outputs (8)

Identification of sortase A (SrtA) substrates in Streptococcus uberis: evidence for an additional hexapeptide (LPXXXD) sorting motif (2009)
Journal Article
Egan, S. A., Kurian, D., Ward, P. N., Hunt, L., & Leigh, J. A. (2009). Identification of sortase A (SrtA) substrates in Streptococcus uberis: evidence for an additional hexapeptide (LPXXXD) sorting motif. Journal of Proteome Research, 9(2), https://doi.org/10.1021/pr901025w

Sortase (a transamidase) has been shown to be responsible for the covalent attachment of proteins to the bacterial cell wall. Anchoring is effected on secreted proteins containing a specific cell wall motif toward their C-terminus; that for sortase A... Read More about Identification of sortase A (SrtA) substrates in Streptococcus uberis: evidence for an additional hexapeptide (LPXXXD) sorting motif.

Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis (2009)
Journal Article
Rutland, C., Warner, L., Thorpe, A., Alibhai, A., Robinson, T., Shaw, B., …Loughna, S. (2009). Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis. Journal of Anatomy, 214(6), 905-915. https://doi.org/10.1111/j.1469-7580.2009.01079.x

Atrial septal defects are a common congenital heart defect in humans. Although mutations in different genes are now frequently being described, little is known about the processes and mechanisms behind the early stages of atrial septal development. B... Read More about Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis.

Management interventions in dairy herds: exploring within herd uncertainty using an integrated Bayesian model (2009)
Journal Article
Green, M. J., Medley, G. F., Bradley, A. J., & Browne, W. J. (2009). Management interventions in dairy herds: exploring within herd uncertainty using an integrated Bayesian model. Veterinary Research, 41(2), Article Article 22. https://doi.org/10.1051/vetres/2009070

Knowledge of the efficacy of an intervention for disease control on an individual farm is essential to make good decisions on preventive healthcare, but the uncertainty in outcome associated with undertaking a specific control strategy has rarely b... Read More about Management interventions in dairy herds: exploring within herd uncertainty using an integrated Bayesian model.

Bayesian analysis of a mastitis control plan to investigate the influence of veterinary prior beliefs on clinical interpretation (2009)
Journal Article
Green, M. J., Browne, W. J., Green, L., Bradley, A. J., Leach, K., Breen, J., & Medley, G. F. (2009). Bayesian analysis of a mastitis control plan to investigate the influence of veterinary prior beliefs on clinical interpretation. Preventive Veterinary Medicine, 91(2-4), https://doi.org/10.1016/j.prevetmed.2009.05.029

The fundamental objective for health research is to determine whether changes should be made to clinical decisions. Decisions made by veterinary surgeons in the light of new research evidence are known to be influenced by their prior beliefs, especia... Read More about Bayesian analysis of a mastitis control plan to investigate the influence of veterinary prior beliefs on clinical interpretation.

Use of posterior predictive assessments to evaluate model fit in multilevel logistic regression (2009)
Journal Article
Green, M. J., Medley, G. F., & Browne, W. J. (2009). Use of posterior predictive assessments to evaluate model fit in multilevel logistic regression. Veterinary Research, 40(4), Article Article 30. https://doi.org/10.1051/vetres/2009013

Assessing the fit of a model is an important final step in any statistical analysis, but this is not straightforward when complex discrete response models are used. Cross validation and posterior predictions have been suggested as methods to aid mode... Read More about Use of posterior predictive assessments to evaluate model fit in multilevel logistic regression.