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Quaternary climate instability as the driver of genetic diversification in Neogloboquadrina pachyderma (sin) (2006)
Journal Article
Darling, K., Kucera, M., & Wade, C. (2006). Quaternary climate instability as the driver of genetic diversification in Neogloboquadrina pachyderma (sin). 00 Journal not listed, 29(1), 533. https://doi.org/10.11137/2006_1_533-533

Molecular genetic analysis shows that many planktonic foraminiferal morphospecies represent complexes of several distinct genetic types with distinct ecologies and distributions. Such cryptic diversity is common in most planktonic protists. Global bi... Read More about Quaternary climate instability as the driver of genetic diversification in Neogloboquadrina pachyderma (sin).

Molecular and morphological studies of Streptochilus from the Arabian Sea (2006)
Journal Article
Darling, K., Thomas, E., & Wade, C. (2006). Molecular and morphological studies of Streptochilus from the Arabian Sea. 00 Journal not listed, 29(1), 187--187. https://doi.org/10.11137/2006_1_187-187

Specimens of the biserial planktonic foraminiferal genus Streptochilus were collected 540 nautical miles offshore in the central Arabian Sea during the summer monsoon of 2003. Samples were collected from 5m water depth in waters with an average depth... Read More about Molecular and morphological studies of Streptochilus from the Arabian Sea.

Temporal change in gene expression in the rat dentate gyrus following passive avoidance learning (2006)
Journal Article
O'Sullivan, N. C., McGettigan, P. A., Sheridan, G. K., Pickering, M., Conboy, L., O'Connor, J. J., …Murphy, K. J. (2007). Temporal change in gene expression in the rat dentate gyrus following passive avoidance learning. Journal of Neurochemistry, 101(4), 1085-1098. https://doi.org/10.1111/j.1471-4159.2006.04418.x

A learning event initiates a cascade of altered gene expression leading to synaptic remodelling within the hippocampal dentate gyrus, a structure vital to memory formation. To illuminate this transcriptional program of synaptic plasticity we used mic... Read More about Temporal change in gene expression in the rat dentate gyrus following passive avoidance learning.

Asthma as a barrier to children's physical activity: Implications for body mass index and mental health (2006)
Journal Article
Glazebrook, C., McPherson, A. C., Macdonald, I. A., Swift, J. A., Ramsay, C., Newbould, R., & Smyth, A. (2006). Asthma as a barrier to children's physical activity: Implications for body mass index and mental health. Pediatrics, 118(6), 2443-2449. https://doi.org/10.1542/peds.2006-1846

OBJECTIVES. The purpose of this work was to identify barriers to physical activity in children with asthma and to compare their customary activity levels, BMI and emotional well-being with that of children with other medical conditions. It was hypoth... Read More about Asthma as a barrier to children's physical activity: Implications for body mass index and mental health.

Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages (2006)
Journal Article
Rosas-Magallanes, V., Stadthagen-Gomez, G., Rauzier, J., Barreiro, L. B., Tailleux, L., Boudou, F., …Neyrolles, O. (2007). Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages. Infection and Immunity, 75(1), 504-507. https://doi.org/10.1128/IAI.00058-06

Using signature-tagged transposon mutagenesis, we isolated 23 Mycobacterium tuberculosis mutants, corresponding to 21 genes or genetic regions, attenuated in their ability to parasitize human macrophages. Mutants disrupted in the ABC transporter-enco... Read More about Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages.

T-cell stimulating protein A (TspA) of Neisseria meningitidis is required for optimal adhesion to human cells (2006)
Journal Article
Oldfield, N. J., Bland, S. J., Taraktsoglou, M., Dos Ramos, F. J., Robinson, K., Wooldridge, K. G., & Ala'Aldeen, D. A. (2007). T-cell stimulating protein A (TspA) of Neisseria meningitidis is required for optimal adhesion to human cells. Cellular Microbiology, 9(2), 463-478. https://doi.org/10.1111/j.1462-5822.2006.00803.x

T-cell stimulating protein A (TspA) is an immunogenic, T-cell and B-cell stimulating protein of Neisseria meningitidis. Sequence similarity between TspA and FimV, a Pseudomonas aeruginosa protein involved in twitching motility, suggested a link betwe... Read More about T-cell stimulating protein A (TspA) of Neisseria meningitidis is required for optimal adhesion to human cells.

Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding (2006)
Journal Article
Owsianka, A. M., Timms, J. M., Tarr, A. W., Brown, R. J., Hickling, T. P., Szwejk, A., …Ball, J. K. (2006). Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding. Journal of Virology, 80(17), 8695-8704. https://doi.org/10.1128/JVI.00271-06

Hepatitis C virus (HCV) cell entry involves interaction between the viral envelope glycoprotein E2 and the cell surface receptor CD81. Knowledge of conserved E2 determinants important for successful binding will facilitate development of entry inhibi... Read More about Identification of Conserved Residues in the E2 Envelope Glycoprotein of the Hepatitis C Virus That Are Critical for CD81 Binding.

Internally quenched peptides for the study of lysostaphin: An antimicrobial protease that kills Staphylococcus aureus (2006)
Journal Article
Warfield, R., Bardelang, P., Saunders, H., Chan, W. C., Penfold, C., James, R., & Thomas, N. R. (2006). Internally quenched peptides for the study of lysostaphin: An antimicrobial protease that kills Staphylococcus aureus. Organic and Biomolecular Chemistry, 4(19), 3626-3638. https://doi.org/10.1039/b607999g

Lysostaphin (EC. 3.4.24.75) is a protein secreted by Staphylococcus simulans biovar staphylolyticus and has been shown to be active against methicillin resistant S. aureus (MRSA). The design and synthesis of three internally quenched substrates for l... Read More about Internally quenched peptides for the study of lysostaphin: An antimicrobial protease that kills Staphylococcus aureus.

General practice characteristics associated with rates of testing and detection of hepatitis C: Cross-sectional study in Nottingham and Derbyshire (2006)
Journal Article
Coupland, C., Hippisley-Cox, J., Smith, S., Irving, W., Pringle, M., Ryder, S., …Bullock, D. (2006). General practice characteristics associated with rates of testing and detection of hepatitis C: Cross-sectional study in Nottingham and Derbyshire. British Journal of General Practice, 56(529), 620-623

The aim of this study was to determine general practice characteristics associated with testing rates for hepatitis C virus (HCV) and the proportion of tests with a positive result. The study included all patients tested for HCV from all general prac... Read More about General practice characteristics associated with rates of testing and detection of hepatitis C: Cross-sectional study in Nottingham and Derbyshire.

A resolution for the coiling direction paradox in Neogloboquadrina pachyderma (2006)
Journal Article
Darling, K. F., Kucera, M., Kroon, D., & Wade, C. M. (2006). A resolution for the coiling direction paradox in Neogloboquadrina pachyderma. Paleoceanography, 21(2), Article PA2011. https://doi.org/10.1029/2005PA001189

We present new data on genotypic differences and biogeographic distribution of coiling types in the living planktonic foraminiferal morphospecies Neogloboquadrina pachyderma. The genetic evidence demonstrates that coiling direction in N. pachyderma i... Read More about A resolution for the coiling direction paradox in Neogloboquadrina pachyderma.

In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris (2006)
Journal Article
Stepek, G., Lowe, A., Buttle, D. J., Duce, I., & Behnke, J. M. (2006). In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris. Parasitology, 132(5), https://doi.org/10.1017/S003118200500973X

Extracts of plants, such as papaya, pineapple and fig, are known to be effective at killing intestinal nematodes that inhabit anterior sites in the small intestine, such as Heligmosomoides polygyrus. In this paper, we demonstrate that similar in vitr... Read More about In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris.

Evolutionary relationships among the Pulmonate land snails and slugs (Pulmonata, Stylommatophora) (2006)
Journal Article
Wade, C. M., Mordan, P. B., & Naggs, F. (2006). Evolutionary relationships among the Pulmonate land snails and slugs (Pulmonata, Stylommatophora). Biological Journal of the Linnean Society, 87(4), 593-610. https://doi.org/10.1111/j.1095-8312.2006.00596.x

We have incorporated an additional 56 species of land snails and slugs in our ribosomal (r) RNA molecular phylogeny. The new taxa include representatives of several important groups. The molecular tree now includes 160 species of stylommatophoran lan... Read More about Evolutionary relationships among the Pulmonate land snails and slugs (Pulmonata, Stylommatophora).

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33 (2006)
Journal Article
Tarr, A. W., Owsianka, A. M., Timms, J. M., McClure, C. P., Brown, R. J., Hickling, T. P., …Ball, J. K. (2006). Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33. Hepatology, 43(3), 592-601. https://doi.org/10.1002/hep.21088

The mouse monoclonal antibody (MAb) AP33, recognizing a 12 amino acid linear epitope in the hepatitis C virus (HCV) E2 glycoprotein, potently neutralizes retroviral pseudoparticles (HCVpp) carrying genetically diverse HCV envelope glycoproteins. Cons... Read More about Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

A classification of tasks for the systematic study of immune response using functional genomics data (2006)
Journal Article
Hedeler, C., Paton, N., Behnke, J. M., Bradley, J. E., Hamshere, M., & Else, K. (2006). A classification of tasks for the systematic study of immune response using functional genomics data. Parasitology, 132(2), https://doi.org/10.1017/S0031182005008796

A full understanding of the immune system and its responses to infection by different pathogens is important for the development of anti-parasitic vaccines. A growing number of large-scale experimental techniques, such as microarrays, are being used... Read More about A classification of tasks for the systematic study of immune response using functional genomics data.

A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans (2006)
Journal Article
Dawe, A. S., Smith, B., Thomas, D. W., Greedy, S., Vasic, N., Gregory, A., …de Pomerai, D. I. (2006). A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans. Bioelectromagnetics, 27(2), https://doi.org/10.1002/bem.20192

We have previously reported that low-intensity microwave exposure (0.75-1.0 GHz CW at 0.5 W; SAR 4-40 mW kg-1) can induce an apparently non-thermal heat-shock response in Caenorhabditis elegans worms carrying hsp16-1::reporter genes. Using matched co... Read More about A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans.

The effect of the hookworm Ancylostoma ceylanicum on the mucosal architecture of the small intestine in hamsters (2006)
Journal Article
Alkazmi, L., Dehlawi, M., & Behnke, J. (2006). The effect of the hookworm Ancylostoma ceylanicum on the mucosal architecture of the small intestine in hamsters. Journal of Helminthology, 80(4), https://doi.org/10.1017/JOH2006372

Hookworms are known to cause marked changes to the intestinal mucosa, especially in relation to erosion of the villi. However, since the development of enteropathy has not been examined thoroughly through quantitative experiments on infected animals,... Read More about The effect of the hookworm Ancylostoma ceylanicum on the mucosal architecture of the small intestine in hamsters.

Molecular evidence that Heligmosomoides polygyrus from laboratory mice and wood mice are separate species (2006)
Journal Article
Cable, J., Harris, P., Lewis, J., & Behnke, J. (2006). Molecular evidence that Heligmosomoides polygyrus from laboratory mice and wood mice are separate species. Parasitology, 133(1), https://doi.org/10.1017/S0031182006000047

The gastro-intestinal (GI) nematode Heligmosomoides polygyrus is an important experimental model in laboratory mice and a well-studied parasite of wood mice in the field. Despite an extensive literature, the taxonomy of this parasite in different hos... Read More about Molecular evidence that Heligmosomoides polygyrus from laboratory mice and wood mice are separate species.

Effects of radio-frequency fields on bacterial cell membranes and nematode temperature-sensitive mutants (2006)
Journal Article
Gul Guven, R., Guven, K., Dawe, A., Worthington, J., Harvell, C., Popple, A., …de Pomerai, D. I. (2006). Effects of radio-frequency fields on bacterial cell membranes and nematode temperature-sensitive mutants. Enzyme and Microbial Technology, 39(4), https://doi.org/10.1016/j.enzmictec.2005.12.017

Membrane-related bioeffects have been reported in response to both radio-frequency (RF) and extremely low-frequency (ELF) electromagnetic fields (EMFs), particularly in neural cells. We have tested whether RF fields might cause inner membrane leakage... Read More about Effects of radio-frequency fields on bacterial cell membranes and nematode temperature-sensitive mutants.

The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection (2006)
Journal Article
Lewis, R., Behnke, J. M., Stafford, P., & Holland, C. V. (2006). The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection. Parasitology, 132(2), https://doi.org/10.1017/S0031182005008978

Ascaris suum and Ascaris lumbricoides exhibit an over-dispersed frequency distribution in their host populations in both the adult and larval stages. The impact of host factors on this observed distribution is still poorly understood and difficult to... Read More about The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection.