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In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris (2006)
Journal Article
Stepek, G., Lowe, A., Buttle, D. J., Duce, I., & Behnke, J. M. (2006). In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris. Parasitology, 132(5), doi:10.1017/S003118200500973X

Extracts of plants, such as papaya, pineapple and fig, are known to be effective at killing intestinal nematodes that inhabit anterior sites in the small intestine, such as Heligmosomoides polygyrus. In this paper, we demonstrate that similar in vitr... Read More about In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris.

A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans (2006)
Journal Article
Dawe, A. S., Smith, B., Thomas, D. W., Greedy, S., Vasic, N., Gregory, A., …de Pomerai, D. I. (2006). A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans. Bioelectromagnetics, 27(2), doi:10.1002/bem.20192

We have previously reported that low-intensity microwave exposure (0.75-1.0 GHz CW at 0.5 W; SAR 4-40 mW kg-1) can induce an apparently non-thermal heat-shock response in Caenorhabditis elegans worms carrying hsp16-1::reporter genes. Using matched co... Read More about A small temperature rise may contribute towards the apparent induction by microwaves of heatshock gene expression in the nematode Caenorhabditis elegans.

A classification of tasks for the systematic study of immune response using functional genomics data (2006)
Journal Article
Hedeler, C., Paton, N., Behnke, J. M., Bradley, J. E., Hamshere, M., & Else, K. (2006). A classification of tasks for the systematic study of immune response using functional genomics data. Parasitology, 132(2), doi:10.1017/S0031182005008796

A full understanding of the immune system and its responses to infection by different pathogens is important for the development of anti-parasitic vaccines. A growing number of large-scale experimental techniques, such as microarrays, are being used... Read More about A classification of tasks for the systematic study of immune response using functional genomics data.

The effect of the hookworm Ancylostoma ceylanicum on the mucosal architecture of the small intestine in hamsters (2006)
Journal Article
Alkazmi, L., Dehlawi, M., & Behnke, J. (2006). The effect of the hookworm Ancylostoma ceylanicum on the mucosal architecture of the small intestine in hamsters. Journal of Helminthology, 80(4), doi:10.1017/JOH2006372

Hookworms are known to cause marked changes to the intestinal mucosa, especially in relation to erosion of the villi. However, since the development of enteropathy has not been examined thoroughly through quantitative experiments on infected animals,... Read More about The effect of the hookworm Ancylostoma ceylanicum on the mucosal architecture of the small intestine in hamsters.

The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection (2006)
Journal Article
Lewis, R., Behnke, J. M., Stafford, P., & Holland, C. V. (2006). The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection. Parasitology, 132(2), doi:10.1017/S0031182005008978

Ascaris suum and Ascaris lumbricoides exhibit an over-dispersed frequency distribution in their host populations in both the adult and larval stages. The impact of host factors on this observed distribution is still poorly understood and difficult to... Read More about The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection.

Molecular evidence that Heligmosomoides polygyrus from laboratory mice and wood mice are separate species (2006)
Journal Article
Cable, J., Harris, P., Lewis, J., & Behnke, J. (2006). Molecular evidence that Heligmosomoides polygyrus from laboratory mice and wood mice are separate species. Parasitology, 133(1), doi:10.1017/S0031182006000047

The gastro-intestinal (GI) nematode Heligmosomoides polygyrus is an important experimental model in laboratory mice and a well-studied parasite of wood mice in the field. Despite an extensive literature, the taxonomy of this parasite in different hos... Read More about Molecular evidence that Heligmosomoides polygyrus from laboratory mice and wood mice are separate species.

Effects of radio-frequency fields on bacterial cell membranes and nematode temperature-sensitive mutants (2006)
Journal Article
Gul Guven, R., Guven, K., Dawe, A., Worthington, J., Harvell, C., Popple, A., …de Pomerai, D. I. (2006). Effects of radio-frequency fields on bacterial cell membranes and nematode temperature-sensitive mutants. Enzyme and Microbial Technology, 39(4), doi:10.1016/j.enzmictec.2005.12.017

Membrane-related bioeffects have been reported in response to both radio-frequency (RF) and extremely low-frequency (ELF) electromagnetic fields (EMFs), particularly in neural cells. We have tested whether RF fields might cause inner membrane leakage... Read More about Effects of radio-frequency fields on bacterial cell membranes and nematode temperature-sensitive mutants.