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Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth (2006)
Journal Article
Rahman, R., Mo, L., & Cui, W. (2006). Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth. Biochemical and Biophysical Research Communications, 350(3), 796-802. doi:10.1016/j.bbrc.2006.09.125

Telomerase catalytic subunit (TERT) seems a key factor controlling telomerase activity, telomere length, and cell growth. To further address this issue, we forced expression of a catalytically inactive mutant human TERT (hTERT) in hTERT-immortalised... Read More about Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth.