Research Repository

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Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem Cell Trial of Recovery EnhanceMent After Stroke (STEMS) Pilot Randomized, Controlled Trial (ISRCTN 16784092) (2006)
Journal Article
Sprigg, N., Bath, P. M., Zhao, L., Willmot, M., Gray, L. J., Walker, M. F., …Russell, N. (2006). Granulocyte-colony-stimulating factor mobilizes bone marrow stem cells in patients with subacute ischemic stroke: the Stem Cell Trial of Recovery EnhanceMent After Stroke (STEMS) Pilot Randomized, Controlled Trial (ISRCTN 16784092). Stroke, 37(12), 2979-2983. doi:10.1161/01.str.0000248763.49831.c3

Background and Purpose - Loss of motor function is common after stroke and leads to significant chronic disability. Stem cells are capable of self-renewal and of differentiating into multiple cell types, including neurones, glia, and vascular cells.... Read More

Fundamental behaviour of Virtual-Build-to-Order systems (2006)
Journal Article
Brabazon, P. G., & MacCarthy, B. L. (2006). Fundamental behaviour of Virtual-Build-to-Order systems. International Journal of Production Economics, 104(2),

Virtual-Build-to-Order (VBTO) is an emerging order fulfilment system within the automotive sector that is intended to improve fulfilment performance by taking advantage of integrated information systems. The primary innovation in VBTO systems is the... Read More

Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain (2006)
Journal Article
Jhaveri, M., Richardson, D., Kendall, D., Barrett, D., & Chapman, V. (2006). Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain

Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states. The aim of... Read More

A quadrivalent vaccine for human papillomavirus (2006)
Journal Article
Brown, C., & Gaston, K. (2006). A quadrivalent vaccine for human papillomavirus. Drugs of today (Barcelona, Spain : 1998), 42(11), 703-709. doi:10.1358/dot.2006.42.11.1032056

Cervical cancer is responsible for at least 13,500 deaths a year in the European Union and more than 30 times that worldwide. DNA from a group of human papillomaviruses (HPVs) is found in virtually all cervical carcinoma cells, and these so-called hi... Read More

The role of cannabinoids in the neurobiology of sensory gating: a firing rate model study (2006)
Journal Article
Zachariou, M., Dissanayake, D., Owen, M. R., Mason, R., & Coombes, S. The role of cannabinoids in the neurobiology of sensory gating: a firing rate model study. Neurocomputing, 70(10/12), doi:10.1016/j.neucom.2006.10.065

Gating of sensory (e.g. auditory) information has been demonstrated as a reduction in the auditory-evoked potential responses recorded in the brain of both normal animals and human subjects. Auditory gating is perturbed in schizophrenic patients and... Read More

Study of aero-engine oil-air separators (2006)
Journal Article
Wang, Y., Simmons, K., Eastwick, C., & Hibberd, S. (2006). Study of aero-engine oil-air separators. Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, 220(7), doi:10.1243/09576509JPE116

For aero-engines, oil-air separation is a key function, and one approach to assessing separator effectiveness is computational fluid dynamics (CFD). The two-phase flow is complex and oil can be present in different forms (for example, droplets, mist,... Read More

Persistent localized states for a chaotically mixed bistable reaction (2006)
Journal Article
Cox, S. M. (2006). Persistent localized states for a chaotically mixed bistable reaction. Physical Review E, 74(5),

We describe the evolution of a bistable chemical reaction in a closed two-dimensional chaotic laminar flow, from a localized initial disturbance. When the fluid mixing is sufficiently slow, the disturbance may spread and eventually occupy the entire... Read More

Effect of nitric oxide donors on blood pressure and pulse pressure in acute and subacute stroke (2006)
Journal Article
Gray, L. J., Sprigg, N., Rashid, P., Willmot, M., & Bath, P. M. (2006). Effect of nitric oxide donors on blood pressure and pulse pressure in acute and subacute stroke. Journal of Stroke and Cerebrovascular Diseases, 15(6),

High blood pressure (BP), pulse pressure (PP), and rate pressure product (RPP) areeach associated independently with a poor outcome in acute ischemic stroke. Whereas nitric oxide (NO) donors, such as glyceryl trinitrate (GTN), lower blood pressure i... Read More

Application of airborne LiDAR to mapping seismogenic faults in forested mountainous terrain, southeastern Alps, Slovenia (2006)
Journal Article
Cunningham, D., Grebby, S., Tansey, K., Gosar, A., & Kastelic, V. (2006). Application of airborne LiDAR to mapping seismogenic faults in forested mountainous terrain, southeastern Alps, Slovenia. Geophysical Research Letters, 30(20), doi:10.1029/2006GL027014

Results are presented of the first airborne LiDAR survey ever flown in Europe for the purpose of mapping the surface expression of earthquake-prone faults. Detailed topographic images derived from LiDAR data of the Idrija and Ravne strike-slip faults... Read More

Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages (2006)
Journal Article
Rosas-Magallanes, V., Stadthagen-Gomez, G., Rauzier, J., Barreiro, L. B., Tailleux, L., Boudou, F., …Neyrolles, O. (2007). Signature-tagged transposon mutagenesis identifies novel mycobacterium tuberculosis genes involved in the parasitism of human macrophages. Infection and Immunity, 75(1), doi:10.1128/IAI.00058-06

Using signature-tagged transposon mutagenesis, we isolated 23 Mycobacterium tuberculosis mutants, corresponding to 21 genes or genetic regions, attenuated in their ability to parasitize human macrophages. Mutants disrupted in the ABC transporter-enco... Read More

Inhibition of metal dusting using thermal spray coatings and laser treatment (2006)
Journal Article
Voisey, K., Liu, Z., & Stott, F. (2006). Inhibition of metal dusting using thermal spray coatings and laser treatment. Surface and Coatings Technology, 201(3-4), doi:10.1016/j.surfcoat.2005.12.020

Alloy 600 and Alloy 800H are susceptible to metal dusting. Both alloys were thermally sprayed with two different corrosion resistant coatings: Ni50Cr and Ni31Cr11Al0.6Y. Laser remelting was used to enhance further the effectiveness of these coatings... Read More

Morphological characteristics of the limbal epithelial crypt (2006)
Journal Article
Shanmuganathan, V. A., Foster, T., Kulkarni, B. B., Hopkinson, A., Gray, T., Powe, D. G., …Dua, H. S. (2007). Morphological characteristics of the limbal epithelial crypt. British Journal of Ophthalmology, 91(4), 514-519. doi:10.1136/bjo.2006.102640

Aim: In 2005 we reported the discovery of a novel anatomical structure at the limbus, which we termed the limbal epithelial crypt (LEC). The purpose of this study was to further evaluate the distribution, immunophenotypical, and ultra structural char... Read More

Can foster carers help children resolve their emotional and behavioural difficulties? (2006)
Journal Article
Wilson, K. (2006). Can foster carers help children resolve their emotional and behavioural difficulties?. Clinical Child Psychology and Psychiatry, 11(4), doi:10.1177/1359104506067873

Although foster care is generally seen as providing a positive experience for the children and young people for whom it caters, it is rarely conceived of as a place where the children are helped to address their emotional difficulties and modify thei... Read More

Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth (2006)
Journal Article
Rahman, R., Mo, L., & Cui, W. (2006). Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth. Biochemical and Biophysical Research Communications, 350(3), 796-802. doi:10.1016/j.bbrc.2006.09.125

Telomerase catalytic subunit (TERT) seems a key factor controlling telomerase activity, telomere length, and cell growth. To further address this issue, we forced expression of a catalytically inactive mutant human TERT (hTERT) in hTERT-immortalised... Read More

The future of tuberculosis vaccinology (2006)
Book Chapter
Griffin, R., & Young, D. (2006). The future of tuberculosis vaccinology. In M. C. Raviglione (Ed.), Reichman and Hershfield's tuberculosis : a comprehensive, international approach, 1153-1168. (3rd ed.). Informa Healthcare

Scaling in a SU(2)/Z_3 model of cosmic superstring networks (2006)
Journal Article
Hindmarsh, M., & Saffin, P. (2006). Scaling in a SU(2)/Z_3 model of cosmic superstring networks. Journal of High Energy Physics, 2006(8), doi:10.1088/1126-6708/2006/08/066

Motivated by recent developments in superstring theory in the cosmological context, we examine a field theory which contains string networks with 3-way junctions. We perform numerical simulations of this model, identify the length scales of the netwo... Read More

The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein (2006)
Journal Article
Hooley, E., Fairweather, V., Clarke, A. R., Gaston, K., & Brady, R. L. (2006). The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein. Nucleic Acids Research, 34(14), 3897-3908. doi:10.1093/nar/gkl466

The E2 proteins are transcription/replication factors from papillomaviruses. Human papillomaviruses (HPVs) can be broadly divided in two groups; low-risk HPV subtypes cause benign warts while high-risk HPVs give rise to cervical cancer. Although a ra... Read More

Volatile emission by contest losers revealed by real-time chemical analysis (2006)
Journal Article
Goubault, M., Batchelor, T. P., Linforth, R. S., Taylor, A. J., & Hardy, I. C. (2006). Volatile emission by contest losers revealed by real-time chemical analysis. Proceedings of the Royal Society B: Biological Sciences, 273(1603), 2853-2859. doi:10.1098/rspb.2006.3655

Animal interactions often involve chemical exchange but simultaneous evaluation of chemistry and behaviour has been problematical. Here we report findings from a novel method, atmospheric pressure chemical ionization-mass spectrometry (APCI-MS) coupl... Read More

The flow generated in a continuously stratified rotating fluid by the differential rotation of a plane horizontal disc (2006)
Journal Article
Munro, R. J., & Davies, P. (2006). The flow generated in a continuously stratified rotating fluid by the differential rotation of a plane horizontal disc. Fluid Dynamics Research, 38(8), doi:10.1016/j.fluiddyn.2006.03.002

Results are presented from a modelling investigation into the response of a rotating, linearly stratified fluid to local forcing induced by a differentially rotating smooth, horizontal disc. Attention was directed at cases in which the disc forcing i... Read More