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All Outputs (6)

Investigation of human T cell responses to HPV16 E2 (2000)
Conference Proceeding
Davidson, E., Brown, M., Burt, D., Mulryan, K., Clayton, A., Gaston, K., …Stern, P. (2000). Investigation of human T cell responses to HPV16 E2. In The 18th International Papillomavirus Conference

Myc and YY1 mediate activation of the Surf-1 promoter in response to serum growth factors (2000)
Journal Article
Vernon, E. G., & Gaston, K. (2000). Myc and YY1 mediate activation of the Surf-1 promoter in response to serum growth factors. BBA - Biochimica et Biophysica Acta, 1492(1), 172-179. doi:10.1016/S0167-4781(00)00116-0

The human Surf-1 and Surf-2 genes are divergently transcribed and share a single bi-directional promoter. The addition of serum growth factors to serum-starved cells activates transcription in the Surf-1 direction, but has no effect on transcription... Read More about Myc and YY1 mediate activation of the Surf-1 promoter in response to serum growth factors.

The HPV 16 E2 protein induces p53-dependent apoptosis (2000)
Presentation / Conference
Gaston, K., Webster, K., Roeder, G., & Parish, J. (2000, April). The HPV 16 E2 protein induces p53-dependent apoptosis. Paper presented at 10th TENOVUS Scotland Symposium: Gene Expression and Disease

The human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway (2000)
Journal Article
Webster, K., Parish, J., Pandya, M., Stern, P. L., Clarke, A. R., & Gaston, K. (2000). The human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway. Journal of Biological Chemistry, 275(1), 87-94. doi:10.1074/jbc.275.1.87

The human papillomavirus (HPV) E2 protein regulates viral gene expression and is also required for viral replication. HPV-transformed cells often contain chromosomally integrated copies of the HPV genome in which the viral E2 gene is disrupted. We ha... Read More about The human papillomavirus (HPV) 16 E2 protein induces apoptosis in the absence of other HPV proteins and via a p53-dependent pathway.