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All Outputs (15)

Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche (2018)
Working Paper
Prina, E., Sidney, L., Tromayer, M., Moore, J., Liska, R., Bertolin, M., …Rose, F. R. Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche

Stem cells within epithelial tissues reside in anatomical structures known as crypts that are known to contribute to the mechanical and chemical milieu important for function. To date, epithelial stem cell therapies have largely ignored the niche and... Read More about Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche.

Joining Standards Organizations: the role of R&D expenditures, patents, and the product-market position (2018)
Working Paper
Baron, J., Li, C., & Nasirov, S. (2018). Joining Standards Organizations: the role of R&D expenditures, patents, and the product-market position

This paper studies collaborative innovation in the context of developing open technology standards coordinated by standards organizations. Using longitudinal data from the world's largest R&D investors matched with membership information from 180 sta... Read More about Joining Standards Organizations: the role of R&D expenditures, patents, and the product-market position.

'Sedimented Histories' and 'Embodied Legacies': Creating an Evaluative Framework for Engaging the Public in the First World War (2018)
Working Paper
Allwork, L. 'Sedimented Histories' and 'Embodied Legacies': Creating an Evaluative Framework for Engaging the Public in the First World War

This working paper chronicles the development of the construction of a methodological framework for the evaluation of the impact of the Centre for Hidden Histories, one of the AHRC’s First World War Engagement Centres. It will show how through evalu... Read More about 'Sedimented Histories' and 'Embodied Legacies': Creating an Evaluative Framework for Engaging the Public in the First World War.

The development of a clinical interface for a novel newborn resuscitation device; a Human Factors approach to understand cognitive user requirements (2018)
Working Paper
Pickup, L., Lang, A., Shipley, L., Henry, C., Carpenter, J., McCartney, D., …Sharkey, D. The development of a clinical interface for a novel newborn resuscitation device; a Human Factors approach to understand cognitive user requirements

Background: A novel medical device has been developed to address an unmet need of standardizing and facilitating heart rate recording during neonatal resuscitation. In a time-critical emergency resuscitation, where failure can mean death of an in... Read More about The development of a clinical interface for a novel newborn resuscitation device; a Human Factors approach to understand cognitive user requirements.

Gene-Based Analysis in HRC Imputed Genome Wide Association Data Identifies Three Novel Genes For Alzheimer’s Disease (2018)
Working Paper
Baker, E., Sims, R., Leonenko, G., Frizzati, A., Harwood, J., Grozeva, D., …EADI Consortium. Gene-Based Analysis in HRC Imputed Genome Wide Association Data Identifies Three Novel Genes For Alzheimer’s Disease

A novel POLARIS gene-based analysis approach was employed to compute gene-based polygenic risk score (PRS) for all individuals in the latest HRC imputed GERAD (N cases=3332 and N controls=9,832) data using the International Genomics of Alzheimer's Pr... Read More about Gene-Based Analysis in HRC Imputed Genome Wide Association Data Identifies Three Novel Genes For Alzheimer’s Disease.

Holographic optical trapping Raman micro-spectroscopy for interacting live cells (2018)
Working Paper
Sinjab, F., Elsheikha, H. M., Awuah, D., Gibson, G., Padgett, M., Ghaemmaghami, A. M., & Notingher, I. Holographic optical trapping Raman micro-spectroscopy for interacting live cells

We present a combined holographic optical tweezers and confocal Raman spectroscopy instrument which allows fast, flexible, and interactive manipulation with molecular measurement of interacting live cell systems. Multiple laser foci created using a s... Read More about Holographic optical trapping Raman micro-spectroscopy for interacting live cells.

Three-dimensional plant architecture and sunlit-shaded patterns: a stochastic model of light dynamics in canopies (2018)
Working Paper
Retkute, R., Townsend, A. J., Murchie, E. H., Jensen, O. E., & Preston, S. P. Three-dimensional plant architecture and sunlit-shaded patterns: a stochastic model of light dynamics in canopies

Background and Aims Diurnal changes in solar position and intensity combined with the structural complexity of plant architecture result in highly variable and dynamic light patterns within the plant canopy. This affects productivity through the comp... Read More about Three-dimensional plant architecture and sunlit-shaded patterns: a stochastic model of light dynamics in canopies.

Civil service management in developing countries: what works?: evidence from a survey with 23,000 civil servants in Africa, Asia, Eastn Europe and Latin America (2018)
Working Paper
Meyer-Sahling, J., Schuster, C., & Sass Mikkelsen, K. Civil service management in developing countries: what works?: evidence from a survey with 23,000 civil servants in Africa, Asia, Eastn Europe and Latin America

Civil servants are central to effective governance in developing countries. They deliver essential services to citizens, commission infrastructure, regulate economic activity and engage in diplomacy with foreign countries – to name just a few tasks.... Read More about Civil service management in developing countries: what works?: evidence from a survey with 23,000 civil servants in Africa, Asia, Eastn Europe and Latin America.