Research Repository

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A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli (2019)
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Cogger-Ward, R., Collins, A., McLean, D., Dehinsilu, J., & Huett, A. (2019). A conserved protein, BcmA, mediates motility, biofilm formation, and host colonisation in Adherent Invasive Escherichia coli

Adherent Invasive Escherichia coli (AIEC) is a non-diarrhoeagenic intestinal E. coli pathotype associated with Crohn’s Disease. AIEC pathogenesis is characterised by biofilm formation, adhesion to and invasion of intestinal epithelial cells, and intr... Read More

Whole genome duplication potentiates inter-specific hybridisation and niche shifts in Australian burrowing frogs Neobatrachus (2019)
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Novikova, P. Y., Brennan, I. G., Booker, W., Mahony, M., Doughty, P., Lemmon, A. R., …Donnellan, S. C. (2019). Whole genome duplication potentiates inter-specific hybridisation and niche shifts in Australian burrowing frogs Neobatrachus

Polyploidy plays an important role in evolution because it can lead to increased genetic complexity and speciation. It also provides an extra copy buffer and increases genetic novelty. While both common and well-studied in plants, polyploidy is rare... Read More

Identification of nitrogen-dependent QTL and underlying genes for root system architecture in hexaploid wheat (2019)
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Griffiths, M., Atkinson, J. A., Gardiner, L., Swarup, R., Pound, M. P., Wilson, M. H., …Wells, D. M. (2019). Identification of nitrogen-dependent QTL and underlying genes for root system architecture in hexaploid wheat

The root system architecture (RSA) of a crop has a profound effect on the uptake of nutrients and consequently the potential yield. However, little is known about the genetic basis of RSA and resource dependent response in wheat (Triticum aestivum L.... Read More

Mitochondrial respiratory states and rates (2019)
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Gnaiger, E., & Chakrabarti, L. (2019). Mitochondrial respiratory states and rates

As the knowledge base and importance of mitochondrial physiology to human health expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory es... Read More

The Bible in the Work of J.K. Rowling (2018)
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Parks, S. (2018). The Bible in the Work of J.K. Rowling

Oxford Biblical Studies Online is an online subscription-based educational resource by Oxford University Press. This piece is part of their "Bible and Literature" series. It covers the influence of the Bible in the Harry Potter series by J. K. Rowlin... Read More

Patient reported distress can aid clinical decision making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort (2018)
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Stewart, I., McKeever, T., Braybrooke, R., Oballa, E., Simpson, J. K., Maher, T. M., …Saini, G. (2018). Patient reported distress can aid clinical decision making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort

Idiopathic pulmonary fibrosis is a progressive and fatal interstitial lung disease. We aimed to determine if patient response to a palliative assessment survey could predict disease progression or death. We undertook a cross-sectional study in a U... Read More

Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche: (2018)
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Prina, E., Sidney, L., Tromayer, M., Moore, J., Liska, R., Bertolin, M., …Rose, F. R. (2018). Geometry alone influences stem cell differentiation in a precision 3D printed stem cell niche:

Stem cells within epithelial tissues reside in anatomical structures known as crypts that are known to contribute to the mechanical and chemical milieu important for function. To date, epithelial stem cell therapies have largely ignored the niche and... Read More

Occupiers’ liability: the enactment of ‘common law’ principles (2018)
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Bailey, S. (2018). Occupiers’ liability: the enactment of ‘common law’ principles. Unpublished in this form

This paper considers the development of the common law of occupier's liability and the processes that led to the enactment of, and the content of, the Occupier's Liability Acts of 1957 and 1984. [This paper first written April 2011. An edited ver... Read More

Gsmodutils: A python based framework for test-driven genome scale metabolic model development (2018)
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Gilbert, J. P., Pearcy, N., Norman, R., Millat, T., Winzer, K., King, J., …Twycross, J. (2018). Gsmodutils: A python based framework for test-driven genome scale metabolic model development

Motivation Genome scale metabolic models (GSMMs) are increasingly important for systems biology and metabolic engineering research as they are capable of simulating complex steady-state behaviour. Constraints based models of this form can include tho... Read More

Wireless bioelectronic nanosystems for intracellular communication (2018)
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Sanjuán-Alberte, P., Abayzeed, S. A., Fuentes-Domínguez, R., Alea-Reyesd, M. E., Clark, M., Hague, R., …Rawson, F. (2018). Wireless bioelectronic nanosystems for intracellular communication

In order for the field of bioelectronics to make an impact on healthcare, there is an urgent requirement for the development of “wireless” electronic systems to both sense and actuate cell behaviour. Herein we report the first example of an innovativ... Read More

Surface Plasmon Resonance Imaging of Excitable Cells (2018)
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Howe, C. L., Webb, K. F., Abayzeed, S. A., Anderson, D. J., Denning, C., & Russell, N. A. (2018). Surface Plasmon Resonance Imaging of Excitable Cells

Surface plasmons are highly sensitive to refractive index variations adjacent to the surface. This sensitivity has been exploited successfully for chemical and biological assays. In these systems, a surface plasmon resonance (SPR)-based sensor detect... Read More

Demanding the impossible: a strike zine (2018)
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Legg, S., Clare, N., Field, R., Forsyth, I., Freeman, C., French, S., …Soccorsy, E. (2018). Demanding the impossible: a strike zine

A co-authored and co-curated series of reflections on the 2018 UCU strikes in British Universities, protesting against proposed pension reforms.

The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study (Preprint) (2018)
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Dewey, R. S., Hall, D. A., Guest, H., Prendergast, G., Plack, C. J., & Francis, S. T. (2018). The Physiological Bases of Hidden Noise-Induced Hearing Loss: Protocol for a Functional Neuroimaging Study (Preprint)

Background: Rodent studies indicate that noise exposure can cause permanent damage to synapses between inner hair cells and high-threshold auditory nerve fibers, without permanently altering threshold sensitivity. These demonstrations of what is c... Read More