All Outputs (37)

Moving magnetoencephalography towards real-world applications with a wearable system (2018)
Journal Article
Boto, E., Holmes, N., Leggett, J., Roberts, G., Shah, V., Meyer, S. S., …Brookes, M. J. (2018). Moving magnetoencephalography towards real-world applications with a wearable system. Nature, 555, 657-661. https://doi.org/10.1038/nature26147

Imaging human brain function with techniques such as magnetoencephalography1 (MEG) typically requires a subject to perform tasks whilst their head remains still within a restrictive scanner. This artificial environment makes the technique inaccessibl... Read More about Moving magnetoencephalography towards real-world applications with a wearable system.

Exploring the origins of EEG motion artefacts during simultaneous fMRI acquisition: implications for motion artefact correction (2018)
Journal Article
Spencer, G. S., Smith, J. A., Chowdhury, M. E., Bowtell, R. W., & Mullinger, K. J. (in press). Exploring the origins of EEG motion artefacts during simultaneous fMRI acquisition: implications for motion artefact correction. NeuroImage, 173, https://doi.org/10.1016/j.neuroimage.2018.02.034

Motion artefacts (MAs) are induced within EEG data collected simultaneously with fMRI when the subject’s head rotates relative to the magnetic field. The effects of these artefacts have generally been ameliorated by removing periods of data during wh... Read More about Exploring the origins of EEG motion artefacts during simultaneous fMRI acquisition: implications for motion artefact correction.

Exploring the advantages of multiband fMRI with simultaneous EEG to investigate coupling between gamma frequency neural activity and the BOLD response in humans (2018)
Journal Article
Uji, M., Wilson, R., Francis, S. T., Mullinger, K. J., & Mayhew, S. D. (2018). Exploring the advantages of multiband fMRI with simultaneous EEG to investigate coupling between gamma frequency neural activity and the BOLD response in humans. Human Brain Mapping, 39(4), 1673-1687. https://doi.org/10.1002/hbm.23943

We established an optimal combination of EEG recording during sparse multiband (MB) fMRI that preserves high resolution, whole brain fMRI coverage whilst enabling broad-band EEG recordings which are uncorrupted by MRI gradient artefacts (GAs). We fir... Read More about Exploring the advantages of multiband fMRI with simultaneous EEG to investigate coupling between gamma frequency neural activity and the BOLD response in humans.

Decoding fMRI events in sensorimotor motor network using sparse paradigm free mapping and activation likelihood estimates: Decoding fMRI Events in SMN (2017)
Journal Article
Tan, F. M., Caballero-Gaudes, C., Mullinger, K. J., Cho, S., Zhang, Y., Dryden, I. L., …Gowland, P. A. (2017). Decoding fMRI events in sensorimotor motor network using sparse paradigm free mapping and activation likelihood estimates: Decoding fMRI Events in SMN. Human Brain Mapping, 38(11), 5778-5794. https://doi.org/10.1002/hbm.23767

Most functional MRI (fMRI) studies map task-driven brain activity using a block or event-related paradigm. Sparse paradigm free mapping (SPFM) can detect the onset and spatial distribution of BOLD events in the brain without prior timing information,... Read More about Decoding fMRI events in sensorimotor motor network using sparse paradigm free mapping and activation likelihood estimates: Decoding fMRI Events in SMN.

Spatiotemporal neural characterization of prediction error valence and surprise during reward learning in humans (2017)
Journal Article
Fouragnan, E., Queirazza, F., Retzler, C., Mullinger, K. J., & Philiastides, M. G. (in press). Spatiotemporal neural characterization of prediction error valence and surprise during reward learning in humans. Scientific Reports, 7, Article 4762. https://doi.org/10.1038/s41598-017-04507-w

Reward learning depends on accurate reward associations with potential choices. These associations can be attained with reinforcement learning mechanisms using a reward prediction error (RPE) signal (the difference between actual and expected rewards... Read More about Spatiotemporal neural characterization of prediction error valence and surprise during reward learning in humans.

Post-stimulus fMRI and EEG responses: evidence for a neuronal origin hypothesised to be inhibitory (2017)
Journal Article
Mullinger, K. J., Cherukara, M. T., Buxton, R. B., Francis, S. T., & Mayhew, S. D. (2017). Post-stimulus fMRI and EEG responses: evidence for a neuronal origin hypothesised to be inhibitory. NeuroImage, 157, https://doi.org/10.1016/j.neuroimage.2017.06.020

Post-stimulus undershoots, negative responses following cessation of stimulation, are widely observed in functional magnetic resonance (fMRI) blood oxygenation level dependent (BOLD) data. However, the debate surrounding whether the origin of this re... Read More about Post-stimulus fMRI and EEG responses: evidence for a neuronal origin hypothesised to be inhibitory.

The effect of physical fatigue on oscillatory dynamics of the sensorimotor cortex (2017)
Journal Article
Fry, A., Mullinger, K. J., O'Neill, G. C., Brookes, M. J., & Folland, J. P. (2018). The effect of physical fatigue on oscillatory dynamics of the sensorimotor cortex. Acta Physiologica, 220(3), 370-381. https://doi.org/10.1111/apha.12843

Aim: While physical fatigue is known to arise in part from supraspinal mechanisms within the brain exactly how brain activity is modulated during fatigue is not well understood. Therefore, this study examined how typical neural oscillatory responses... Read More about The effect of physical fatigue on oscillatory dynamics of the sensorimotor cortex.

Modulation of post-movement beta rebound by contraction force and rate of force development (2016)
Journal Article
Fry, A., Mullinger, K. J., O'Neill, G. C., Barratt, E. L., Morris, P. G., Bauer, M., …Brookes, M. J. (2016). Modulation of post-movement beta rebound by contraction force and rate of force development. Human Brain Mapping, 37(7), https://doi.org/10.1002/hbm.23189

Movement induced modulation of the beta rhythm is one of the most robust neural oscillatory phenomena in the brain. In the preparation and execution phases of movement, a loss in beta amplitude is observed (movement related beta decrease (MRBD)). Thi... Read More about Modulation of post-movement beta rebound by contraction force and rate of force development.

Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement (2016)
Journal Article
Fellner, M., Volberg, G., Mullinger, K., Goldhacker, M., Wimber, M., Greenlee, M., & Hanslmayr, S. (2016). Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement. NeuroImage, 133, https://doi.org/10.1016/j.neuroimage.2016.03.031

Simultaneous EEG-fMRI provides an increasingly attractive research tool to investigate cognitive processes with high temporal and spatial resolution. However, artifacts in EEG data introduced by the MR-scanner still remain a major obstacle. This stud... Read More about Spurious correlations in simultaneous EEG-fMRI driven by in-scanner movement.

Global signal modulation of single-trial fMRI response variability: effect on positive vs negative BOLD response relationship (2016)
Journal Article
Mayhew, S. D., Mullinger, K. J., Ostwald, D., Porcaro, C., Bowtell, R. W., Bagshaw, A. P., & Francis, S. T. (2016). Global signal modulation of single-trial fMRI response variability: effect on positive vs negative BOLD response relationship. NeuroImage, 133, https://doi.org/10.1016/j.neuroimage.2016.02.077

In functional magnetic resonance imaging (fMRI), the relationship between positive BOLD responses (PBRs) and negative BOLD responses (NBRs) to stimulation is potentially informative about the balance of excitatory and inhibitory brain responses in se... Read More about Global signal modulation of single-trial fMRI response variability: effect on positive vs negative BOLD response relationship.

Two spatiotemporally distinct value systems shape reward-based learning in the human brain (2015)
Journal Article
Fouragnan, E., Retzler, C., Mullinger, K. J., & Philiastides, M. G. (2015). Two spatiotemporally distinct value systems shape reward-based learning in the human brain. Nature Communications, 6(8107), https://doi.org/10.1038/ncomms9107

Avoiding repeated mistakes and learning to reinforce rewarding decisions is critical for human survival and adaptive actions. Yet, the neural underpinnings of the value systems that encode different decision-outcomes remain elusive. Here coupling sin... Read More about Two spatiotemporally distinct value systems shape reward-based learning in the human brain.

Evidence that the negative BOLD response is neuronal in origin: a simultaneous EEG–BOLD–CBF study in humans (2014)
Journal Article
Mullinger, K. J., Mayhew, S. D., Bagshaw, A. P., Bowtell, R. W., & Francis, S. T. (2014). Evidence that the negative BOLD response is neuronal in origin: a simultaneous EEG–BOLD–CBF study in humans. NeuroImage, 94, https://doi.org/10.1016/j.neuroimage.2014.02.029

Unambiguous interpretation of changes in the BOLD signal is challenging because of the complex neurovascular coupling that translates changes in neuronal activity into the subsequent haemodynamic response. In particular, the neurophysiological origin... Read More about Evidence that the negative BOLD response is neuronal in origin: a simultaneous EEG–BOLD–CBF study in humans.

Reference layer artefact subtraction (RLAS): A novel method of minimizing EEG artefacts during simultaneous fMRI (2013)
Journal Article
Chowdhury, M. E., Mullinger, K. J., Glover, P., & Bowtell, R. W. (2014). Reference layer artefact subtraction (RLAS): A novel method of minimizing EEG artefacts during simultaneous fMRI. NeuroImage, 84, 307-319. https://doi.org/10.1016/j.neuroimage.2013.08.039

Large artefacts compromise EEG data quality during simultaneous fMRI. These artefact voltages pose heavy demands on the bandwidth and dynamic range of EEG amplifiers and mean that even small fractional variations in the artefact voltages give rise to... Read More about Reference layer artefact subtraction (RLAS): A novel method of minimizing EEG artefacts during simultaneous fMRI.

Poststimulus undershoots in cerebral blood flow and BOLD fMRI responses are modulated by poststimulus neuronal activity (2013)
Journal Article
Mullinger, K. J., Mayhew, S. D., Bagshaw, A. P., Bowtell, R., & Francis, S. T. (2013). Poststimulus undershoots in cerebral blood flow and BOLD fMRI responses are modulated by poststimulus neuronal activity. Proceedings of the National Academy of Sciences, 110(33), https://doi.org/10.1073/pnas.1221287110

fMRI is the foremost technique for noninvasive measurement of human brain function. However, its utility is limited by an incomplete understanding of the relationship between neuronal activity and the hemodynamic response. Though the primary peak of... Read More about Poststimulus undershoots in cerebral blood flow and BOLD fMRI responses are modulated by poststimulus neuronal activity.

Identifying the sources of the pulse artefact in EEG recordings made inside an MR scanner (2013)
Journal Article
Mullinger, K. J., Havenhand, J., & Bowtell, R. W. (2013). Identifying the sources of the pulse artefact in EEG recordings made inside an MR scanner. NeuroImage, 71(1), https://doi.org/10.1016/j.neuroimage.2012.12.070

EEG recordings made during concurrent fMRI are confounded by the pulse artefact (PA), which although smaller than the gradient artefact is often more problematic because of its variability over multiple cardiac cycles. A better understanding of the P... Read More about Identifying the sources of the pulse artefact in EEG recordings made inside an MR scanner.

Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data (2012)
Journal Article
Jansen, M., White, T. P., Mullinger, K. J., Liddle, E. B., Gowland, P. A., Francis, S. T., …Liddle, P. F. (2012). Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data. NeuroImage, 59(1), https://doi.org/10.1016/j.neuroimage.2011.06.094

The simultaneous acquisition and subsequent analysis of EEG and fMRI data is challenging owing to increased noise levels in the EEG data. A common method to integrate data from these two modalities is to use aspects of the EEG data, such as the ampli... Read More about Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data.

Reducing the gradient artefact in simultaneous EEG-fMRI by adjusting the subject’s axial position (2011)
Journal Article
Mullinger, K. J., Yan, W. X., & Bowtell, R. W. (2011). Reducing the gradient artefact in simultaneous EEG-fMRI by adjusting the subject’s axial position. NeuroImage, 54(3), https://doi.org/10.1016/j.neuroimage.2010.09.079

Large artefacts which compromise EEG data quality are generated when electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) are carried out concurrently. The gradient artefact produced by the time-varying magnetic field gradien... Read More about Reducing the gradient artefact in simultaneous EEG-fMRI by adjusting the subject’s axial position.