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Accurate position tracking of optically trapped live cells (2014)
Journal Article
McAlinden, N., Glass, D. G., Millington, O. R., & Wright, A. J. (2014). Accurate position tracking of optically trapped live cells. Biomedical Optics Express, 5(4), https://doi.org/10.1364/BOE.5.001026

Optical trapping is a powerful tool in Life Science research and is becoming common place in many microscopy laboratories and facilities. There is a growing need to directly trap the cells of interest rather than introduce beads to the sample that ca... Read More about Accurate position tracking of optically trapped live cells.

Strategies to overcome photobleaching in algorithm-based adaptive optics for nonlinearin-vivoimaging (2014)
Journal Article
Müllenbroich, M. C., McGhee, E. J., Wright, A. J., Anderson, K. I., & Mathieson, K. (2014). Strategies to overcome photobleaching in algorithm-based adaptive optics for nonlinearin-vivoimaging. Journal of Biomedical Optics, 19(1), Article 016021. https://doi.org/10.1117/1.JBO.19.1.016021

We have developed a nonlinear adaptive optics microscope utilizing a deformable membrane mirror (DMM) and demonstrated its use in compensating for system- and sample-induced aberrations. The optimum shape of the DMM was determined with a random searc... Read More about Strategies to overcome photobleaching in algorithm-based adaptive optics for nonlinearin-vivoimaging.

Investigating the microrheology of the vitreous humor using an optically trapped local probe (2013)
Journal Article
Watts, F., Tan, L. E., Wilson, C. G., Girkin, J. M., Tassieri, M., & Wright, A. J. (2013). Investigating the microrheology of the vitreous humor using an optically trapped local probe. Journal of Optics, 16(1), https://doi.org/10.1088/2040-8978/16/1/015301

We demonstrate that an optically trapped silica bead can be used as a local probe to measure the micro-rheology of the vitreous humor. The Brownian motion of the bead was observed using a fast camera and the micro-rheology determined by analysis of t... Read More about Investigating the microrheology of the vitreous humor using an optically trapped local probe.