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All Outputs (4)

Publishers, Funders and Institutions: Who is supporting UKRI funded researchers to share data? (2023)
Journal Article
Montague-Hellen, B., & Montague-Hellen, K. (2023). Publishers, Funders and Institutions: Who is supporting UKRI funded researchers to share data?. Insights, 36, Article 4. https://doi.org/10.1629/uksg.602

Researchers are increasingly being asked by funders, publishers and their institutions to share research data alongside written publications, and to included data availability statements to support their readers in finding this data. In the UK UKRI i... Read More about Publishers, Funders and Institutions: Who is supporting UKRI funded researchers to share data?.

Alu elements in primates are preferentially lost from areas of high GC content (2013)
Journal Article
Hellen, E. H., & Brookfield, J. F. (2013). Alu elements in primates are preferentially lost from areas of high GC content. PeerJ, 1(1), e78. https://doi.org/10.7717/peerj.78

The currently-accepted dogma when analysing human Alu transposable elements is that 'young' Alu elements are found in low GC regions and 'old' Alus in high GC regions. The correlation between high GC regions and high gene frequency regions make this... Read More about Alu elements in primates are preferentially lost from areas of high GC content.

The diversity of Class II transposable elements in mammalian genomes has arisen from ancestral phylogenetic splits during ancient waves of proliferation through the genome (2012)
Journal Article
Hellen, E. H., & Brookfield, J. F. (2012). The diversity of Class II transposable elements in mammalian genomes has arisen from ancestral phylogenetic splits during ancient waves of proliferation through the genome. Molecular Biology and Evolution, 30(1), https://doi.org/10.1093/molbev/mss206

DNA transposons make up three percent of the human genome, roughly the same percentage as genes. However, due to their inactivity, they are often ignored in favour of the more abundant, active, retroelements. Despite this relative ignominy, there are... Read More about The diversity of Class II transposable elements in mammalian genomes has arisen from ancestral phylogenetic splits during ancient waves of proliferation through the genome.

Investigation of the origin and spread of a mammalian transposable element based on current sequence diversity (2011)
Journal Article
Hellen, E. H., & Brookfield, J. F. (2011). Investigation of the origin and spread of a mammalian transposable element based on current sequence diversity. Journal of Molecular Evolution, 73(5-6), https://doi.org/10.1007/s00239-011-9475-y

Almost half the human genome consists of mobile DNA elements, and their analysis is a vital part of understanding the human genome as a whole. Many of these elements are ancient and have persisted in the genome for tens or hundreds of millions of yea... Read More about Investigation of the origin and spread of a mammalian transposable element based on current sequence diversity.