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All Outputs (17)

Repeat patient testing-quality control compared to commercial quality control material for the Sysmex XT-2000iV hematology analyzer in a multi-site veterinary laboratory (2024)
Journal Article
Daly, S., Rishniw, M., Graham, P. A., & Freeman, K. P. (2024). Repeat patient testing-quality control compared to commercial quality control material for the Sysmex XT-2000iV hematology analyzer in a multi-site veterinary laboratory. Veterinary Clinical Pathology, 53(S1), 48-59. https://doi.org/10.1111/vcp.13332

Background: Quality control material (QCM) for hematology in veterinary laboratories is limited, and repeat patient testing quality control (RPT‐QC) is an alternative method using excess matrix‐specific samples. Objectives: This study aimed to determ... Read More about Repeat patient testing-quality control compared to commercial quality control material for the Sysmex XT-2000iV hematology analyzer in a multi-site veterinary laboratory.

Repeat patient testing-quality control with canine samples shows promise as an alternative to commercial quality control material for a network of 4 Sysmex XT2000iV hematology analyzers (2023)
Journal Article
Daly, S., Graham, P., & Freeman, K. P. (2023). Repeat patient testing-quality control with canine samples shows promise as an alternative to commercial quality control material for a network of 4 Sysmex XT2000iV hematology analyzers. Veterinary Clinical Pathology, https://doi.org/10.1111/vcp.13211

Background Repeat patient testing-quality control (RPT-QC) uses retained patient samples as an alternative to commercial quality control material (QCM). We elected to calculate and validate RPT-QC limits for red blood cell count (RBC), hemoglobin (H... Read More about Repeat patient testing-quality control with canine samples shows promise as an alternative to commercial quality control material for a network of 4 Sysmex XT2000iV hematology analyzers.

Successful use of a benchtop fluorescent enzyme immunoassay analyzer to measure serum cortisol concentration as a screening test for hypoadrenocorticism in dogs (2022)
Journal Article
Bacon, J., Graham, P. A., Hrovat, A., Kilpatrick, S., Mann, N. O., & Swales, H. (2023). Successful use of a benchtop fluorescent enzyme immunoassay analyzer to measure serum cortisol concentration as a screening test for hypoadrenocorticism in dogs. Journal of the American Veterinary Medical Association, 261(1), 111-117. https://doi.org/10.2460/javma.22.08.0346

OBJECTIVE To assess the diagnostic performance of a benchtop fluorescent enzyme immunoassay analyzer (AIA-360; Tosoh Bioscience Inc) for the measurement of serum cortisol concentration as a screening test for hypoadrenocorticism in dogs. ANIMALS 173... Read More about Successful use of a benchtop fluorescent enzyme immunoassay analyzer to measure serum cortisol concentration as a screening test for hypoadrenocorticism in dogs.

Quality control validation for a veterinary laboratory network of six Sysmex XT-2000i/V hematology analyzers iV hematology analyzers (2022)
Journal Article
Daly, S., Graham, P. A., & Freeman, K. P. (2022). Quality control validation for a veterinary laboratory network of six Sysmex XT-2000i/V hematology analyzers iV hematology analyzers. Veterinary Clinical Pathology, 51(4), 565-576. https://doi.org/10.1111/vcp.13163

Background: Quality control (QC) validation is an important step in the laboratory harmonization process. This includes the application of statistical QC requirements, procedures, and control rules to identify and maintain ongoing stable analytical p... Read More about Quality control validation for a veterinary laboratory network of six Sysmex XT-2000i/V hematology analyzers iV hematology analyzers.

Evaluation of Sysmex XT-2000iV analyzer performance across a network of five veterinary laboratories using a commercially available quality control material (2021)
Journal Article
Daly, S., Freeman, K. P., & Graham, P. A. (2021). Evaluation of Sysmex XT-2000iV analyzer performance across a network of five veterinary laboratories using a commercially available quality control material. Veterinary Clinical Pathology, 50(4), 568-578. https://doi.org/10.1111/vcp.13016

Background Laboratory and instrument harmonization is seldom reported in the veterinary literature despite its advantages to clinical interpretation, including the use of interchangeable results and common reference intervals within a system of labo... Read More about Evaluation of Sysmex XT-2000iV analyzer performance across a network of five veterinary laboratories using a commercially available quality control material.

Results of urinary bacterial cultures and antibiotic susceptibility testing of dogs and cats in the UK (2021)
Journal Article
Fonseca, J., Mavrides, D., Graham, P., & McHugh, T. (2021). Results of urinary bacterial cultures and antibiotic susceptibility testing of dogs and cats in the UK. Journal of Small Animal Practice, 62(12), 1085-1091. https://doi.org/10.1111/jsap.13406

Objectives Bacterial urinary tract infections are a common diagnosis in small animal practice and antibiotics are often administered empirically. The aim of this study was to investigate the aetiology and antibiotic resistance of uropathogens in dog... Read More about Results of urinary bacterial cultures and antibiotic susceptibility testing of dogs and cats in the UK.

Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England (2021)
Journal Article
Mavrides, D. E., Morgan, A. L., Na, J. G., Graham, P. A., & McHugh, T. D. (2022). Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England. Veterinary Record, 190(4), Article e779. https://doi.org/10.1002/vetr.779

Background: Bacterial lower respiratory tract infections (bLRTIs) are common and potentially life threatening in cats and dogs. Antibiotic treatment is often initiated before the diagnosis of bLRTI; therefore improved knowledge of the aetiology and a... Read More about Antimicrobial resistance profiles of bacteria associated with lower respiratory tract infections in cats and dogs in England.

Comparison of 25?hydroxyvitamin D concentration in chimpanzee dried blood spots and serum (2020)
Journal Article
Moittié, S., Graham, P. A., Barlow, N., Dobbs, P., Liptovszky, M., Redrobe, S., & White, K. (2020). Comparison of 25‐hydroxyvitamin D concentration in chimpanzee dried blood spots and serum. Veterinary Clinical Pathology, 49(2), 299-306. https://doi.org/10.1111/vcp.12863

Background Dried blood spots (DBS) are used in human medicine to measure total 25‐hydroxyvitamin D (25‐OHD) in the blood. However, this easy and affordable sampling technique has not been evaluated in primates to measure vitamin D concentrations.... Read More about Comparison of 25?hydroxyvitamin D concentration in chimpanzee dried blood spots and serum.

Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism (2020)
Journal Article
Boag, A. M., Short, A., Kennedy, L. J., Syme, H., Graham, P. A., & Catchpole, B. (2020). Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism. Canine Medicine and Genetics, 7, Article 2. https://doi.org/10.1186/s40575-020-0081-4

Background Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison’s disease in humans. Several dog breeds are overrepresented in the disease population, suggesting t... Read More about Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism.

Pathological findings in the pituitary glands of 201 dogs and cats (2018)
Journal Article
Polledo, L., Grinwis, G. C., Graham, P., Dunning, M., & Baiker, K. (2018). Pathological findings in the pituitary glands of 201 dogs and cats. Veterinary Pathology, 55(6), 880-888. https://doi.org/10.1177/0300985818784162

With the exception of classic functional adenomas in dogs and horses, pituitary lesions are infrequently described in the veterinary literature. Approximately 10% of pituitary glands from asymptomatic humans contain abnormalities but the equivalent p... Read More about Pathological findings in the pituitary glands of 201 dogs and cats.

A longitudinal study of autoantibodies against cytochrome P450 side-chain cleavage enzyme in dogs (Canis lupus familiaris) affected with hypoadrenocorticism (Addison's disease) (2018)
Journal Article
Boag, A. M., Christie, M. R., McLaughlin, K. A., Syme, H. M., Graham, P., & Catchpole, B. (in press). A longitudinal study of autoantibodies against cytochrome P450 side-chain cleavage enzyme in dogs (Canis lupus familiaris) affected with hypoadrenocorticism (Addison's disease). Veterinary Immunology and Immunopathology, https://doi.org/10.1016/j.vetimm.2018.05.013

Autoantibodies directed against the P450 side chain cleavage enzyme (P450scc) have been recently described in dogs affected with hypoadrenocorticism, consistent with an immune-mediated pathogenesis of this endocrinopathy. In human autoimmune Addison’... Read More about A longitudinal study of autoantibodies against cytochrome P450 side-chain cleavage enzyme in dogs (Canis lupus familiaris) affected with hypoadrenocorticism (Addison's disease).

Hypophysitis, Panhypopituitarism, and Hypothalamitis in a Scottish Terrier Dog (2017)
Journal Article
Polledo, L., Oliveira, M., Adamany, J., Graham, P., & Baiker, K. (2017). Hypophysitis, Panhypopituitarism, and Hypothalamitis in a Scottish Terrier Dog. Journal of Veterinary Internal Medicine, 31(5), 1527-1532. https://doi.org/10.1111/jvim.14790

A 6-year old male neutered Scottish Terrier was referred with a 1 week history of progressive lethargy and anorexia. Neurological examination localized a lesion to the forebrain and hormonal testing showed panhypopituitarism. Magnetic resonance imagi... Read More about Hypophysitis, Panhypopituitarism, and Hypothalamitis in a Scottish Terrier Dog.

Mechanical, degradation and cytocompatibility properties of magnesium coated phosphate glass fibre reinforced polycaprolactone composites (2014)
Journal Article
Liu, X., Hasan, M. S., Grant, D. M., Harper, L. T., Parsons, A. J., Palmer, G., …Ahmed, I. (2014). Mechanical, degradation and cytocompatibility properties of magnesium coated phosphate glass fibre reinforced polycaprolactone composites. Journal of Biomaterials Applications, 29(5), https://doi.org/10.1177/0885328214541302

Retention of mechanical properties of phosphate glass fibre reinforced degradable polyesters such as polycaprolactone and polylactic acid in aqueous media has been shown to be strongly influenced by the integrity of the fibre/polymer interface. A pre... Read More about Mechanical, degradation and cytocompatibility properties of magnesium coated phosphate glass fibre reinforced polycaprolactone composites.

A second-generation ligand for the enantioselective rhodium-catalyzed addition of arylboronic acids to alkenylazaarenes (2014)
Journal Article
Roy, I. D., Burns, A. R., Pattison, G., Michel, B., Parker, A. J., & Lam, H. W. (2014). A second-generation ligand for the enantioselective rhodium-catalyzed addition of arylboronic acids to alkenylazaarenes. Chemical Communications, 50(22), https://doi.org/10.1039/C4CC00340C

A 2,4,6-trialkylanilide-containing chiral diene has been identified as a superior ligand for the enantioselective rhodiumcatalyzed arylation of alkenylazaarenes with arylboronic acids.