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A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour (2022)
Journal Article
Thompson, J. S., Hudson, C. D., Huxley, J. N., Kaler, J., Robinson, R. S., Woad, K. J., …Green, M. J. (2022). A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour. Scientific Reports, 12(1), Article 3849. https://doi.org/10.1038/s41598-022-07826-9

As a global society, we have a duty to provide suitable care and conditions for farmed livestock to protect animal welfare and ensure the sustainability of our food supply. The suitability and biological impacts of housing conditions for intensively... Read More about A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour.

Transforming growth factor-β1 disrupts angiogenesis during the follicular–luteal transition through the Smad–serpin family E member 1 (SERPINE1)/serpin family B member 5 (SERPINB5) signalling pathway in the cow (2021)
Journal Article
Yan, L., Qu, X., Yu, J., Robinson, B., Woad, K., & Shi, Z. (2021). Transforming growth factor-β1 disrupts angiogenesis during the follicular–luteal transition through the Smad–serpin family E member 1 (SERPINE1)/serpin family B member 5 (SERPINB5) signalling pathway in the cow. Reproduction, Fertility and Development, 33(10), 643-654. https://doi.org/10.1071/RD20325

Intense angiogenesis is critical for the development of the corpus luteum and is tightly regulated by numerous factors. However, the exact role transforming growth factor beta 1 (TGFB1) plays during this follicular-luteal transition remains unclear.... Read More about Transforming growth factor-β1 disrupts angiogenesis during the follicular–luteal transition through the Smad–serpin family E member 1 (SERPINE1)/serpin family B member 5 (SERPINB5) signalling pathway in the cow.

Maternal protein restriction affects fetal ovary development in sheep (2021)
Journal Article
Nwachukwu, C. U., Woad, K. J., Barnes, N., Gardner, D. S., & Robinson, R. S. (2021). Maternal protein restriction affects fetal ovary development in sheep. Reproduction and Fertility, 2(2), 161-171. https://doi.org/10.1530/raf-20-0073

Maternal malnutrition has important developmental consequences for the foetus. Indeed, adverse fetal ovarian development could have lifelong impact, with potentially reduced ovarian reserve and fertility of the offspring. This study investigated the... Read More about Maternal protein restriction affects fetal ovary development in sheep.

Characterisation of Listeria monocytogenes isolates from cattle using a bovine caruncular epithelial cell model (2020)
Journal Article
Blanchard, A. M., Billenness, R., Warren, J., Glanvill, A., Roden, W., Drinkall, E., …Tötemeyer, S. (2020). Characterisation of Listeria monocytogenes isolates from cattle using a bovine caruncular epithelial cell model. Heliyon, 6(7), Article e04476. https://doi.org/10.1016/j.heliyon.2020.e04476

© 2020 Listeria monocytogenes is an important foodborne pathogen in human and veterinary health, causing significant morbidity and mortality including abortion. It has a particular tropism for the gravid uterus, however, the route of infection in rep... Read More about Characterisation of Listeria monocytogenes isolates from cattle using a bovine caruncular epithelial cell model.

Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles (2019)
Journal Article
Mohammed, A., Woad, K. J., Mann, G. E., Craigon, J., Raine-Fenning, N., & Robinson, R. S. (2019). Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles. Fertility and Sterility, 112(3), 491-502.e3. https://doi.org/10.1016/j.fertnstert.2019.04.021

© 2019 American Society for Reproductive Medicine Objective: To evaluate the effectiveness of progestogen supplementation in improving clinical pregnancy rates in women undergoing fresh IVF cycles and to compare different routes, start times, duratio... Read More about Evaluation of progestogen supplementation for luteal phase support in fresh in vitro fertilization cycles.

Impact of endometritis on post-partum ovarian cyclicity in dairy cows (2019)
Journal Article
Mohammed, Z., Mann, G., & Robinson, R. (2019). Impact of endometritis on post-partum ovarian cyclicity in dairy cows. Veterinary Journal, 248, 8-13. https://doi.org/10.1016/j.tvjl.2019.03.008

Endometritis in dairy cows is a major global issue and has been associated with a decrease in reproductive performance. The aim of this study was to quantify the effect of endometritis (as defined by the presence of any abnormal vaginal discharge aft... Read More about Impact of endometritis on post-partum ovarian cyclicity in dairy cows.

Milk progesterone on day 5 following insemination in the dairy cow: associated metabolic variables and reproductive consequences (2018)
Journal Article
Yan, L. Y., Robinson, R. S., Shi, Z. D., & Mann, G. E. (2018). Milk progesterone on day 5 following insemination in the dairy cow: associated metabolic variables and reproductive consequences. South African Journal of Animal Science, 48(2), 361-368. https://doi.org/10.4314/sajas.v48i2.17

Despite the importance of progesterone on the fertility of lactating dairy cows, the factors that affect post ovulatory progesterone concentration are still unclear. Thus, the aim of the present study was to identify factors associated with the post... Read More about Milk progesterone on day 5 following insemination in the dairy cow: associated metabolic variables and reproductive consequences.

Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development (2017)
Journal Article
Metzler, V. M., de Brot, S., Robinson, R. S., Jeyapalan, J. N., Rakha, E., Walton, T., …Mongan, N. P. (2017). Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development. Placenta, 56, 79-85. https://doi.org/10.1016/j.placenta.2017.02.018

The placenta and tumors share important characteristics, including a requirement to establish effective angiogenesis. In the case of the placenta, optimal angiogenesis is required to sustain the blood flow required to maintain a successful pregnancy,... Read More about Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development.

Luteal angiogenesis and its control (2016)
Journal Article
Woad, K. J., & Robinson, R. S. (2016). Luteal angiogenesis and its control. Theriogenology, 86(1), 221-228. https://doi.org/10.1016/j.theriogenology.2016.04.035

Angiogenesis, the formation of new blood vessels from pre-existing ones, is critical to luteal structure and function; In addition, it is a complex and tightly regulated process. Not only does rapid and extensive angiogenesis occur to provide the cor... Read More about Luteal angiogenesis and its control.

Efficacy of progesterone supplementation during early pregnancy in cows: a meta-analysis (2015)
Journal Article
Yan, L., Robinson, R. S., Shi, Z., & Mann, G. E. (2016). Efficacy of progesterone supplementation during early pregnancy in cows: a meta-analysis. Theriogenology, 85(8), Article 1390-1398.e1. https://doi.org/10.1016/j.theriogenology.2015.12.027

Progesterone is a critical hormone during early pregnancy in the cow. As a result, a number of studies have investigated the effects of progesterone supplementation on pregnancy rates. In this study, a meta-analysis using a univariate binary random e... Read More about Efficacy of progesterone supplementation during early pregnancy in cows: a meta-analysis.

Novel gonadal characteristics in an aged bovine freemartin (2014)
Journal Article
Remnant, J., Lea, R. G., Allen, C. E., Huxley, J., Robinson, R. S., & Brower, A. (2014). Novel gonadal characteristics in an aged bovine freemartin. Animal Reproduction Science, 146(1-2), https://doi.org/10.1016/j.anireprosci.2014.02.011

The gonads from a five year old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against developmental and functional markers. We demonstrate, for the first time, the retention of anti-m... Read More about Novel gonadal characteristics in an aged bovine freemartin.

Mathematical analysis of a model for the growth of the bovine corpus luteum (2013)
Journal Article
Prokopiou, S. A., Byrne, H. M., Jeffrey, M. R., Robinson, R. S., Mann, G. E., & Owen, M. R. (2014). Mathematical analysis of a model for the growth of the bovine corpus luteum. Journal of Mathematical Biology, 69, 1515-1546. https://doi.org/10.1007/s00285-013-0722-2

© 2013, Springer-Verlag Berlin Heidelberg. The corpus luteum (CL) is an ovarian tissue that grows in the wound space created by follicular rupture. It produces the progesterone needed in the uterus to maintain pregnancy. Rapid growth of the CL and pr... Read More about Mathematical analysis of a model for the growth of the bovine corpus luteum.

The progesterone receptor antagonist, onapristone has differential effects on the timing and control of the luteolytic mechanism depending on timing of administration in sheep (2013)
Journal Article
Mann, G., Wathes, D., & Robinson, R. (2013). The progesterone receptor antagonist, onapristone has differential effects on the timing and control of the luteolytic mechanism depending on timing of administration in sheep. Molecular and Cellular Endocrinology, 376(1-2), 1-11. doi:10.1016/j.mce.2013.06.001

Cyclic ewes were treated with control vehicle or progesterone receptor antagonist (onapristone; 100 mg i.m. twice daily) during either early (day 3–5) or late (day 12–14) luteal phase and plasma samples collected for hormone analysis and to determine... Read More about The progesterone receptor antagonist, onapristone has differential effects on the timing and control of the luteolytic mechanism depending on timing of administration in sheep.