All Outputs (8)

A Hybrid Evolutionary Strategy to Optimise Early-Stage Cancer Screening (2019)
Conference Proceeding
Figueredo, G. P., Shi, P., Parkes, A. J., Evans, K., Garibaldi, J. M., Negm, O., …Robertson, J. (2019). A Hybrid Evolutionary Strategy to Optimise Early-Stage Cancer Screening. In 2019 IEEE Congress on Evolutionary Computation (CEC) (95-102). https://doi.org/10.1109/CEC.2019.8790316

Current methods to identify cutoff values for tumour-associated molecules (antigens) discrimination are based on statistics and brute force. These methods applied to cancer screening problems are very inefficient, especially with large data sets with... Read More about A Hybrid Evolutionary Strategy to Optimise Early-Stage Cancer Screening.

From clusters to queries: exploiting uncertainty in the modularity landscape of complex networks (2018)
Conference Proceeding
Gilbert, J. P., & Twycross, J. (2018). From clusters to queries: exploiting uncertainty in the modularity landscape of complex networks.

Uncovering latent community structure in complex networks is a field that has received an enormous amount of attention. Unfortunately, whilst potentially very powerful, unsupervised methods for uncovering labels based on topology alone has been shown... Read More about From clusters to queries: exploiting uncertainty in the modularity landscape of complex networks.

A low-cost paper-based model for on-chip human respiratory system studies (2016)
Conference Proceeding
Rahimi, R., Ochoa, M., Htwe, S. S., Donaldson, A., Zieger, M., Dokmeci, M. R., …Ziaie, B. (2016). A low-cost paper-based model for on-chip human respiratory system studies. In Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2016 (206-209). https://doi.org/10.31438/trf.hh2016.56

© 2016 TRF We present the use of hydrophobic paper as an effective semipermeable membrane, ideal for air-liquid interface cell culture applications. The surface properties of the paper is modified through selective CO2 laser-assisted scrubbing to cre... Read More about A low-cost paper-based model for on-chip human respiratory system studies.

Contribution of Ref(2)p to regulation of Drosophila notum epithelial cell apico-basal polarity and phenotype (2015)
Conference Proceeding
Shohayeb, B., Georgiou, M., & Layfield, R. (2015). Contribution of Ref(2)p to regulation of Drosophila notum epithelial cell apico-basal polarity and phenotype.

Cell polarity impacts on the maintenance of cell shape, cell-cell junction integrity, and protrusion formation and dynamics. Further, polarity additionally regulates cell movement, proliferation and differentiation. Conversely when cells lose their p... Read More about Contribution of Ref(2)p to regulation of Drosophila notum epithelial cell apico-basal polarity and phenotype.

A hybrid PDMS/paper passive pump for slow-release/delivery of drugs in chronic dermal wounds (2014)
Conference Proceeding
Rahimi, R., Ochoa, M., Zhou, J., Tamayol, A., Dokmeci, M. R., Khademhosseini, A., …Ziaie, B. (2014). A hybrid PDMS/paper passive pump for slow-release/delivery of drugs in chronic dermal wounds. In Proceedings of 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (2205-2207)

© 14CBMS. In this paper, we present a hybrid PDMS/paper-based passive pump for slow drug delivery in chronic wounds. The pump consists of a PDMS microfluidic network that is irreversibly bonded to the polyethylene-coated (hydrophobic) side of a comme... Read More about A hybrid PDMS/paper passive pump for slow-release/delivery of drugs in chronic dermal wounds.

A janus-paper PDMS platform for lab-on-a-chip applications (2014)
Conference Proceeding
Rahimi, R., Ochoa, M., Parupudi, T., Donaldson, A., Dokmeci, M. R., Khademhosseini, A., …Ziaie, B. (2014). A janus-paper PDMS platform for lab-on-a-chip applications. In Solid-State Sensors, Actuators, and Microsystems Workshop (119-122). https://doi.org/10.31438/trf.hh2014.34

© 2014TRF. A commercially available Janus paper with one hydrophobic (polyethylene-coated) face and a hygroscopic/hydrophilic one is irreversibly bonded to a PDMS substrate incorporating microfluidic channels via corona discharge surface treatment. T... Read More about A janus-paper PDMS platform for lab-on-a-chip applications.

Label-free separation and sorting of human monocytes and T-cells by electrowetting and dielectrophoresis (2013)
Conference Proceeding
Huang, C. Y., Chiang, M. Y., Fan, S. K., Ghaemmaghami, A. M., & Hsu, W. (2013). Label-free separation and sorting of human monocytes and T-cells by electrowetting and dielectrophoresis. In 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (873-876). https://doi.org/10.1109/NEMS.2013.6559863

We report a label-free separation and sorting approach based on electrowetting-on-dielectric (EWOD) and dielectrophoresis (DEP) to manipulate human monocyte (THP-1) and T-cell (Jurkat) lines in droplets without any impact on cell viability. In additi... Read More about Label-free separation and sorting of human monocytes and T-cells by electrowetting and dielectrophoresis.

Separation of dendritic and T cells using electrowetting and dielectrophoresis (2012)
Conference Proceeding
Chen, C. A., Chen, C. H., Ghaemmaghami, A. M., & Fan, S. K. (2012). Separation of dendritic and T cells using electrowetting and dielectrophoresis. In 2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) (183-186). https://doi.org/10.1109/NEMS.2012.6196752

The research of immune cells is fundamental to many biological studies. Dendritic cells have the ability to induce a primary immune response in resting naive T cells. The aim of this work is to separate the activated T cells from dendritic cells on a... Read More about Separation of dendritic and T cells using electrowetting and dielectrophoresis.