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Cell division cycle 25C (CDC25C) expression confers poor prognosis in invasive breast cancer (2017)
Conference Proceeding
Ojiegbe, S., Joseph, C., Provenzano, E., Caldas, C., Nolan, C., Green, A., …Mukherjee, A. (2017). Cell division cycle 25C (CDC25C) expression confers poor prognosis in invasive breast cancer

Background: CDC25C, belonging to the Cdc25 phosphatase family, plays a major role in cell cycle control, impacting on DNA repair and apoptosis. It has been shown that poor prognosis/copy number high Luminal A breast cancers (BCs) are enriched for the... Read More

Elevated expression of STK3 mRNA and protein is associated with poor outcome in invasive breast cancer (2017)
Conference Proceeding
Ojiegbe, S., Joseph, C., Provenzano, E., Caldas, C., Nolan, C., Green, A., …Mukherjee, A. (2017). Elevated expression of STK3 mRNA and protein is associated with poor outcome in invasive breast cancer

Purpose of the study: The mammalian sterile 20-like kinase (MST2/STK3) and its close homologue MST1(STK4) are members of the germinal centre kinase group II (GCK II) family of mitogen-activated protein kinases (MAPK). High STK3 expression is known to... Read More

Loss of MED23 leads to poor prognosis in invasive breast cancer (2017)
Conference Proceeding
Aliyeva, T., Joseph, C., Provenzano, E., Russell, R., Caldas, C., Sonbul, S., …Mukherjee, A. (2017). Loss of MED23 leads to poor prognosis in invasive breast cancer

Purpose of the study: The molecular mechanism of lymphovascular invasion (LVI) which determines the early metastatic phenotype in breast cancer is still not fully understood. Lead from the METABRIC study revealed that MED23 correlated with negative L... Read More

FOXP1 expression correlates with better prognosis in invasive breast cancer including the ER-positive luminal subtype (2017)
Conference Proceeding
Joseph, C., Craze, M. L., Nolan, C., Diez-Rodriguez, M., Green, A. R., Rakha, E., …Mukherjee, A. (2017). FOXP1 expression correlates with better prognosis in invasive breast cancer including the ER-positive luminal subtype

Background: Fork head box P1 (FOXP1) is a FOX family transcription factor influencing ERα;-regulated transcription by interaction with the ERα; related pioneer factor FOXA1. Altered FOXP1 expression is seen in breast and prostate cancers. This study... Read More

Investigation of human T cell responses to HPV16 E2 (2000)
Conference Proceeding
Davidson, E., Brown, M., Burt, D., Mulryan, K., Clayton, A., Gaston, K., …Stern, P. (2000). Investigation of human T cell responses to HPV16 E2. In The 18th International Papillomavirus Conference