All Outputs (3)

Phosphorylation of PRH/HHEX by Protein Kinase CK2 regulates cell proliferation and cell migration in diverse cell types (2018)
Book Chapter
Jayaraman, P., Wadey, K., George, S., & Gaston, K. (2018). Phosphorylation of PRH/HHEX by Protein Kinase CK2 regulates cell proliferation and cell migration in diverse cell types. In F. Uchiumi (Ed.), Gene expression and regulation in mammalian cells (237--255). InTech. https://doi.org/10.5772/intechopen.72902

Disruption of the regulatory mechanisms that control cell proliferation and cell migration results in multiple disease states including cancer and leukemia. The Proline-Rich Homeodomain protein (PRH)/haematopoietically expressed homeobox protein (HHE... Read More about Phosphorylation of PRH/HHEX by Protein Kinase CK2 regulates cell proliferation and cell migration in diverse cell types.

The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie (2012)
Book Chapter
Graham, S. V., & Gaston, K. L. (2012). The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie. In K. Gaston (Ed.), Small DNA tumour viruses, 37--53. Caister Academic Press

The human papillomavirus (HPV) genome is around 8000 base pairs in length and it encodes only eight proteins, a limited number of protein isoforms and no known microRNAs. Despite this relative paucity of genes and gene products these viruses are high... Read More about The regulation of human papillomavirus gene expression by the E2 protein: keeping a finger in every pie.

Measuring the induction or inhibition of apoptosis by HPV proteins (2005)
Book Chapter
Kowalczyk, A. M., Roeder, G. E., Green, K., Stephens, D. J., & Gaston, K. (2005). Measuring the induction or inhibition of apoptosis by HPV proteins. In C. Davy, & J. Doorbar (Eds.), Human Papillomaviruses: methods and protocols (419 -- 432). Totowa, NJ: Humana Press. https://doi.org/10.1385/1-59259-982-6%3A419

Many viral proteins influence the cellular pathways that control cell proliferation and cell death. Some viral proteins trigger apoptotic cell death, and this may be important in host defense and viral spread. In other cases, viral proteins inhibit a... Read More about Measuring the induction or inhibition of apoptosis by HPV proteins.