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Disruption of the human papillomavirus type 16 E2 gene protects cervical carcinoma cells from E2F-induced apoptosis (1997)
Journal Article
Sanchez-Perez, A.-M., Soriano, S., Clarke, A. R., & Gaston, K. (1997). Disruption of the human papillomavirus type 16 E2 gene protects cervical carcinoma cells from E2F-induced apoptosis. Journal of General Virology, 78(11), 3009-3018. https://doi.org/10.1099/0022-1317-78-11-3009

Human papillomavirus type 16 (HPV-16) is a DNA tumour virus that has been implicated in the development of cervical cancer. In non-transformed HPV-infected cells, the HPV E2 protein regulates transcription of the viral E6 and E7 oncogenes. Malignant... Read More about Disruption of the human papillomavirus type 16 E2 gene protects cervical carcinoma cells from E2F-induced apoptosis.

Partial shape matching using genetic algorithms (1997)
Journal Article
Ozcan, E., & Mohan, C. K. (1997). Partial shape matching using genetic algorithms. Pattern Recognition Letters, 18(10), 987-992. https://doi.org/10.1016/S0167-8655%2897%2900123-2

Shape recognition is a challenging task when images contain overlapping, noisy, occluded, partial shapes. This paper addresses the task of matching input shapes with model shapes described in terms of features such as line segments and angles. The qu... Read More about Partial shape matching using genetic algorithms.

A functional YY1 binding site is necessary and sufficient to activate Surf-1 promoter activity in response to serum growth factors (1997)
Journal Article
Cole, E. G., & Gaston, K. (1997). A functional YY1 binding site is necessary and sufficient to activate Surf-1 promoter activity in response to serum growth factors. Nucleic Acids Research, 25(18), 3705-3711. https://doi.org/10.1093/nar/25.18.3705

The human Surf-1 and Surf-2 housekeeping genes are divergently transcribed and share a bi-directional, TATA-less promoter. Housekeeping promoters typically contain complex arrays of transcription factor binding sites and several studies have suggeste... Read More about A functional YY1 binding site is necessary and sufficient to activate Surf-1 promoter activity in response to serum growth factors.

The molecular epidemiology of human immunodeficiency virus type 1 in six cities in Britain and Ireland (1997)
Journal Article
Brown, A. J., Lobidel, D., Wade, C. M., Rebus, S., Phillips, A. N., Brettle, R. P., France, A. J., Leen, C. S., McMenamin, J., McMillan, A., Maw, R. D., Mulcahy, F., Robertson, J. R., Sankar, K. N., Scott, G., Wyld, R., & Peutherer, J. F. (1997). The molecular epidemiology of human immunodeficiency virus type 1 in six cities in Britain and Ireland. Virology, 235(1), 166-177. https://doi.org/10.1006/viro.1997.8656

We have sequenced the p17 coding regions of the gag gene from 211 patients infected either through injecting drug use (IDU) or by sexual intercourse between men from six cities in Scotland, N. England, N. Ireland, and the Republic of Ireland. All seq... Read More about The molecular epidemiology of human immunodeficiency virus type 1 in six cities in Britain and Ireland.

Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease (1997)
Journal Article
Salvatori, F., Masiero, S., Giaquinto, C., Wade, C. M., Leigh Brown, A. J., Chieco-Bianchi, L., & De Rossi, A. (1997). Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease. Journal of Virology, 71(6), 4694-4706. https://doi.org/10.1128/jvi.71.6.4694-4706.1997

We addressed the relationship between the origin and evolution of human immunodeficiency virus type 1 (HIV-1) variants and disease outcome in perinatally infected infants by studying the V3 regions of viral variants in samples obtained from five tran... Read More about Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease.

Diet, smoking and exercise: Interrelationships between adolescent health behaviours (1997)
Journal Article
Coulson, N. S., Eiser, C., & Eiser, J. R. (1997). Diet, smoking and exercise: Interrelationships between adolescent health behaviours. Child: Care, Health and Development, 23(3), 207-216. https://doi.org/10.1111/j.1365-2214.1997.tb00964.x

A questionnaire measuring smoking status, exercise and dietary behaviour was administered to 932 high school pupils during regular classroom periods. Pupils were taken from three year groups which included 327 year 8 (12-13 years), 313 year 9 (13-14... Read More about Diet, smoking and exercise: Interrelationships between adolescent health behaviours.

Planktic foraminiferal molecular evolution and their polyphyletic origins from benthic taxa (1997)
Journal Article
Darling, K. F., Wade, C. M., Kroon, D., & Brown, A. J. (1997). Planktic foraminiferal molecular evolution and their polyphyletic origins from benthic taxa. Marine Micropaleontology, 30(4), 251-266. https://doi.org/10.1016/S0377-8398%2896%2900057-6

Phylogenetic analyses based on partial sequences of the small subunit (SSU) ribosomal (r) RNA gene have shown that the planktic and benthic foraminifera form a distinct monophyletic group within the eukaryotes. In order to determine the evolutionary... Read More about Planktic foraminiferal molecular evolution and their polyphyletic origins from benthic taxa.

DNA binding and bending by the human papillomavirus type 16 E2 protein: recognition of an extended binding site (1997)
Journal Article
Thain, A., Webster, K., Emery, D., Clarke, A. R., & Gaston, K. (1997). DNA binding and bending by the human papillomavirus type 16 E2 protein: recognition of an extended binding site. Journal of Biological Chemistry, 272(13), 8236-8242. https://doi.org/10.1074/jbc.272.13.8236

The human papillomavirus (HPV) 16 E2 protein (hE2) binds to four sites present upstream of the P97 promoter and regulates transcription of the viral E6 and E7 oncogenes. We have determined the relative binding constants for the interaction of the ful... Read More about DNA binding and bending by the human papillomavirus type 16 E2 protein: recognition of an extended binding site.

Predictions for pulsed-field-gradient NMR experiments of diffusion in fractal spaces (1997)
Journal Article
Damion, R., & Packer, K. (1997). Predictions for pulsed-field-gradient NMR experiments of diffusion in fractal spaces. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 453(1956), https://doi.org/10.1098/rspa.1997.0012

In this paper, theoretical predictions are made for pulsed-field-gradient NMR experiments of diffusion in fractal spaces. We obtain the general q-space behaviour of the NMR signal, which upon Fourier transformation, delivers the probability density f... Read More about Predictions for pulsed-field-gradient NMR experiments of diffusion in fractal spaces.

Sodomites in the pillory in eighteenth-century London (1997)
Journal Article
Bartlett, P. (1997). Sodomites in the pillory in eighteenth-century London. Social and Legal Studies, 6(4), https://doi.org/10.1177/096466399700600406

The arrival of the eighteenth century brought with it new legal attention to sodomitical behaviour. Nowhere was this more notorious and public than in the punishment of those offences in the pillory. This paper argues that the pillory was a product... Read More about Sodomites in the pillory in eighteenth-century London.

In vitro assessment of the influence of nutrition, temperature and larval density on trapping of the infective larvae of Heligmosomoides polygyrus by Arthrobotrys oligospora, Duddingtonia flagrans and Monacrosporium megalosporum (1997)
Journal Article
Morgan, M., Behnke, J. M., Lucas, J., & Peberdy, J. F. (1997). In vitro assessment of the influence of nutrition, temperature and larval density on trapping of the infective larvae of Heligmosomoides polygyrus by Arthrobotrys oligospora, Duddingtonia flagrans and Monacrosporium megalosporum. Parasitology, 115,

Making pupils fit the framework: Research into the implementation of the National Curriculum in schools for pupils with moderate learning difficulties, focusing on Key Stage 4 (1996)
Journal Article
Costley, D. (1996). Making pupils fit the framework: Research into the implementation of the National Curriculum in schools for pupils with moderate learning difficulties, focusing on Key Stage 4. School Leadership and Management, 16(3), 341-354. https://doi.org/10.1080/0260136960160308

The introduction of a National Curriculum in England and Wales caused a dilemma for many teachers who were responsible for pupils with learning difficulties. The issue of an entitlement curriculum for all pupils raised fundamental questions about the... Read More about Making pupils fit the framework: Research into the implementation of the National Curriculum in schools for pupils with moderate learning difficulties, focusing on Key Stage 4.

Early evolutionary origin of the planktic foraminifera inferred from small subunit rDNA sequence comparisons (1996)
Journal Article
Wade, C. M., Darling, K. F., Kroon, D., & Leigh Brown, A. J. (1996). Early evolutionary origin of the planktic foraminifera inferred from small subunit rDNA sequence comparisons. Journal of Molecular Evolution, 43(6), 672-677. https://doi.org/10.1007/BF02202115

Phylogenetic analysis of five partial planktic foraminiferal small subunit (SSU) ribosomal (r) DNA sequences with representatives of a diverse range of eukaryote, archaebacterial, and eubacterial taxa has revealed that the evolutionary origin of the... Read More about Early evolutionary origin of the planktic foraminifera inferred from small subunit rDNA sequence comparisons.

CpG methylation directly inhibits binding of the human papillomavirus type-16 E2 protein to specific DNA sequences (1996)
Journal Article
Thain, A., Jenkins, O., Clarke, A. R., & Gaston, K. (1996). CpG methylation directly inhibits binding of the human papillomavirus type-16 E2 protein to specific DNA sequences. Journal of Virology, 70(10), 7233-7235. https://doi.org/10.1128/jvi.70.10.7233-7235.1996

CpG methylation of the human papillomavirus upstream regulatory region has previously been shown to reduce virus promoter activity. Here, we demonstrate that methylation of the CpG dinucleotides contained within the binding site of the human papillom... Read More about CpG methylation directly inhibits binding of the human papillomavirus type-16 E2 protein to specific DNA sequences.

Molecular phylogeny of the planktic foraminifera (1996)
Journal Article
Darling, K. F., Kroon, D., Wade, C. M., & Leigh Brown, A. J. (1996). Molecular phylogeny of the planktic foraminifera. Journal of Foraminiferal Research, 26(4), 324-330. https://doi.org/10.2113/gsjfr.26.4.324

Planktic foraminifers are an important group of marine Zooplankton whose fossil record has been used extensively to reconstruct past climatic and oceanographic changes. Knowledge of the molecular phylogenetics of the planktic foraminifera will allow... Read More about Molecular phylogeny of the planktic foraminifera.