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All Outputs (111)

Automated prediction of mastitis infection patterns in dairy herds using machine learning (2020)
Journal Article
Hyde, R. M., Down, P. M., Bradley, A. J., Breen, J. E., Hudson, C., Leach, K. A., & Green, M. J. (2020). Automated prediction of mastitis infection patterns in dairy herds using machine learning. Scientific Reports, 10(1), https://doi.org/10.1038/s41598-020-61126-8

© 2020, The Author(s). Mastitis in dairy cattle is extremely costly both in economic and welfare terms and is one of the most significant drivers of antimicrobial usage in dairy cattle. A critical step in the prevention of mastitis is the diagnosis o... Read More about Automated prediction of mastitis infection patterns in dairy herds using machine learning.

Molecular detection of arthropod-borne pathogens in Eurasian badgers (Meles meles) from the United Kingdom (2020)
Journal Article
Guardone, L., Ebani, V. V., Verin, R., Nardoni, S., Consolazione, A., Bennett, M., & Mancianti, F. (2020). Molecular detection of arthropod-borne pathogens in Eurasian badgers (Meles meles) from the United Kingdom. Animals, 10(3), https://doi.org/10.3390/ani10030446

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Arthropod-borne diseases (ABD) are of increasing interest in veterinary and public health. Eurasian badgers (Meles meles) are known to harbor a wide range of pathogens, but information on thei... Read More about Molecular detection of arthropod-borne pathogens in Eurasian badgers (Meles meles) from the United Kingdom.

Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen PlusTM, for protected cell therapy applications (2020)
Journal Article
Finch, L., Harris, S., Solomou, G., Sen, J., Tzerakis, N., Emes, R. D., …Chari, D. M. (2020). Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen PlusTM, for protected cell therapy applications. Journal of Controlled Release, 321, 553-563. https://doi.org/10.1016/j.jconrel.2020.02.028

© 2020 Elsevier B.V. High transplant cell loss is a major barrier to translation of stem cell therapy for pathologies of the brain and spinal cord. Encapsulated delivery of stem cells in biomaterials for cell therapy is gaining popularity but experim... Read More about Safe nanoengineering and incorporation of transplant populations in a neurosurgical grade biomaterial, DuraGen PlusTM, for protected cell therapy applications.

Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation (2020)
Journal Article
Saminathan, M., Singh, K. P., Vineetha, S., Maity, M., Biswas, S. K., Manjunathareddy, G. B., …Mertens, P. P. C. (2020). Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation. Scientific Reports, 10(1), Article 2164. https://doi.org/10.1038/s41598-020-58268-0

© 2020, The Author(s). Transplacental transmission (TPT) of wild-type Indian BTV-1 had never been experimentally proved. This study was first time investigated TPT of Indian BTV-1 (isolated from aborted and stillborn goat fetal spleens). The sequenti... Read More about Virological, immunological and pathological findings of transplacentally transmitted bluetongue virus serotype 1 in IFNAR1-blocked mice during early and mid gestation.

Method for RNA extraction and transcriptomic analysis of single fungal spores (2019)
Journal Article
Geoghegan, I. A., Emes, R. D., Archer, D. B., & Avery, S. V. (2020). Method for RNA extraction and transcriptomic analysis of single fungal spores. MethodsX, 7, 50-55. https://doi.org/10.1016/j.mex.2019.12.002

Transcriptomic analysis of single cells has been increasingly in demand in recent years, thanks to technological and methodological advances as well as growing recognition of the importance of individuals in biological systems. However, the majority... Read More about Method for RNA extraction and transcriptomic analysis of single fungal spores.

Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo (2019)
Journal Article
Faidra Angelerou, M. G., Markus, R., Paraskevopoulou, V., Foralosso, R., Clarke, P., Alvarez, C. V., …Marlow, M. (2020). Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo. Journal of Controlled Release, 317, 118-129. https://doi.org/10.1016/j.jconrel.2019.10.011

Supramolecular gels have recently emerged as promising biomaterials for the delivery of a wide range of bioactive molecules, from small hydrophobic drugs to large biomolecules such as proteins. Although it has been demonstrated that each encapsulated... Read More about Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo.

Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses (2019)
Journal Article
Habershon?Butcher, J., Cutler, C., Viljanto, M., Hincks, P. R., Biddle, S., & Paine, S. W. (2020). Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses. Journal of Veterinary Pharmacology and Therapeutics, 43(1), 6-12. https://doi.org/10.1111/jvp.12820

© 2019 John Wiley & Sons Ltd Xylazine is widely used worldwide as a short-acting sedative in general equine and racing practice. In the UK, although it has a legitimate use during training, equine anti-doping rules state it is a prohibited substanc... Read More about Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses.

Assessment of costs and insurance policies for referral treatment of equine colic (2019)
Journal Article
Barker, I., & Freeman, S. L. (2019). Assessment of costs and insurance policies for referral treatment of equine colic. Veterinary Record, 185(16), 1-6. https://doi.org/10.1136/vr.105415

Colic is the most common emergency problem in horses. The aims of this study were to survey costs of different referral treatments and to review insurance policies relevant to horses with colic. Data were collected retrospectively from nine equine ho... Read More about Assessment of costs and insurance policies for referral treatment of equine colic.

Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition (2019)
Journal Article
Kletukhina, S., Neustroeva, O., James, V., Rizvanov, A., & Gomzikova, M. (2019). Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition. International Journal of Molecular Sciences, 20(19), https://doi.org/10.3390/ijms20194813

Epithelial-mesenchymal transition (EMT) is a process that takes place during embryonic development, wound healing, and under some pathological processes, including fibrosis and tumor progression. The molecular changes occurring within epithelial cell... Read More about Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition.

Copper physiology in ruminants: trafficking of systemic copper, adaptations to variation in nutritional supply and thiomolybdate challenge (2019)
Journal Article
Clarkson, A., Paine, S., Martín-Tereso, J., & Kendall, N. (2020). Copper physiology in ruminants: trafficking of systemic copper, adaptations to variation in nutritional supply and thiomolybdate challenge. Nutrition Research Reviews, 33(1), 43-49. https://doi.org/10.1017/S0954422419000180

Ruminants are recognised to suffer from Cu-responsive disorders. Present understanding of Cu transport and metabolism is limited and inconsistent across vets and veterinary professionals. There has been much progress from the studies of the 1980s and... Read More about Copper physiology in ruminants: trafficking of systemic copper, adaptations to variation in nutritional supply and thiomolybdate challenge.

Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse (2019)
Journal Article
Bowden, A., Burford, J., Brennan, M., England, G., & Freeman, S. (2019). Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse. Equine Veterinary Journal, https://doi.org/10.1111/evj.13173

Background Colic is the most common emergency problem in the horse. An owner’s ability to recognise colic and seek assistance is a critical first step in determining case outcome. Objectives The aim of this study was to assess horse owners’ know... Read More about Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse.

Key concepts for making informed choices (2019)
Journal Article
Aronson, J. K., Barends, E., Boruch, R., Brennan, M., Chalmers, I., Chislett, J., …Vale, L. (2019). Key concepts for making informed choices. Nature, 572(7769), 303-306. https://doi.org/10.1038/d41586-019-02407-9

An alliance of researchers lays out a framework for taking decisions based on thinking critically about claims and comparisons. Everyone makes claims about what works. Politicians claim that stop and search will reduce violent crime; friends claim th... Read More about Key concepts for making informed choices.

The multitasking Fasciola gigantica Cathepsin B interferes with various functions of goat peripheral blood mononuclear cells in vitro (2019)
Journal Article
Chen, D., Tian, A., Hou, J., Li, J., Tian, X., Yuan, X., …Zhu, X. (2019). The multitasking Fasciola gigantica Cathepsin B interferes with various functions of goat peripheral blood mononuclear cells in vitro. Frontiers in Immunology, 10, Article 1707. https://doi.org/10.3389/fimmu.2019.01707

Cathepsin B, a lysosomal cysteine protease, is thought to be involved in the pathogenesis of Fasciola gigantica infection, but its exact role remains unclear. In the present study, a recombinant F. gigantica cathepsin B (rFgCatB) protein was expresse... Read More about The multitasking Fasciola gigantica Cathepsin B interferes with various functions of goat peripheral blood mononuclear cells in vitro.

Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica (2019)
Journal Article
Kletenkov, K., Martynova, E., Davidyuk, Y., Kabwe, E., Shamsutdinov, A., Garanina, E., …Morzunov, S. (2019). Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica. Viruses, 11(7), Article 675. https://doi.org/10.3390/v11070675

Nephropathia Epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) and linked to hantavirus infection, is endemic in the Republic of Tatarstan. Several genetic markers of HFRS severity have been identified previously, including... Read More about Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica.

The future of cattle veterinary practice: insights from a qualitative study (2019)
Journal Article
Woodward, H., Cobb, K., & Remnant, J. (2019). The future of cattle veterinary practice: insights from a qualitative study. Veterinary Record, 185(7), https://doi.org/10.1136/vr.105321

The British livestock sector is constantly changing due to environmental and economic pressures, consequentially causing a shift in demand on farm veterinary services. The aim of this study was to explore the future of cattle veterinary practice, usi... Read More about The future of cattle veterinary practice: insights from a qualitative study.

Avian malaria-mediated population decline of a widespread iconic bird species (2019)
Journal Article
Dadum, D., Robinson, R., Clements, A., Peach, W., Bennett, M., Rowcliffe, J. M., & Cunningham, A. (2019). Avian malaria-mediated population decline of a widespread iconic bird species. Royal Society Open Science, 6(7), 182197. https://doi.org/10.1098/rsos.182197

Parasites have the capacity to affect animal populations by modifying host survival, and it is increasingly recognised that infectious disease can negatively impact biodiversity. Populations of the house sparrow (Passer domesticus) have declined in m... Read More about Avian malaria-mediated population decline of a widespread iconic bird species.

Physics of animal health: on the mechano-biology of hoof growth and form (2019)
Journal Article
Al-Agele, R., Paul, E., Taylor, S., Watson, C., Sturrock, C., Drakopoulos, M., …Rauch, C. (2019). Physics of animal health: on the mechano-biology of hoof growth and form. Interface, 16(155), 1-12. https://doi.org/10.1098/rsif.2019.0214

Global inequalities in economic access and agriculture productivity imply that a large number of developing countries rely on working equids for transport/agriculture/mining. Therefore, the understanding of hoof conditions/shape variations affecting... Read More about Physics of animal health: on the mechano-biology of hoof growth and form.