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All Outputs (111)

Machine Learning Algorithms to Classify and Quantify Multiple Behaviours in Dairy Calves Using a Sensor: Moving Beyond Classification in Precision Livestock (2020)
Journal Article
Carslake, C., Vázquez-Diosdado, J. A., & Kaler, J. (2021). Machine Learning Algorithms to Classify and Quantify Multiple Behaviours in Dairy Calves Using a Sensor: Moving Beyond Classification in Precision Livestock. Sensors, 21(1), 1-14. https://doi.org/10.3390/s21010088

Previous research has shown that sensors monitoring lying behaviours and feeding can detect early signs of ill health in calves. There is evidence to suggest that monitoring change in a single behaviour might not be enough for disease prediction. In... Read More about Machine Learning Algorithms to Classify and Quantify Multiple Behaviours in Dairy Calves Using a Sensor: Moving Beyond Classification in Precision Livestock.

Human gnathostomiasis: a neglected food-borne zoonosis (2020)
Journal Article
Liu, G., Sun, M., Elsheikha, H. M., Fu, Y., Sugiyama, H., Ando, K., …Yao, C. (2020). Human gnathostomiasis: a neglected food-borne zoonosis. Parasites and Vectors, 13, Article 616. https://doi.org/10.1186/s13071-020-04494-4

Background: Human gnathostomiasis is a food-borne zoonosis. Its etiological agents are the third-stage larvae of Gnathostoma spp. Human gnathostomiasis is often reported in developing countries, but it is also an emerging disease in developed countri... Read More about Human gnathostomiasis: a neglected food-borne zoonosis.

Methods for studying endocytotic pathways of herpesvirus encoded g protein-coupled receptors (2020)
Journal Article
Mavri, M., Spiess, K., Rosenkilde, M. M., Rutland, C. S., Vrecl, M., & Kubale, V. (2020). Methods for studying endocytotic pathways of herpesvirus encoded g protein-coupled receptors. Molecules, 25(23), Article 5710. https://doi.org/10.3390/molecules25235710

Endocytosis is a fundamental process involved in trafficking of various extracellular and transmembrane molecules from the cell surface to its interior. This enables cells to communicate and respond to external environments, maintain cellular homeost... Read More about Methods for studying endocytotic pathways of herpesvirus encoded g protein-coupled receptors.

Extracellular Vesicles: New Perspectives of Regenerative and Reproductive Veterinary Medicine (2020)
Journal Article
Zakirova, E. Y., Aimaletdinov, A. M., Malanyeva, A. G., Rutland, C. S., & Rizvanov, A. A. (2020). Extracellular Vesicles: New Perspectives of Regenerative and Reproductive Veterinary Medicine. Frontiers in Veterinary Science, 7, Article 594044. https://doi.org/10.3389/fvets.2020.594044

Extracellular vesicles are released by all cell types including stem cells. Stem cell-released extracellular vesicles have therapeutic effects similar to those of their parent cells and have regenerative effects in tissues. They also have an immunomo... Read More about Extracellular Vesicles: New Perspectives of Regenerative and Reproductive Veterinary Medicine.

Development of International Learning Outcomes for Shelter Medicine in Veterinary Education: A Delphi Approach (2020)
Journal Article
Stavisky, J., Watson, B., Dean, R., Merritt, B. L., Van Der Leij, R. W. J. R., & Serlin, R. (2021). Development of International Learning Outcomes for Shelter Medicine in Veterinary Education: A Delphi Approach. Journal of Veterinary Medical Education, 48(5), 610-619. https://doi.org/10.3138/jvme-2020-0027

Shelter medicine is a veterinary discipline of growing importance. Formally accepted as a clinical specialty in the US in 2014, the practice of shelter medicine worldwide is expanding. As a topic in veterinary pre-registration (undergraduate) educati... Read More about Development of International Learning Outcomes for Shelter Medicine in Veterinary Education: A Delphi Approach.

Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds (2020)
Journal Article
Morris, T. H., Paine, S. W., Zahra, P. W., Li, E. C., Colgan, S. .., & Karamatic, S. L. (2020). Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds. Australian Veterinary Journal, 98(12), 578-585. https://doi.org/10.1111/avj.13014

Animals used in sport should be treated as required to ensure animal welfare but any such use of medication should also be controlled to ensure integrity. Pharmacokinetic studies on groups of six greyhounds were performed to measure plasma and urine... Read More about Pharmacokinetics of carprofen and firocoxib for medication control in racing greyhounds.

Molecular characterisation of canine osteosarcoma in high risk breeds (2020)
Journal Article
Simpson, S., Dunning, M., de Brot, S., Alibhai, A., Bailey, C., Woodcock, C. L., …Rutland, C. S. (2020). Molecular characterisation of canine osteosarcoma in high risk breeds. Cancers, 12(9), Article 2405. https://doi.org/10.3390/cancers12092405

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dogs develop osteosarcoma (OSA) and the disease process closely resembles that of human OSA. OSA has a poor prognosis in both species and disease-free intervals and cure rates have not improve... Read More about Molecular characterisation of canine osteosarcoma in high risk breeds.

Evaluation of a pseudotyped virus neutralisation test for measurement of equine influenza A virus neutralizing antibody responses induced by vaccination and infection (2020)
Journal Article
Kinsley, R., Pronost, S., De Bock, M., Temperton, N., Daly, J. M., Paillot, R., & Scott, S. (2020). Evaluation of a pseudotyped virus neutralisation test for measurement of equine influenza A virus neutralizing antibody responses induced by vaccination and infection. Vaccines, 8(3), https://doi.org/10.3390/vaccines8030466

Equine influenza is a major respiratory disease of horses that is largely controlled by 24 vaccination in some equine populations. Virus-neutralizing antibodies, the mainstay of the protective 25 immune response, are problematic to assay for equine i... Read More about Evaluation of a pseudotyped virus neutralisation test for measurement of equine influenza A virus neutralizing antibody responses induced by vaccination and infection.

Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets (2020)
Journal Article
Kurozumi, S., Alsaleem, M., Monteiro, C. J., Bhardwaj, K., Joosten, S. E., Fujii, T., …Johnston, S. J. (2020). Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets. Breast Cancer Research, 22, Article 85. https://doi.org/10.1186/s13058-020-01324-4

© 2020 The Author(s). Background: Invasive lobular carcinoma (ILC) accounts for 10-15% of primary breast cancers and is typically estrogen receptor alpha positive (ER+) and ERBB2 non-amplified. Somatic mutations in ERBB2/3 are emerging as a tractable... Read More about Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets.

Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection (2020)
Journal Article
Sun, H., Xiao, Y., Liu, J., Wang, D., Li, F., Wang, C., …Liu, J. (2020). Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection. Proceedings of the National Academy of Sciences, 117(29), 17204-17210. https://doi.org/10.1073/pnas.1921186117

Pigs are intermediate hosts for the generation of pandemic influenza virus. Thus, systematic surveillance of influenza viruses in pigs is a key measure for prewarning the emergence of the next pandemic influenza. Here, we identified a reassortant EA... Read More about Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection.

Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes) (2020)
Journal Article
Moittié, S., Baiker, K., Strong, V., Cousins, E., White, K., Liptovszky, M., …Rutland, C. S. (2020). Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes). Scientific Reports, 10(1), https://doi.org/10.1038/s41598-020-66345-7

© 2020, The Author(s). Cardiovascular diseases, especially idiopathic myocardial fibrosis, is one of the most significant causes of morbidity and mortality in captive great apes. This study compared the structure and morphology of 16 hearts from chim... Read More about Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes).

First record of besnoitiosis caused by Besnoitia bennetti in donkeys from the UK (2020)
Journal Article
Elsheikha, H. M., Schares, G., Paraschou, G., Sullivan, R., & Fox, R. (2020). First record of besnoitiosis caused by Besnoitia bennetti in donkeys from the UK. Parasites and Vectors, 13, https://doi.org/10.1186/s13071-020-04145-8

Background: The involvement of Besnoitia bennetti in skin pathologies was investigated in a series of 20 donkeys from the Donkey Sanctuary in England, in the 2013-2019 period. Methods: The initial histopathological finding of Besnoitia cysts in skin... Read More about First record of besnoitiosis caused by Besnoitia bennetti in donkeys from the UK.

Metagenomics Reveals Impact of Geography and Acute Diarrhoeal Disease on the Central Indian Human Gut Microbiome (2020)
Journal Article
Monaghan, T. M., Sloan, T. J., Stockdale, S. R., Blanchard, A. M., Emes, R. D., Wilcox, M., …Singh Kashyap, R. (2020). Metagenomics Reveals Impact of Geography and Acute Diarrhoeal Disease on the Central Indian Human Gut Microbiome. Gut Microbes, 12(1), Article 1752605

Background: The Central Indian gut microbiome remains grossly understudied. Herein, we sought to investigate the burden of antimicrobial resistance and diarrhoeal diseases, particularly Clostridioides difficile, in rural-agricultural and urban popula... Read More about Metagenomics Reveals Impact of Geography and Acute Diarrhoeal Disease on the Central Indian Human Gut Microbiome.

Prediction of Pharmacokinetic Clearance and Potential Drug-Drug Interactions for Omeprazole in the Horse using in vitro Systems (2020)
Journal Article
Shibany, K. A., Pratt, S. L., Aldurdunji, M., Totemeyer, S., & Paine, S. W. (2020). Prediction of Pharmacokinetic Clearance and Potential Drug-Drug Interactions for Omeprazole in the Horse using in vitro Systems. Xenobiotica, 50(10), 1220-1227. https://doi.org/10.1080/00498254.2020.1764131

Horses are exposed to various kinds of medication, however, there are limited determinations of plasma clearance (CLp) for the drugs used due to the high cost of equine in vivo studies. Many of the CLp values generated come from the equine sports ind... Read More about Prediction of Pharmacokinetic Clearance and Potential Drug-Drug Interactions for Omeprazole in the Horse using in vitro Systems.

Canine collars: an investigation of collar type and the forces applied to a simulated neck model (2020)
Journal Article
Carter, A. J., Roshier, A. L., & McNally, D. S. (2020). Canine collars: an investigation of collar type and the forces applied to a simulated neck model. Veterinary Record, https://doi.org/10.1136/vr.105681

Background Dog collars have the potential to cause harm when the dog pulls on the lead. This study aimed to determine the effects of collar type and force applied using the lead, on the pressure on a simulated neck model. Methods Seven collars and a... Read More about Canine collars: an investigation of collar type and the forces applied to a simulated neck model.

Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species (2020)
Journal Article
Chappell, J. G., Tsoleridis, T., Onianwa, O., Drake, G., Ashpole, I., Dobbs, P., …McClure, C. P. (2020). Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species. Viruses, 12(4), Article 454. https://doi.org/10.3390/v12040454

©2020 by the authors. Licensee MDPI, Basel, Switzerland. Orthohantaviruses are globally distributed viruses, associated with rodents and other small mammals. However, data on the circulation of orthohantaviruses within the UK, particularly the UK-end... Read More about Retrieval of the Complete Coding Sequence of the UK-Endemic Tatenale Orthohantavirus Reveals Extensive Strain Variation and Supports Its Classification as a Novel Species.