All Outputs (30)

Long-term outcome following lateral foraminotomy as treatment for canine degenerative lumbosacral stenosis (2018)
Journal Article
Andrade Gomes, S., Lowrie, M., & Targett, M. (2018). Long-term outcome following lateral foraminotomy as treatment for canine degenerative lumbosacral stenosis. Veterinary Record, doi:10.1136/vr.104741. ISSN 0042-4900

Lateral foraminotomy has been described as an effective surgical treatment for foraminal stenosis in the treatment of degenerative lumbosacral stenosis (DLSS) in dogs. Clinical records were reviewed from 45 dogs which had undergone lateral foraminoto... Read More about Long-term outcome following lateral foraminotomy as treatment for canine degenerative lumbosacral stenosis.

Social interactions in two groups of zoo-housed adult female Asian elephants (Elephas maximus) that differ in relatedness (2018)
Journal Article
Harvey, N., Daly, C., Clark, N., Ransford, E., Wallace, S., & Yon, L. (2018). Social interactions in two groups of zoo-housed adult female Asian elephants (Elephas maximus) that differ in relatedness. Animals, 8(8), doi:10.3390/ani8080132. ISSN 2076-2615

Opportunities for positive social interaction are important in captive animals, and social interactions can be used as a welfare indicator. Wild elephants live in related multigenerational herds; however, in captivity they are often managed in less r... Read More about Social interactions in two groups of zoo-housed adult female Asian elephants (Elephas maximus) that differ in relatedness.

Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity (2018)
Journal Article
Schurink, A., da Silva, V. H., Velie, B. D., Dibbits, B. W., Crooijmans, R. P., Franҫois, L., …Ducro, B. J. (2018). Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity. BMC Genetics, 19, Article 49. https://doi.org/10.1186/s12863-018-0657-0

Background: Many common and relevant diseases affecting equine welfare have yet to be tested regarding structural variants such as copy number variations (CNVs). CNVs make up a substantial proportion of total genetic variability in populations of man... Read More about Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity.

Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice (2018)
Journal Article
Li, Z., Lu, J., Zhang, N., Elsheikha, H. M., Hou, J., Guo, H., & Zhu, X. (2018). Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice. Parasite, 25, Article 37. https://doi.org/10.1051/parasite/2018040

Toxoplasma gondii causes one of the most common protozoal diseases of humans and animals worldwide. With the aim of designing an effective vaccine against T. gondii infection, we examined the immunogenicity of a DNA vaccine expressing heat shock prot... Read More about Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice.

Comparative neuropathology of major Indian Bluetongue virus serotypes in a neonatal BALB/c mouse model (2018)
Journal Article
Anjaneya, A., Singh, K., Cherian, S., Saminathan, M., Singh, R., Ramakrishnan, M., …Mertens, P. (2018). Comparative neuropathology of major Indian Bluetongue virus serotypes in a neonatal BALB/c mouse model. Journal of Comparative Pathology, 162, 18-28. https://doi.org/10.1016/j.jcpa.2018.06.001

Bluetongue virus (BTV) is neurotropic in nature, especially in ruminant fetuses and in-utero infection results in abortion and congenital brain malformations. The aim of the present study was to compare the neuropathogenicity of major Indian BTV sero... Read More about Comparative neuropathology of major Indian Bluetongue virus serotypes in a neonatal BALB/c mouse model.

Adipogenic differentiation of muscle derived cells is repressed by inhibition of GSK-3 activity (2018)
Journal Article
Redshaw, Z., & Loughna, P. T. (2018). Adipogenic differentiation of muscle derived cells is repressed by inhibition of GSK-3 activity. Frontiers in Veterinary Science, 5, Article 110. https://doi.org/10.3389/fvets.2018.00110

Background: Intramuscular fat is important in large animal livestock species in regard to meat quality and in humans is of clinical significance in particular in relation to insulin resistance. The canonical Wnt signalling pathway has been implicated... Read More about Adipogenic differentiation of muscle derived cells is repressed by inhibition of GSK-3 activity.

Hepatic metabolomics investigation in acute and chronic murine toxoplasmosis (2018)
Journal Article
Chen, X., Elsheikha, H. M., Hu, R., Hu, G., Guo, S., Zhou, C., & Zhu, X. (2018). Hepatic metabolomics investigation in acute and chronic murine toxoplasmosis. Frontiers in Cellular and Infection Microbiology, 8, doi:10.3389/fcimb.2018.00189

Toxoplasma gondii poses a great threat to human health, with no approved vaccine available for the treatment of T. gondii infection. T. gondii infections are not limited to the brain, and may also affect other organs especially the liver. Identificat... Read More about Hepatic metabolomics investigation in acute and chronic murine toxoplasmosis.

Short- and long-term association between individual levels of milk antibody against Ostertagia ostertagi and first-lactation heifer’s production performances (2018)
Journal Article
Bellet, C., Green, M., Bradley, A., & Kaler, J. (2018). Short- and long-term association between individual levels of milk antibody against Ostertagia ostertagi and first-lactation heifer’s production performances. Veterinary Parasitology, 256, 1-8. https://doi.org/10.1016/j.vetpar.2018.04.008

It is agreed that exposure of adult dairy cattle to helminths on pasture can negatively affect production performances as milking herd. Young animals, especially replacement heifers, represent the future of a dairy farm and are among the most vulnera... Read More about Short- and long-term association between individual levels of milk antibody against Ostertagia ostertagi and first-lactation heifer’s production performances.

Joint genomic prediction of canine hip dysplasia in UK and US Labrador Retrievers (2018)
Journal Article
Edwards, S. M., Woolliams, J. A., Hickey, J. M., Blott, S. C., Clements, D. N., Sánchez-Molano, E., …Wiener, P. (2018). Joint genomic prediction of canine hip dysplasia in UK and US Labrador Retrievers. Frontiers in Genetics, 9, Article 101. https://doi.org/10.3389/fgene.2018.00101

Canine hip dysplasia, a debilitating orthopedic disorder that leads to osteoarthritis and cartilage degeneration, is common in several large-sized dog breeds and shows moderate heritability suggesting that selection can reduce prevalence. Estimating... Read More about Joint genomic prediction of canine hip dysplasia in UK and US Labrador Retrievers.

Inhibiting the ins and outs of HIV replication: cell-intrinsic antiretroviral restrictions at the plasma membrane (2018)
Journal Article
Foster, T. L., Pickering, S., & Neil, S. J. D. (2018). Inhibiting the ins and outs of HIV replication: cell-intrinsic antiretroviral restrictions at the plasma membrane. Frontiers in Immunology, 8, Article 1853. https://doi.org/10.3389/fimmu.2017.01853

© 2018 Foster, Pickering and Neil. Like all viruses, human immunodeficiency viruses (HIVs) and their primate lentivirus relatives must enter cells in order to replicate and, once produced, new virions need to exit to spread to new targets. These proc... Read More about Inhibiting the ins and outs of HIV replication: cell-intrinsic antiretroviral restrictions at the plasma membrane.