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Impaired forward model updating in young adults with Tourette syndrome (2018)
Journal Article
Kim, S., Jackson, G. M., Dyke, K., & Jackson, S. R. (2019). Impaired forward model updating in young adults with Tourette syndrome. Brain, 142(1), 209-219. doi:10.1093/brain/awy306

Current theories of motor control emphasise how the brain may use internal models of the body to ensure accurate planning and control of movements. One such internal model - a forward model - is thought to generate an estimate of the next motor state... Read More

The COMiT'ID study: developing core outcome domains sets for clinical trials of sound-, psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults (2018)
Journal Article
Hall, D. A., Smith, H., Hibbert, A., Colley, V., Haider, H. F., Horobin, A. J., …Core Outcome Measures in Tinnitus (COMiT), . (2018). The COMiT'ID study: developing core outcome domains sets for clinical trials of sound-, psychology-, and pharmacology-based interventions for chronic subjective tinnitus in adults. Trends in Hearing, doi:10.1177/2331216518814384

Subjective tinnitus is a chronic heterogeneous condition that is typically managed using intervention approaches based on sound devices, psychologically informed therapies, or pharmaceutical products. For clinical trials, there are currently no commo... Read More

Spatial attention affects the early processing of neutral versus fearful faces when they are task-irrelevant: a classifier study of the EEG C1 component (2018)
Journal Article
Acunzo, D., MacKenzie, G., & Van Rossum, M. (2019). Spatial attention affects the early processing of neutral versus fearful faces when they are task-irrelevant: a classifier study of the EEG C1 component. Cognitive, Affective, and Behavioral Neuroscience, 19(1), 123–137. doi:10.3758/s13415-018-00650-7

EEG studies suggest that the emotional content of visual stimuli is processed rapidly. In particular, the C1 component, which occurs up to 100 ms after stimulus onset and likely reflects activity in primary visual cortex V1, has been reported to be s... Read More

High variability phonetic training in adaptive adverse conditions is rapid, effective, and sustained (2018)
Journal Article
Leong, C. X. R., Price, J. M., Pitchford, N. J., & van Heuven, W. J. (2018). High variability phonetic training in adaptive adverse conditions is rapid, effective, and sustained. PLoS ONE, 13(10), (1-24). doi:10.1371/journal.pone.0204888. ISSN 1932-6203

This paper evaluates a novel high variability phonetic training paradigm that involves presenting spoken words in adverse conditions. The effectiveness, generalizability, and longevity of this high variability phonetic training in adverse conditions... Read More

Eating disorder symptomatology and body mass index are associated with readers’ expectations about character behavior: evidence from eye-tracking during reading (2018)
Journal Article
Ralph-Nearman, C., & Filik, R. (2018). Eating disorder symptomatology and body mass index are associated with readers’ expectations about character behavior: evidence from eye-tracking during reading. International Journal of Eating Disorders, 51(9), 1070-1079. doi:10.1002/eat.22961

Objective: Many theories have been put forward suggesting key factors underlying the development and maintenance of eating disorders, such as: unhealthy food-related cognitive biases, negative body attitude, and perfectionism; however, underlying cog... Read More

Understanding arithmetic concepts: the role of domain-specific and domain-general skills (2018)
Journal Article
Gilmore, C., Clayton, S., Cragg, L., McKeaveney, C., Simms, V., & Johnson, S. (2018). Understanding arithmetic concepts: the role of domain-specific and domain-general skills. PLoS ONE, doi:10.1371/journal.pone.0201724. ISSN 1932-6203

A large body of research has identified cognitive skills associated with overall mathematics achievement, focusing primarily on identifying associates of procedural skills. Conceptual understanding, however, has received less attention, despite its i... Read More

Cognitive predictors of parent-rated inattention in very preterm children: the role of working memory and processing speed (2018)
Journal Article
Retzler, J., Johnson, S., Groom, M., Hollis, C., Budge, H., & Cragg, L. (2018). Cognitive predictors of parent-rated inattention in very preterm children: the role of working memory and processing speed. Child Neuropsychology, doi:10.1080/09297049.2018.1510908

Background: Inattention is one of the most common neurobehavioural problems following very preterm birth. Attention problems can persist into adulthood and are associated with negative socio-emotional and educational outcomes. This study aimed to det... Read More

Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment (2018)
Journal Article
Meng, D., Li, X., Bauer, M., Taylor, J., Auer, D. P., & Alzheimer's Disease Neuroimaging Initiative, . (2018). Altered nucleus basalis connectivity predicts treatment response in mild cognitive impairment. Radiology, 2018, doi:10.1148/radiol.2018180092

Purpose: To determine whether functional connectivity (FC) mapping of nucleus basalis of Meynert (NBM) cholinergic network (hereafter, NBM FC) could provide a biomarker of central cholinergic deficits with predictive potential for response to choline... Read More

Visuomotor learning and unlearning in children and adolescents with Tourette syndrome (2018)
Journal Article
Kim, S., Jackson, S. R., Groom, M., & Jackson, G. M. (2018). Visuomotor learning and unlearning in children and adolescents with Tourette syndrome. Cortex, 109, 50-59. doi:10.1016/j.cortex.2018.08.007

Tourette syndrome (TS) is a childhood-onset neurological condition characterised by an evolving repertoire of chronic motor tics and one or more phonic tics. Tics, like habits, are inflexible and repetitive behaviours that are acquired over a period... Read More

Mathematics students demonstrate superior visuo-spatial working memory to humanities students under conditions of low central executive processing load (2018)
Journal Article
Hubber, P. J., Gilmore, C., & Cragg, L. (in press). Mathematics students demonstrate superior visuo-spatial working memory to humanities students under conditions of low central executive processing load. Journal of Numerical Cognition,

Previous research has demonstrated that working memory performance is linked to mathematics achievement. Most previous studies have involved children and arithmetic rather than more advanced forms of mathematics. This study compared the performance o... Read More

The threshold for the McGurk effect in audio-visual noise decreases with development (2018)
Journal Article
Hirst, R. J., Stacey, J. E., Cragg, L., Stacey, P. C., & Allen, H. A. (2018). The threshold for the McGurk effect in audio-visual noise decreases with development. Scientific Reports, 8, doi:10.1038/s41598-018-30798-8

Across development, vision increasingly influences audio-visual perception. This is evidenced in illusions such as the McGurk effect, in which a seen mouth movement changes the perceived sound. The current paper assessed the effects of manipulating t... Read More

Differentiating ‘the user’ in DSR: developing demand side response in advanced economies (2018)
Journal Article
Goulden, M., Spence, A., Wardman, J., & Leygue, C. (2018). Differentiating ‘the user’ in DSR: developing demand side response in advanced economies. Energy Policy, 122, (176-185). doi:10.1016/j.enpol.2018.07.013. ISSN 0301-4215

This paper reports on the current state of Demand Side Response (DSR) in the UK – an early adoptor amongst advanced economies – and the role of the end user in determining its future. Through 21 expert interviews we establish the current state of DSR... Read More

A spiral attractor network drives rhythmic locomotion (2017)
Journal Article
Bruno, A. M., Frost, W. N., & Humphries, M. D. (2017). A spiral attractor network drives rhythmic locomotion. eLife, 6, doi:10.7554/elife.27342. ISSN 2050-084X

The joint activity of neural populations is high dimensional and complex. One strategy for reaching a tractable understanding of circuit function is to seek the simplest dynamical system that can account for the population activity. By imaging Aplysi... Read More

Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations (2017)
Journal Article
Fulton, J., Mazumder, B., Whitchurch, J., Monteiro, C. J., Collins, H. M., Chan, C. M., …Heery, D. M. (2017). Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations. Cell Death and Disease, 8, doi:10.1038/cddis.2017.98

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the Nuclear Receptor (NR) superfamily of transcription factors. We assessed... Read More

Modular deconstruction reveals the dynamical and physical building blocks of a locomotion motor program (2015)
Journal Article
Bruno, A., Frost, W., & Humphries, M. (2015). Modular deconstruction reveals the dynamical and physical building blocks of a locomotion motor program. Neuron, 86(1), (304-318). doi:10.1016/j.neuron.2015.03.005. ISSN 0896-6273

The neural substrates of motor programs are only well understood for small, dedicated circuits. Here we investigate how a motor program is constructed within a large network. We imaged populations of neurons in the Aplysia pedal ganglion during execu... Read More

A new framework for cortico-striatal plasticity: behavioural theory meets In vitro data at the reinforcement-action interface (2015)
Journal Article
Gurney, K. N., Humphries, M. D., & Redgrave, P. (2015). A new framework for cortico-striatal plasticity: behavioural theory meets In vitro data at the reinforcement-action interface. PLoS Biology, 13(1), doi:10.1371/journal.pbio.1002034. ISSN 1544-9173

Operant learning requires that reinforcement signals interact with action representations at a suitable neural interface. Much evidence suggests that this occurs when phasic dopamine, acting as a reinforcement prediction error, gates plasticity at co... Read More