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3D printed scaffolds with controlled micro-/nano- porous surface topography direct chondrogenic and osteogenic differentiation of mesenchymal stem cells (2019)
Journal Article
Prasopthum, A., Cooper, M., Shakesheff, K. M., & Yang, J. (in press). 3D printed scaffolds with controlled micro-/nano- porous surface topography direct chondrogenic and osteogenic differentiation of mesenchymal stem cells. ACS Applied Materials and Interfaces,

The effect of topography in 3D printed polymer scaffolds on stem cell differentiation is a significantly under-explored area. Compared to 2D biomaterials on which various well-defined topographies have been incorporated and been shown to direct an ar... Read More

Probing elusive cations: infrared spectroscopy of protonated acetic acid (2019)
Journal Article
Davies, J. A., Besley, N. A., Yang, S., & Ellis, A. M. (2019). Probing elusive cations: infrared spectroscopy of protonated acetic acid. Journal of Physical Chemistry Letters, 10, 2108-2112. doi:10.1021/acs.jpclett.9b00767

Protonated carboxylic acids, (RCOOH)H+, are the initial intermediates in acid-catalyzed (Fischer) esterification reactions. However the identity of the isomeric form is under debate. Surprisingly, no optical spectra have been reported for any isomer... Read More

Turning the periodic table upside down (2019)
Journal Article
Poliakoff, M., Makin, A. D. J., Tang, S. L. Y., & Poliakoff, E. (2019). Turning the periodic table upside down. Nature Chemistry, doi:10.1038/s41557-019-0253-6

The periodic table is immensely powerful for rationalizing many different properties of the chemical elements, but would turning it on its head make some important aspects easier to understand and give everyone a new perspective on chemistry?

Combining continuous flow oscillatory baffled reactors and microwave heating: process intensification and accelerated synthesis of metal-organic frameworks (2018)
Journal Article
Laybourn, A., López-Fernández, A. M., Thomas-Hillman, I., Katrib, J., Lewis, W., Dodds, C., …Kingman, S. W. (2018). Combining continuous flow oscillatory baffled reactors and microwave heating: process intensification and accelerated synthesis of metal-organic frameworks. Chemical Engineering Journal, doi:10.1016/j.cej.2018.09.011. ISSN 1385-8947

We have constructed a continuous flow oscillatory baffled reactor (CF-OBR) equipped with a homogeneous and controllable microwave applicator in an entirely novel design. This affords a new route to chemical production incorporating many of the princi... Read More

Formation of hollow carbon nanoshells from thiol stabilised silver nanoparticles via heat treatment (2018)
Journal Article
Watts, J. A., Fay, M. W., Rance, G. A., Brown, P. D., & Khlobystov, A. N. (2018). Formation of hollow carbon nanoshells from thiol stabilised silver nanoparticles via heat treatment. Carbon, 139, (538-544). doi:10.1016/j.carbon.2018.06.074. ISSN 0008-6223

Uniform, less 10 nm sized, hollow carbon nano-shells (HCNS) have been prepared via a single-step, thermal treatment of alkanethiol stabilised Ag nanoparticles (TS-AgNP). Direct evidence for the formation of spherical HCNS from TS-AgNP is provided by... Read More

Carbene in cupredoxin protein scaffolds: replacement of a histidine ligand in the active site substantially alters copper redox properties (2018)
Journal Article
Planchestainer, M., Segaud, N., Shanmugam, M., McMaster, J., Paradisi, F., & Albrecht, M. (2018). Carbene in cupredoxin protein scaffolds: replacement of a histidine ligand in the active site substantially alters copper redox properties. Angewandte Chemie International Edition, 57(33), (10677-10682). doi:10.1002/anie.201807168. ISSN 1433-7851

N-heterocyclic carbene (NHC) ligands have had a major impact in homogeneous catalysis, however, their potential role in biological systems is essentially unexplored. Here we replaced a copper-coordinating histidine (His) in the active site of azurin... Read More

Tuning the electronic structure of organic–inorganic hybrid polyoxometalates: The crucial role of the covalent linkage (2018)
Journal Article
Kibler, A. J., & Newton, G. N. (2018). Tuning the electronic structure of organic–inorganic hybrid polyoxometalates: The crucial role of the covalent linkage. Polyhedron, 154, 1-20. doi:10.1016/j.poly.2018.06.027

The covalent organofunctionalization of polyoxometalates (POMs) has been widely used to both control and enhance their redox properties, particularly for applications in catalysis, energy storage, optics and molecular magnetism. The design of such sy... Read More

Enantioselective synthesis of chiral cyclopent-2-enones by nickel-catalyzed desymmetrization of malonate esters (2018)
Journal Article
Karad, S. N., Panchal, H., Clarke, C., Lewis, W., & Lam, H. W. (2018). Enantioselective synthesis of chiral cyclopent-2-enones by nickel-catalyzed desymmetrization of malonate esters. Angewandte Chemie International Edition, 57(29), (9122-9125). doi:10.1002/anie.201805578. ISSN 1433-7851

The enantioselective synthesis of highly functionalized chiral cyclopent‐2‐enones by the reaction of alkynyl malonate esters with arylboronic acids is described. These desymmetrizing arylative cyclizations are catalyzed by a chiral phosphinooxazoline... Read More

The role of adsorbed ions during electrocatalysis in ionic liquids (2014)
Journal Article
Ejigu, A., & Walsh, D. A. (2014). The role of adsorbed ions during electrocatalysis in ionic liquids. Journal of Physical Chemistry C, 118(14), (7414-7422). doi:10.1021/jp411730z. ISSN 1932-7447

The effects of electrode–adsorbate interactions on electrocatalysis at Pt in ionic liquids are described. The ionic liquids are diethylmethylammonium trifluoromethanesulfonate, [dema][TfO], dimethylethylammonium trifluoromethanesulfonate, [dmea][TfO]... Read More