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All Outputs (39)

Use of mirtazapine in patients with chronic breathlessness: a case series (2018)
Journal Article
Lovell, N., Bajwah, S., Maddocks, M., Wilcock, A., & Higginson, I. J. (2018). Use of mirtazapine in patients with chronic breathlessness: a case series. Palliative Medicine, doi:10.1177/0269216318787450. ISSN 1477-030X

Background: Breathlessness remains a common and distressing symptom in people with advanced disease with few effective treatment options. Repurposing of existing medicines has been effective in other areas of palliative care, for example, antidepres... Read More about Use of mirtazapine in patients with chronic breathlessness: a case series.

Identifying key components for a psychological intervention for people with vitiligo: a quantitative and qualitative study in the United Kingdom using web-based questionnaires of people with vitiligo and healthcare professionals (2018)
Journal Article
Ahmed, A., Steed, L., Burden-Teh, E., Shah, R., Sanyal, S., Tour, S., …Bewley, A. (2018). Identifying key components for a psychological intervention for people with vitiligo: a quantitative and qualitative study in the United Kingdom using web-based questionnaires of people with vitiligo and healthcare professionals. Journal of the European Academy of Dermatology and Venereology, 32(12), 2275-2283. https://doi.org/10.1111/jdv.15168

Background: Psychological interventions are recommended as part of routine management of vitiligo. However, the development and effectiveness of such interventions have been rarely addressed. This study aimed to identify key components for a psycholo... Read More about Identifying key components for a psychological intervention for people with vitiligo: a quantitative and qualitative study in the United Kingdom using web-based questionnaires of people with vitiligo and healthcare professionals.

Risk of bleeding with direct oral anticoagulants versus warfarin: cohort studies using primary care datasets (2018)
Journal Article
Vinogradova, Y., Coupland, C., Hill, T., & Hippisley-Cox, J. (2018). Risk of bleeding with direct oral anticoagulants versus warfarin: cohort studies using primary care datasets. British Journal of General Practice, 68(suppl 1), doi:10.3399/bjgp18X696629

Background: There is limited evidence on the safety of direct oral anticoagulants (DOACs) in real world settings. Aim: To investigate risks of bleeding and all-cause mortality in DOACs compared to warfarin. Method: Prospective cohorts of incide... Read More about Risk of bleeding with direct oral anticoagulants versus warfarin: cohort studies using primary care datasets.

Panoptic overview of triple-negative breast cancer in Nigeria: current challenges and promising global initiatives (2018)
Journal Article
Wright, N., Rida, P., Rakha, E., Agboola, A., & Aneja, R. (2018). Panoptic overview of triple-negative breast cancer in Nigeria: current challenges and promising global initiatives. Journal of Global Oncology, 1-20. https://doi.org/10.1200/jgo.17.00116

Purpose Triple-negative breast cancer (TNBC) is the most deadly form of breast cancer (BC) today. TNBC treatment is fraught with challenges because of the extensive interpatient heterogeneity in clinical behavior and scarcity of stratifying biomar... Read More about Panoptic overview of triple-negative breast cancer in Nigeria: current challenges and promising global initiatives.

Managing health, safety and well-being: ethics, responsibility and sustainability (2018)
Book
Jain, A., Leka, S., & Zwetsloot, G. I. (2018). Managing health, safety and well-being: ethics, responsibility and sustainability. Springer Nature. doi:10.1007/978-94-024-1261-1

To achieve sustainable progress in workplace and societal functioning and development, it is essential to align perspectives for the management of health, safety and well-being. Employers are responsible for providing every individual with a working... Read More about Managing health, safety and well-being: ethics, responsibility and sustainability.

Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7?T and 3?T: The Impact of the Experimental Design (2018)
Journal Article
De Santis, S., Bastiani, M., Droby, A., Kolber, P., Zipp, F., Pracht, E., …Roebroeck, A. (2019). Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7 T and 3 T: The Impact of the Experimental Design. Neuroscience, 403, 17-26. https://doi.org/10.1016/j.neuroscience.2018.03.048

© 2018 The Author(s) The recent introduction of advanced magnetic resonance (MR) imaging techniques to characterize focal and global degeneration in multiple sclerosis (MS), like the Composite Hindered and Restricted Model of Diffusion, or CHARMED, d... Read More about Characterizing Microstructural Tissue Properties in Multiple Sclerosis with Diffusion MRI at 7?T and 3?T: The Impact of the Experimental Design.

Responding to domestic violence and abuse: considerations for health visitors (2018)
Journal Article
McGarry, J., & Ali, P. (2018). Responding to domestic violence and abuse: considerations for health visitors. Journal of Health Visiting, 6(2), 95-98. doi:10.12968/johv.2018.6.2.95

Domestic violence and abuse (DVA) exerts a significant impact on the lives, health and wellbeing of all of those who experience it and this includes children. Health professionals in a variety of settings are well placed to identify potential DVA cas... Read More about Responding to domestic violence and abuse: considerations for health visitors.

The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction (2018)
Journal Article
Makropoulos, A., Robinson, E. C., Schuh, A., Wright, R., Fitzgibbon, S., Bozek, J., …Rueckert, D. (2018). The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction. NeuroImage, 173, 88-112. https://doi.org/10.1101/125526

The Developing Human Connectome Project (dHCP) seeks to create the first 4-dimensional connectome of early life. Understanding this connectome in detail may provide insights into normal as well as abnormal patterns of brain development. Following est... Read More about The Developing Human Connectome Project: a minimal processing pipeline for neonatal cortical surface reconstruction.

The challenges of training, support and assessment of healthcare support workers: a qualitative study of experiences in three English acute hospitals (2017)
Journal Article
Sarre, S., Maben, J., Aldus, C., Schneider, J., Wharrad, H., Nicholson, C., & Arthur, A. (2018). The challenges of training, support and assessment of healthcare support workers: a qualitative study of experiences in three English acute hospitals. International Journal of Nursing Studies, 79, 145-153. https://doi.org/10.1016/j.ijnurstu.2017.11.010

Background Ever-growing demands on care systems have increased reliance on healthcare support workers. In the UK, their training has been variable, but organisation-wide failures in care have prompted questions about how this crucial section of the... Read More about The challenges of training, support and assessment of healthcare support workers: a qualitative study of experiences in three English acute hospitals.

Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data (2017)
Journal Article
Achana, F., Fleming, K., Tata, L., Sultan, A. A., & Petrou, S. (2018). Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data. BJOG: An International Journal of Obstetrics and Gynaecology, 125(7), 874-883. https://doi.org/10.1111/1471-0528.14950

Objective To estimate resource use and costs associated with peripartum hysterectomy for the English National Health Service. Design/Setting Analysis of linked Clinical Practice Research Datalink and Hospital Episodes Statistics (CPRD‐HES) data.... Read More about Peripartum hysterectomy: an economic analysis of direct healthcare costs using routinely collected data.

Towards a comprehensive framework for movement and distortion correction of diffusion MR images: within volume movement (2017)
Journal Article
Andersson, J. L., Graham, M. S., Drobnjak, I., Zhang, H., Filippini, N., & Bastiani, M. (2017). Towards a comprehensive framework for movement and distortion correction of diffusion MR images: within volume movement. NeuroImage, 152, 450-466. https://doi.org/10.1016/j.neuroimage.2017.02.085

Most motion correction methods work by aligning a set of volumes together, or to a volume that represents a reference location. These are based on an implicit assumption that the subject remains motionless during the several seconds it takes to acqui... Read More about Towards a comprehensive framework for movement and distortion correction of diffusion MR images: within volume movement.

CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation (2017)
Journal Article
Siddiqui, Y. H., Kershaw, R. M., Humphreys, E. H., Marcolino de Assis Junior, E., Chaudhri, S., Jayaraman, P., & Gaston, K. (2017). CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation. Oncogenesis, 6, https://doi.org/10.1038/oncsis.2016.82

PRH/HHEX (Proline Rich Homeodomain protein/Haematopoietically-Expressed Homeobox protein) is a transcription factor that controls cell proliferation, cell differentiation and cell migration. Our previous work has shown that in haematopoietic cells Pr... Read More about CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation.

Automatic segmentation of human cortical layer-complexes and architectural areas using ex vivo diffusion MRI and its validation (2016)
Journal Article
Bastiani, M., Oros-Peusquens, A., Seehaus, A., Brenner, D., Möllenhoff, K., Celik, A., …Roebroeck, A. (2016). Automatic segmentation of human cortical layer-complexes and architectural areas using ex vivo diffusion MRI and its validation. Frontiers in Neuroscience, 10, Article 487. https://doi.org/10.3389/fnins.2016.00487

Recently, several magnetic resonance imaging contrast mechanisms have been shown to distinguish cortical substructure corresponding to selected cortical layers. Here, we investigate cortical layer and area differentiation by automatized unsupervised... Read More about Automatic segmentation of human cortical layer-complexes and architectural areas using ex vivo diffusion MRI and its validation.

Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial) (2016)
Journal Article
Knapp, M., King, D., Romeo, R., Adams, J., Baldwin, A., Ballard, C., …Howard, R. (2016). Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial). International Journal of Geriatric Psychiatry, 32(12), 1205-1216. https://doi.org/10.1002/gps.4583

© 2016 The Authors. International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd. Objective: Most investigations of pharmacotherapy for treating Alzheimer's disease focus on patients with mild-to-moderate symptoms, with little e... Read More about Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial).

The consequences of tinnitus and tinnitus severity on cognition: A review of the behavioural evidence (2015)
Journal Article
Mohamad, N., Hoare, D. J., & Hall, D. A. (2016). The consequences of tinnitus and tinnitus severity on cognition: A review of the behavioural evidence. Hearing Research, 332, 199-209. https://doi.org/10.1016/j.heares.2015.10.001

People with tinnitus report anecdotal difficulties in mental concentration and psychological treatments for tinnitus advise on concentration difficulties and how to manage them. Yet the literature lacks any coherent discussion about what precise theo... Read More about The consequences of tinnitus and tinnitus severity on cognition: A review of the behavioural evidence.

Biomimetic direction of arrival estimation for resolving front-back confusions in hearing aids (2015)
Journal Article
Archer-Boyd, A. W., Whitmer, W. M., Brimijoin, W. O., & Soraghan, J. J. (2015). Biomimetic direction of arrival estimation for resolving front-back confusions in hearing aids. Journal of the Acoustical Society of America, 137(5), doi:10.1121/1.4918297

Sound sources at the same angle in front or behind a two-microphone array (e.g., bilateral hearing aids) produce the same time delay and two estimates for the direction of arrival: A front-back confusion. The auditory system can resolve this issue us... Read More about Biomimetic direction of arrival estimation for resolving front-back confusions in hearing aids.