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Formulation of Bioerodible Ketamine Microparticles as an Analgesic Adjuvant Treatment Produced by Supercritical Fluid Polymer Encapsulation (2018)
Journal Article
Han, F., Whittaker, A., Howdle, S., Naylor, A., Shabir-Ahmed, A., Zhang, C., & Smith, M. (2018). Formulation of Bioerodible Ketamine Microparticles as an Analgesic Adjuvant Treatment Produced by Supercritical Fluid Polymer Encapsulation. Pharmaceutics, 10(4), doi:10.3390/pharmaceutics10040264

Pain is inadequately relieved by escalating doses of a strong opioid analgesic such as morphine in up to 25% of patients with cancer-related severe pain complicated by a neuropathic (nerve damage) component. Hence, there is an unmet medical need for... Read More